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Induced pluripotent stem cells repair heart, Mayo Clinic study shows

ROCHESTER, Minn. -- In a proof-of-concept study, Mayo Clinic investigators have demonstrated that induced pluripotent stem (iPS) cells can be used to treat heart disease. iPS cells are stem cells converted from adult cells.

New role discovered for molecule important in development of the pancreas

PHILADELPHIA -- For years researchers have been searching for a way to treat diabetics by reactivating their insulin-producing beta cells, to no avail. Now, they may be one step closer.

Trio of signals converge to induce liver and pancreas cell development in the embryo

PHILADELPHIA - Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used for new therapies.

Human term placenta a new abundant source of hematopoietic cells

Investigators at Children's Hospital Oakland Research Institute, Oakland, California found a way to obtain large numbers of hematopoietic stem cell from human term placenta.

Children's Hospital Oakland scientists first to discover new source for harvesting stem cells

A study conducted by Children's Hospital & Research Center Oakland is the first to reveal a new avenue for harvesting stem cells from a woman's placenta, or more specifically the discarded placentas of healthy newborns. The study also finds there are far more stem cells in placentas than in umbilical cord blood, and they can be safely extracted for transplantation.

Physicians frequently fail to inform patients about abnormal test results

NEW YORK (June 22, 2009) -- New research shows that physicians failed to report clinically significant abnormal test results to patients -- or to document that they had informed them -- in one out of every 14 cases of abnormal results. In some medical groups, the failure rate is close to zero; in others it is as high as one in four abnormal results.

Medical insurance documents shed light on kidney transplant patients' health

Billing claims from health insurance companies can provide insights on the long-term health of kidney transplant patients, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).

Nearly half of older patients projected to die while waiting for kidney transplant

Forty-six percent of patients over age 60 currently on the waiting list for a kidney transplant will die before they receive an organ from a deceased donor, reports an upcoming study in the Clinical Journal of the American Society of Nephrology (CJASN).

Test detects molecular marker of aging in humans

CHAPEL HILL, N.C. -- In 2004, researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center announced a crucial discovery in the understanding of cellular aging. They found that as cells and tissues age, the expression of a key protein, called p16INK4a, dramatically increases in most mammalian organs.

Predicting fatal fungal infections

June 15, 2009 -- (BRONX, NY) -- In a study published in The Journal of Infectious Diseases, researchers from Albert Einstein College of Medicine of Yeshiva University have identified cells in blood that predict which HIV-positive individuals are most likely to develop deadly fungal meningitis, a major cause of HIV-related death.

Study finds segregation decreases access to surgical care for minorities

CHICAGO (June 11, 2009) -- New research published in the June issue of the Journal of the American College of Surgeons reveals that in counties with the highest levels of segregation, an increase in the African-American or Hispanic population was associated with a decrease in the availability and use of surgical services and an increase in the number of emergency room visits.

Trimming the fat boosts blood recovery after marrow transplant

Seeking ways to improve blood recovery after chemotherapy or bone marrow transplant, researchers at Children's Hospital Boston have discovered that fat cells, which accumulate in bone marrow as people age, inhibit the marrow's ability to produce new blood cells.

Sight for sore eyes

In a world-first breakthrough, University of New South Wales (UNSW) medical researchers have used stem cells cultured on a simple contact lens to restore sight to sufferers of blinding corneal disease.

Sight was significantly improved within weeks of the procedure, which is simple, inexpensive and requires a minimal hospital stay.

Study IDs benefit of donor SCT for adults with acute myeloid leukemia

BOSTON--A stem cell transplant (SCT) from a compatible donor early in the course of disease is the best approach for the majority of young and middle-aged adult patients with acute myeloid leukemia (AML), according to a new analysis of two dozen clinical studies.

Recruitment of reproductive features into other cell types may underlie extended lifespan in animals

In the sense that organisms existing today are connected through a chain of life -- through their parents, grandparents and other ancestors -- almost a billion years back to the first animals of the pre-Cambrian era, an animal's reproductive cells can be considered to be immortal.



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