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Caltech researchers explore how cells reconcile mixed messages in decisions about growth

PASADENA, Calif. -- The cells in our body are constantly receiving mixed messages. For instance, an epithelial cell might be exposed to one signal telling it to divide and, simultaneously, another telling it to stop dividing.

Green tea may affect prostate cancer progression

PHILADELPHIA -- According to results of a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research, men with prostate cancer who consumed the active compounds in green tea demonstrated a significant reduction in serum markers predictive of prostate cancer progression.

Gene therapy technique thwarts cancer by cutting off tumor blood supply

University of Florida researchers have come up with a new gene therapy method to disrupt cancer growth by using a synthetic protein to induce blood clotting that cuts off a tumor's blood and nutrient supply.

Colon cancer screening technique shows continued promise in new study

Recent clinical trials show that a new colon cancer screening technique created by Northwestern University researchers has a high enough sensitivity that it could potentially be as or more successful than a colonoscopy in screening for colon cancer.

UNC scientists identify growth factor as possible cancer drug target

CHAPEL HILL, N.C. - To grow and spread, tumors need new blood vessels, a process called angiogenesis. One growth factor that causes angiogenesis has been identified - vascular endothelial growth factor or VEGF - and drugs to inhibit VEGF are already in use. But not all tumors respond to the therapy initially or over the long term.

Gene activity reveals dynamic stroma microenvironment in prostate cancer

HOUSTON -- (June 9, 2009) -- As stroma -- the supportive framework of the prostate gland -- react to prostate cancer, changes in the expression of genes occur that induce the formation of new structures such as blood vessels, nerves and parts of nerves, said researchers at Baylor College of Medicine in a report that appears in the current issue of the journal Clinical Cancer Research.

Women under-represented in most cancer research

Women continue to be under-enrolled in cancer clinical trials, according to a new review, published in the July 15, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society. The study's results suggest that greater efforts are needed to ensure that oncologists know the true effects of treatments and medical procedures in female patients.

Women under-represented in cancer research, U-M study finds

ANN ARBOR, Mich. -- Women are under-represented in clinical cancer research published in high-impact journals, according to a new study by researchers at the University of Michigan Comprehensive Cancer Center.

Jefferson researchers identify critical marker of response to gemcitabine in pancreatic cancer

(PHILADELPHIA) A protein related to aggressive cancers can actually improve the efficacy of gemcitabine at treating pancreatic cancer, according to a Priority Report in Cancer Research, published by researchers at Thomas Jefferson University.

UCLA cancer researchers first to link intestinal inflammation with systemic chromosome damage

UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.

Tumor growth and chemo response may be predicted by mathematical model

The aggressiveness of tumors and their susceptibility to chemotherapy may become easier to predict based on a mathematical model developed at The University of Texas Health Science Center at Houston.

Computer model predicts brain tumor growth and evolution

PROVIDENCE, R.I. [Brown University] ? Researchers from Brown University and other institutions have developed a computational computer model of how brain tumors grow and evolve.

Review finds conflicts of interest in many cancer studies

A new analysis finds that a considerable number of clinical cancer studies published in respected medical journals have financial connections to pharmaceutical companies.

MIT: Targeting tumors using tiny gold particles

CAMBRIDGE, Mass.--It has long been known that heat is an effective weapon against tumor cells. However, it's difficult to heat patients' tumors without damaging nearby tissues.

Now, MIT researchers have developed tiny gold particles that can home in on tumors, and then, by absorbing energy from near-infrared light and emitting it as heat, destroy tumors with minimal side effects.

Genetic variants predict recurrence of bladder cancer, patient survival

DENVER - Scientists at The University of Texas M. D. Anderson Cancer Center have discovered genetic variations in the inflammation pathway that reduce the likelihood of recurrence and increase survival of patients with non-muscle invasive bladder cancer (NMIBC) who are treated with mainstream therapy.



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