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Embryo's heartbeat drives blood stem cell formation

Biologists have long wondered why the embryonic heart begins beating so early, before the tissues actually need to be infused with blood.

Bone marrow stem cell co-transplantation prevents embryonic stem cell transplant-associated tumors

Tampa, Fla. (May. 11, 2009) - Transplanted embryonic stem cells are recognized as a potential treatment for patients suffering from the effects of spinal cord injury (SCI). However, in studies using embryonic stem cells transplanted into SCI laboratory animals, a serious drawback has been the development of tumors following transplantation.

Study finds novel genetic risk factors for kidney disease

A team of researchers from the United States, the Netherlands and Iceland has identified three genes containing common mutations that are associated with altered kidney disease risk. One of the discovered genes, the UMOD gene, produces Tamm-Horsfall protein, the most common protein in the urine of healthy individuals.

Autologous muscle-derived cells may treat stress urinary incontinence

LINTHICUM, MD, April 26, 2009-Researchers have confirmed that transplanting autologous muscle-derived cells (AMDC) into the bladder is safe at a wide range of doses and significantly improves symptoms and quality of life in patients with stress urinary incontinence.

HIV positive and HIV negative patients have similar survival rates following liver transplant

Copenhagen, Denmark, Friday 24 April: HIV positive and HIV negative patients have comparable survival rates following liver transplant, according to new research presented today at EASL 2009, the Annual Meeting of the European Association for the Study of Liver in Copenhagen, Denmark.

Majority of doctors skeptical of organ transplantation practices in China

The globalization of health care and the growth of "transplant tourism" (traveling abroad to purchase donor organs and undergo organ transplantation) have outpaced the implementation of internationally accepted ethical standards for procurement of organs for transplantation. A new article appearing in Clinical Transplantation finds that both U.S.

'Nature vs. nurture' study of deceased donor pairs in kidney transplantation

Minneapolis/St. Paul, MN - The implications of a new study could improve the outcomes, and potentially survival rates, for some of the thousands of individuals who undergo kidney transplants each year. The study concluded that donor-related risk factors, yet to be identified, make a measurable contribution to the ultimate success or failure of a kidney transplant.

Indigenous peoples at world summit to share climate change observations, coping techniques

With the first climate change-related relocation of an Inuit village already underway, some 400 Indigenous People and observers from 80 nations are convening in Alaska for a UN-affiliated conference April 20-24 to discuss ways in which traditional knowledge can be used to both mitigate and adapt to climate change.

Transplanted liver cells function in older animals but do not proliferate as much as in younger ones

When things go right, transplanted healthy liver cells transplanted by infusion or injection will find their way to the liver, integrate into the damaged tissue, start proliferating, and take over the liver's work of helping with digestion and removing waste products and worn-out cells from the blood.

Use of pancreatic islets show promise in diabetes research, treatments

The use of pancreatic islets (hormone-producing cells) is increasing in diabetes research and may play an important role in future treatments, according to an article in the April 15 issue of JAMA, a theme issue on diabetes.

Creating ideal neural cells for clinical use

LA JOLLA, Calif., April 13, 2009 -- Investigators at the Burnham Institute for Medical Research (Burnham) have developed a protocol to rapidly differentiate human embryonic stem cells (hESCs) into neural progenitor cells that may be ideal for transplantation.

Device protects transplanted pancreatic cells from the immune system

LA JOLLA, Calif., April 9, 2009--Scientists at Burnham Institute for Medical Research (Burnham) and the University of California San Diego (UC San Diego) School of Medicine have demonstrated in mice that transplanted pancreatic precursor cells are protected from the immune system when encapsulated in polytetrafluorethylene (PTFE).

Major breakthrough in transplantation immunity

Australian scientists have made a discovery that may one day remove the need for a lifetime of toxic immunosuppressive drugs after organ transplants.

Ambati study published in PNAS

LEXINGTON, Ky. (April 6, 2009) - The side effects of an experimental "gene-silencing" treatment that is currently being investigated for a variety of diseases are even more wide-ranging than previously discovered, according to a study by a University of Kentucky researcher.

Artificial pump effectively backs up failing hearts

Patients with severe heart failure can be bridged to eventual transplant by a new, smaller and lighter implantable heart pump, according to a just-completed study of the device. Results of this third-generation heart assist device were reported at the 58th annual meeting of the American College of Cardiology on March 30.



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