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Telltale moss

Hikers know that moss on a tree trunk always points north. According to new research by Israeli and German scientists, this ancient plant may also provide a new "compass" for stem cell research, telling scientists how better to program stem cells for medical purposes.

New study resolves the mysterious origin of Merkel cells

A new study resolves a 130-year-old mystery over the developmental origin of specialized skin cells involved in touch sensation. The findings will appear in the October 5, 2009 issue of the Journal of Cell Biology (online September 28).

Pitt researchers net $5 million from NIH to explore better ways to grow cells

PITTSBURGH -- Regenerative medicine researchers at the University of Pittsburgh received two grants totaling more than $5 million from the National Institutes of Health (NIH) to explore new methods for cultivating replacement cells from existing tissues and organs.

Reactive oxygen in fruit flies acts as a cell signalling mechanism for immune response

For years, health conscious people have been taking antioxidants to reduce the levels of reactive oxygen in their blood and prevent the DNA damage done by free radicals, which are the result of oxidative stress. But could excessive use of antioxidants deplete our immune systems?

Research at UCLA's Jonsson Comprehensive Cancer Center has raised that question.

Novel 'on-off switch' mechanism stops cancer in its tracks

A tiny bit of genetic material with no previously known function may hold the key to stopping the spread of cancer, researchers at Yale School of Medicine and Sichuan University in Chengdu, China report in two papers in the September 7-11 issue of Proceedings of the National Academy of Sciences.

New study finds way to stop excessive bone growth following trauma or surgery

(PHILADELPHIA) -- A recent United States Army study found that excessive bone growth, also known as heterotopic ossificiation (HO), affects up to 70 percent of soldiers who are severely wounded during combat. A much smaller percentage of the civilian population also suffers from HO following trauma or invasive surgery.

Role of Cancer Stem Cells in the Development of the Tumor Vasculature

September 21, 2009 by jenwjw

A common strategy to stop tumor growth is to cut the tumor's blood supply, usually by inhibiting angiogenic factors such as the vascular endothelial growth factor (VEGF). However, recent evidence suggests that anti-angiogenic therapy could also enhance tumor growth and invasiveness in the long-term [1].

Echoes of phlogiston in stem cell biology

Before it was learned that matter burns by taking up oxygen, most chemists sought to explain combustion as the release of a mysterious substance, which they named "phlogiston". Phlogiston theory was a conceptual breakthrough that helped chemists conduct experiments and share ideas.

Memories of the way they used to be

A team of researchers from the University of California, San Diego School of Medicine and the Salk Institute for Biological Studies in La Jolla have developed a safe strategy for reprogramming cells to a pluripotent state without use of viral vectors or genomic insertions.

Penn State College of Medicine research isolates liver cancer stem cells prior to tumor formation

HERSHEY, PA -- Penn State College of Medicine researchers, in collaboration with colleagues at the University of Southern California, have taken an important step in understanding the role of stem cells in development of liver cancer. Using a unique approach that involves study of individual cells, the team, led by C.

Blood vessels contribute to their own growth and oxygen delivery to tissues and tumors

CHAPEL HILL -- Researchers at the University of North Carolina at Chapel Hill School of Medicine and the College of Arts & Sciences have identified a new biological process that spurs the growth of new blood vessels.

Diabetes drug kills cancer stem cells in combination treatment in mice

PHILADELPHIA -- In a one-two punch, a familiar diabetes drug reduced tumors faster and prolonged remission in mice longer than chemotherapy alone by targeting cancer stem cells, Harvard Medical School researchers reported in the September 14 online first edition of Cancer Research, a journal of the American Association for Cancer Research.

Diabetes drug kills cancer stem cells in combination treatment in mice

BOSTON, Mass. (September 14, 2009) -- In a one-two punch, a familiar diabetes drug reduced tumors faster and prolonged remission in mice longer than chemotherapy alone, apparently by targeting cancer stem cells, report Harvard Medical School researchers in the Sept. 14 advance online Cancer Research.

How stem cells make skin

Stem cells have a unique ability: when they divide, they can either give rise to more stem cells, or to a variety of specialised cell types. In both mice and humans, a layer of cells at the base of the skin contains stem cells that can develop into the specialised cells in the layers above.

Master gene that switches on disease-fighting cells identified by scientists

The master gene that causes blood stem cells to turn into disease-fighting 'Natural Killer' (NK) immune cells has been identified by scientists, in a study published in Nature Immunology today. The discovery could one day help scientists boost the body's production of these frontline tumour-killing cells, creating new ways to treat cancer.



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