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New paper describes connections between Circadian and metabolic systems

A paper by University of Notre Dame biologist Giles Duffield and a team of researchers offers new insights into a gene that plays a key role in modulating the body's Circadian system and may also

'Moonlighting' molecules discovered

Since the completion of the human genome sequence, a question has baffled researchers studying gene control: How is it that humans, being far more complex than the lowly yeast, do not proportionall

Why antidepressants don't work for so many

CHICAGO --- More than half the people who take antidepressants for depression never get relief.

Scientists use math modeling to predict unknown biological mechanism of regulation

AUSTIN, Texas -- A team of scientists, led by a biomedical engineer at The University of Texas at Austin, have demonstrated -- for the first time -- that mathematical models created from data obtained by DNA microarrays, can be used to correctly predict previously unknown cellular mechanisms.

UCSD researchers pave the way for effective liver treatments

A combination of bioengineering and medical research at the University of California, San Diego has led to a new discovery that could pave the way for more effective treatments for liver disease.

In this work, the researchers have utilized an array system that can identify the biological components that can lead to or alleviate liver disease.

Pandemic flu can infect cells deep in the lungs, says new research

Pandemic swine flu can infect cells deeper in the lungs than seasonal flu can, according to a new study published today in Nature Biotechnology. The researchers, from Imperial College London, say this may explain why people infected with the pandemic strain of swine-origin H1N1 influenza are more likely to suffer more severe symptoms than those infected with the seasonal strain of H1N1.

CSHL scientists develop new method to detect copy number variants using DNA sequencing technologies

Cold Spring Harbor, N.Y. -- A research team led by Associate Professor Jonathan Sebat, Ph.D., of Cold Spring Harbor Laboratory (CSHL) has developed a sensitive and accurate way of identifying gene copy number variations (CNVs).

2 software tools that improve identification of cancer biomarkers earn certification

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The explosive growth of genomic and proteomic data has ushered in a new era of molecular medicine in which cancer detection, diagnosis and treatment are tailored to each individual's molecular profile.

The ultimate brow lift: HDAC8 in the epigenetic control of skull morhpgenesis

In the July 15th cover story of G&D, a research team led by Dr. Eric Olson at the UT Southwestern Medical Center at Dallas reports that the class I histone deacetylase 8 (HDAC8) enzyme regulates gene expression in the developing vertebrate skull.

Researchers map how staph infections alter immune system

DALLAS -- July 14, 2009 -- Infectious disease specialists at UT Southwestern Medical Center have mapped the gene profiles of children with severe Staphylococcus aureus infections, providing crucial insight into how the human immune system is programmed to respond to this pathogen and opening new doors for improved therapeutic interventions.

A new lead for autoimmune disease

A drug derived from the hydrangea root, used for centuries in traditional Chinese medicine, shows promise in treating autoimmune disorders, report researchers from the Program in Cellular and Molecular Medicine and the Immune Disease Institute at Children's Hospital Boston (PCMM/IDI), along with the Harvard School of Dental Medicine.

Penn study demonstrates new way to boost immune memory

PHILADELPHIA - After a vaccination or an infection, the human immune system remembers to keep protecting against invaders it has already encountered, with the aid of specialized B-cells and T-cells.

Study identifies genes that protect against aging

Scientists at the University of Liverpool have developed a new method to help researchers identify genes that can help protect the body during the ageing process.

Cancer Genomics Browser gives cancer researchers a powerful new tool

SANTA CRUZ, CA--A Cancer Genomics Browser developed by researchers at the University of California, Santa Cruz, provides a new way to visualize and analyze data from studies aimed at improving cancer treatment by unraveling the complex genetic roots of the disease.

Hopkins scientists ID 10 genes associated with a risk factor for sudden cardiac death

One minute, he's a strapping 40-year-old with an enviable cholesterol level, working out on his treadmill.

The next, he's dead.



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