regenerative medicine
CHICAGO --- The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in less pain and an improved ability to walk. The transplant subjects also experienced fewer deaths than those who didn't receive stem cells.
The recent creation of live mice from induced pluripotent stem cells
(iPSCs) not only represents a remarkable scientific achievement, but also raises important issues, according to bioethicists at
Scientists have for the first time produced liver cells from adult skin cells using the induced pluripotent stem cell (iPSC) technology.
The study, led by the University of Edinburgh's MRC Centre for Regenerative Medicine, paves the way for the creation of a stem cell library that can be used for in vitro hepatic disease models.
GAINESVILLE, Fla. -- University of Florida researchers have grown tumors in mice using cells from inflamed but noncancerous colon tissue taken from human patients, a finding that sheds new light on colon cancer and how it might be prevented.
Cells could be orientated in a controlled way on a micro-patterned surface based upon a delicate material technique, and the orientation could be semi-quantitatively described by some statistical parameters, as suggested by the group of DING from Fudan University, Shanghai, CHINA.
University of Washington (UW) researchers have succeeded in engineering human tissue patches free of some problems that have stymied stem-cell repair for damaged hearts.
Human umbilical cord blood cells may be far more versatile than previous research has indicated. Two independent studies, published by Cell Press in the October 2nd issue of the journal Cell Stem Cell, report that they have successfully reprogrammed human umbilical cord blood cells into cells with properties similar to human embryonic stem cells.
LA JOLLA, CA -- Umbilical cord blood cells can successfully be reprogrammed to function like embryonic stem cells, setting the basis for the creation of a comprehensive bank of tissue-matched, cord blood-derived induced pluripotent stem (iPS) cells for off-the-shelf applications, report researchers at the Salk Institute for Biological Studies and the Center for Regenerative Medicine in Barcelon
Berkeley -- A study led by researchers at the University of California, Berkeley, has identified critical biochemical pathways linked to the aging of human muscle. By manipulating these pathways, the researchers were able to turn back the clock on old human muscle, restoring its ability to repair and rebuild itself.
PITTSBURGH -- Regenerative medicine researchers at the University of Pittsburgh received two grants totaling more than $5 million from the National Institutes of Health (NIH) to explore new methods for cultivating replacement cells from existing tissues and organs.
UCSF researchers have genetically encoded mouse cells to respond to light, creating cells that can be trained to follow a light beam or stop on command like microscopic robots.
MADISON -- A team of scientists from the University of Wisconsin-Madison School of Medicine and Public Health has successfully grown multiple types of retina cells from two types of stem cells -- suggesting a future in which damaged retinas could be repaired by cells grown from the patient's own skin.
PHILADELPHIA -- A tissue-repair-and-regeneration pathway in the human body, including wound healing, is essential for the early lung to develop properly. Genetically engineered mice fail to develop lungs when two molecules in this pathway, Wnt2 and Wnt2b, are knocked out. The findings are described this week in Developmental Cell.
STANFORD, Calif. -- Researchers at Stanford University School of Medicine have discovered, for the first time, a common molecular pathway that is used by both normal stem cells and cancer stem cells when they reproduce themselves.
