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Vegetable-based drug could inhibit melanoma

Compounds extracted from green vegetables such as broccoli and cabbage could be a potent drug against melanoma, according to cancer researchers. Tests on mice suggest that these compounds, when combined with selenium, target tumors more safely and effectively than conventional therapy.

Dana-Farber oncologists present at ASCO GU -- predict prostate cancer survival using Source MDx test

Dana-Farber Cancer Institute (DFCI) and Source MDx today announced that Source MDx's whole blood RNA transcript-based Precision Profiles(TM) diagnostic test predicted survival in men with castration-resistant prostate cancer (CRPC).

Proepithelin encourages cell growth and migration in prostate cancer

Researchers from Thomas Jefferson University have identified a protein that appears to play a significant role in the growth and migration of prostate cancer cells, especially androgen-independent prostate cancer cells. The study was published in the American Journal of Pathology.

Prostate specific antigen testing may be unnecessary for some older men

Certain men age 75 to 80 are unlikely to benefit from routine prostate specific antigen (PSA) testing, according to a Johns Hopkins study published in the April 2009 issue of The Journal of Urology.

When should prostate-specific antigen testing be stopped?

Although widespread Prostate-Specific-Antigen (PSA) testing has undoubtedly decreased prostate cancer mortality, is there a point of diminishing returns?

Sex, masturbation linked to higher cancer risk

Men who are very sexually active in their twenties and thirties are more likely to develop prostate cancer, especially if they masturbate frequently, according to a study of more than 800 men published in the January issue of BJU International.

How chemo blocks cancer spread

Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth.

Measles Virus May Be Effective Prostate Cancer Treatment

Certain measles virus vaccine strain derivatives, including a strain known as MV-CEA, may prove to be an effective treatment for patients with advanced prostate cancer.

Study Reveals How Cancer-Causing Protein Activates

Researchers at Brown Medical School and Rhode Island Hospital have shed new light on the activation of a protein key to the development of cancers, particularly breast and prostate cancer, the most commonly diagnosed cancers in the United States. The team of cell biologists has discovered a new chemical modification that activates STAT3. This so-called signaling protein is important for embryonic growth and development, helping cells grow, duplicate and migrate. In adulthood, STAT3 presumably falls dormant, but its unexpected and continuous activation causes breast and prostate cells to develop and move through the body.

Component of plastic stimulates growth of certain prostate cancer cells

An estrogen-like chemical commonly used to synthesize plastic food containers has been shown to encourage the growth of a specific category of prostate cancer cell, potentially affecting the treatment efficacy for a subset of prostate cancers. According to a study published in the January 1 issue of Cancer Research, such prostate cancer cells proved to be vulnerable to exposure to the chemical BPA (bisophenol A), an industrial chemical and nonsteroidal environmental estrogen used in the manufacture of food cans, milk container linings, food storage containers and water supply pipes. About 2.5 billion pounds of the chemical are produced each year.

Hormone, Radiation Combo Helps High Risk Prostate Cancer Patients

Prostate cancer patients with high risk cancers who are treated with both internal and external radiation and hormone treatment have a better chance of beating the disease than patients treated with radiation alone, according to a new study published in the January 1, 2005, issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of ASTRO, the American Society for Therapeutic Radiology and Oncology.

Green Tea Polyphenols Thwart Prostate Cancer at Multiple Levels

The polyphenols present in green tea help prevent the spread of prostate cancer by targeting molecular pathways that shut down the proliferation and spread of tumor cells, as well as inhibiting the growth of tumor nurturing blood vessels, according to research published in the December 1 issue of Cancer Research.

Company licenses gov't cancer treatment technology

Patients with cancers previously next to untreatable may have new hope because of a license agreement between Isotron of Norcross, Ga., and UT-Battelle, which manages Oak Ridge National Laboratory. The license allows Isotron to market a treatment called neutron brachytherapy, which enables physicians to deliver a highly concentrated dose of californium-252 neutrons to the site of a tumor instead of having to treat the tumor with conventional gamma rays, which often are not as effective at killing cancer cells. The benefit to patients should be tremendous.

Testosterone deprivation makes men forget

Researchers studying how testosterone deprivation affects verbal memory found that men undergoing the prostate cancer therapy forget things faster than their healthy counterparts. Scientists in a study presented Sunday to the Society for Neuroscience in San Diego found that word retention drops sharply after only two minutes among men undergoing testosterone deprivation therapy. However, initial learning of the words, or encoding, was the same for testosterone-deprived and healthy men, according to the study titled ''Androgen ablation impairs hippocampal-dependent verbal memory processes.''



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