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Spot on treatment for acne

A previously unknown side effect of an unnamed drug currently on the marketplace could be useful for treating acne, reports Chemistry & Industry, the magazine of the SCI. A UK company is about to start a Phase 1 trial with the drug involving 18 healthy human volunteers and the results are expected to be announced later this year. In an earlier Phase 1 study in nine healthy human volunteers, the treatment was seen to reduce the excretion of sebum by the skin, which is associated with acne development, by up to 70%.

‘The Phase I results are startlingly good,’ said Nigel Blackburn, director of clinical development at the company, Summit, which is organising the trial. ‘Reducing sebum production has been the “holy grail” of acne treatment for 30 years, and there has been little success aside from Roaccutane which has significant side effects.’

The current ‘gold standard’ for acne treatment, Roaccutane can cause a wide range of side effects, including teratogenicity – which leads to abonormalities in the unborn foetus of pregnant women, and has also recently been linked to depression and (inconclusively) to teenage suicides. The market for acne treatments is worth several billion dollars, and any new treatment developed without side effects could potentially reap blockbuster sales.

Although Summit has not disclosed the name of the drug now under evaluation, the company says it represents an entirely new class of compounds for treating acne. ‘At the doses we are looking at any side effects should be mild compared with those resulting from Roaccutane treatment,’ Blackburn commented.

The company hopes to begin critical Phase 2 trials to assess the efficacy of the drug in acne sufferers next year. Depending on the results, the drug could either be formulated as a stand-alone topical treatment or more likely in combination with other existing treatments. The company has already been in talks with several interested companies, who are waiting to see whether the initial results can be repeated in a larger study group.

http://sci.mond.org

Submitted by BJS on Mon, 2007-08-13 11:10.

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Acne Scar Removal

Submitted by Anonymous on Wed, 2008-07-23 14:56.

Acne scarring is perhaps worse than the acne itself.

My acne scars weren't horrible. They probably weren't even that noticeable after I put on my foundation. However, I certainly noticed them and that was all it took to bother ME.

If you've got acne scars, you may feel a bit helpless. But you don't have to because there are alternatives to getting rid of acne scars. And you CAN do something about it.

So what do you do about it? Well, there is totally a solution ... actually there are many.

These are NATURAL treatments.

Now, just because you hear the word "natural", I don't want you to shake your head and think you need to just buy some over the counter miracle cream. These remedies WORK! And you'll find that by consistently using them, your acne scars WILL fade just like mine did.

So without further ado, here are my favorite natural acne scar solutions:

Vitamin E
Don't underestimate the power of this healing lotion. You can get it at any drugstore in topical form. I have a HUGE bottle of it under my sink :) . Vitamin E naturally heals scars by moisterizing the damaged skin. Use it everyday to fade away acne scars.

Cocoa Butter
This one should be used carefully. If your acne is not already under control, cocoa butter does pose the threat of additional breakouts. However, if you're using the 3 Day Cure technique and your skin is finally clear, this is a powerful healing tool. Cocoa Butter will soften skin, lighten the scars and make them fade into nothing. I love this one. By the way, Cocoa Butter also works great on fading stretch marks.

Honey
Okay, this is totally gonna change your life! Honey works overtime on acne & acne scars. Yes, Honey! When I first learned about this natural remedy, I was pretty bewildered. The sound of it alone is confusing. Honey is a sticky, sugary substance. How can it possibly clear up skin?

Honey kills bacteria while simultaneously lessens the red look of irritated skin. The acidity in the honey evens out your skin tone, shrinks current pimples and will give your skin a softer feel. Listen, I know you may be skeptical of this solution. I was at first, then I tried it. This natural acne scar remedy works great.

Lemon
Lemon will help clear up acne as well as fade acne scars. Plus your face will smell like a freshly shined harwood floor, so that's a plus ;)

The acidity in the juice will lighten the redness of the scars and balance your skin's pH levels to prevent future breakouts. Give it a shot.

You can find a lot of other natural acne treatments and acne scar treatments by visiting:

http://www.Natural-Acne-Control.com

  • reply

I wonder if it could be some

Submitted by Platypus (not verified) on Mon, 2007-08-13 11:30.

I wonder if it could be some relative of BRL 7660.

  • reply

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