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Cells defend themselves from viruses, bacteria with armor of protein errors

When cells are confronted with an invading virus or bacteria or exposed to an irritating chemical, they protect themselves by going off their DNA recipe and inserting the wrong amino acid into new proteins to defend them against damage, scientists have discovered.

Flemish researchers develop revolutionary technology for use in plant breeding

One of the greatest challenges of this century is making the food supply secure in a world that finds itself under increasing pressure from the growing population, changing food patterns and changi

Jumping genes, gene loss and genome dark matter

In research published today by Nature, an international team describes the finest map of changes to the structure of human genomes and a resource they have developed for researchers worldwide to look at the role of these changes in human disease. They also identify 75 'jumping genes' - regions of our genome that can be found in more than one location in some individuals.

Genome-wide study of autism published in Nature

In one of the first studies of its kind, an international team of researchers has uncovered a single-letter change in the genetic code that is associated with autism. The finding, published in the October 8 issue of the journal Nature, implicates a neuronal gene not previously tied to the disorder and more broadly, underscores a role for common DNA variation.

Researcher solves mystery about proteins that package the genome

TALLAHASSEE, Fla. -- A Florida State University College of Medicine researcher has solved a century-old mystery about proteins that play a vital role in the transfer of the human genetic code from one cell to another. The discovery could lead to finding new ways to help the body fight a variety of diseases, including cancer.

Novel polymer delivers genetic medicine, allows tracking

Blacksburg, Va. -- Theresa M. Reineke, associate professor of chemistry in the College of Science, and colleagues in her lab at Virginia Tech and at the University of Cincinnati have developed a new molecule that can travel into cells, deliver genetic cargo, and packs a beacon so scientists can follow its movements in living systems.

In amoeba world, cheating doesn't pay

Cheaters may prosper in the short term, but over time they seem doomed to fail, at least in the microscopic world of amoebas where natural selection favors the noble.

Telltale moss

Hikers know that moss on a tree trunk always points north. According to new research by Israeli and German scientists, this ancient plant may also provide a new "compass" for stem cell research, telling scientists how better to program stem cells for medical purposes.

Junk DNA may prove invaluable in quest for gene therapies

Scientists have identified how a protein enables sections of so-called junk DNA to be cut and pasted within genetic code -- a finding which could speed development of gene therapies.

HIV uses several strategies to escape immune pressure

ATLANTA - A study of how HIV mutates in response to immune system pressure by Emory Vaccine Center researchers shows that the virus can take several escape routes, not one preferred route.

The results are online and scheduled for publication in the September issue of the journal Public Library of Science Pathogens.

Study of huge numbers of genetic mutations point to oxidative stress as underlying cause

CORVALLIS, Ore. -- A study that tracked genetic mutations through the human equivalent of about 5,000 years has demonstrated for the first time that oxidative DNA damage is a primary cause of the process of mutation - the fuel for evolution but also a leading cause of aging, cancer and other diseases.

Open source DNA

In the chilling science fiction movie Gattaca, Ethan Hawke stars as a man with "inferior genes" who assumes another's genetic identity to escape a dead-end future. The 1997 film illustrates the very real fear swirling around today's genome research -- fear that private genetic information could be used negatively against us.

New images capture cell's ribosomes at work

Berkeley - Researchers at the University of California, Berkeley, have for the first time captured elusive nanoscale movements of ribosomes at work, shedding light on how these cellular factories take in genetic instructions and amino acids to churn out proteins.

Evolutionarily preserved mechanism governs use of genes

Researchers at Uppsala University have found that the protein coding parts of a gene are packed in special nucleosomes. The same type of packaging is found in the roundworm C elegans, which is a primeval relative of humans. The mechanism can thereby be traced back a billion years in time, according to the study presented in the journal Genome Research.

Stanford professor sequences his entire genome at low cost, with small team

STANFORD, Calif. -- The first few times that scientists mapped out all the DNA in a human being in 2001, each effort cost hundreds of millions of dollars and involved more than 250 people. Even last year, when the lowest reported cost was $250,000, genome sequencing still required almost 200 people. In a paper to be published online Aug.



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