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UF researchers find triggers in cells' transition from colitis to cancer

GAINESVILLE, Fla. -- University of Florida researchers have grown tumors in mice using cells from inflamed but noncancerous colon tissue taken from human patients, a finding that sheds new light on colon cancer and how it might be prevented.

Scientists identify common HPV genotypes in northern India, encourage vaccination

BOSTON -- Although a wide spectrum of human papillomavirus is seen across the population of India, HPV-16 and HPV-18 are the most common types and a vaccination targeting these types could eliminate 75 percent of the cervical cancers in the region, according to data presented at the American Association for Cancer Research Frontiers in Basic Cancer Research Meeting.

Leptin linked with more aggressive thyroid cancer in Middle Eastern region

BOSTON -- Leptin, a molecule linked with obesity, may play a crucial role in predicting poor prognosis from thyroid cancer, at least in the Middle Eastern region of the world, according to data presented at the American Association for Cancer Research Frontiers in Basic Cancer Research Meeting.

Survivors of childhood cancer less likely to marry

PHILADELPHIA -- Childhood cancer survivors typically suffer from the long-term effects of cancer treatment on physical health, and results of a new study suggest that social implications also exist, which may affect their chance of an "I do" at the altar.

High-sensitivity bone marrow aspiration technology enhances leukemia cell detection

PHILADELPHIA -- Scientists have created a viable technology to improve the detection of leukemia cells in bone marrow.

Physical activity in adolescence associated with decreased risk of brain cancer in adulthood

PHILADELPHIA -- While little is known about the causes of glioma, researchers at the National Cancer Institute have found that this rare but often deadly form of brain cancer may be linked to early life physical activity and height.

NEDD9 protein supports growth of aggressive breast cancer

Researchers at Fox Chase Cancer Center have demonstrated that a protein called NEDD9 may be required for some of the most aggressive forms of breast cancer to grow. Their findings, based on the study of a mouse model of breast cancer, are presented in a recent issue of Cancer Research, available on-line now.

Lack of social interaction affects health outcomes of breast cancer

PHILADELPHIA -- Social environment can play an important role in the biology of disease, including breast cancer, and lead to significant differences in health outcome, according to results of a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

Women fare better than men with metastatic colorectal cancer -- are hormones helping?

PHILADELPHIA -- Younger women with metastatic colorectal cancer lived longer than younger men. However, this survival advantage disappeared with age, suggesting a benefit from estrogen or other hormones, according to results of a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Obesity hinders chemotherapy treatment in children with leukemia

PHILADELPHIA -- Obesity is an important factor contributing to chemotherapy resistance and increasing relapse rates among children with leukemia, according to recent findings published online first in Cancer Research, a journal of the American Association for Cancer Research.

Diabetes drug kills cancer stem cells in combination treatment in mice

PHILADELPHIA -- In a one-two punch, a familiar diabetes drug reduced tumors faster and prolonged remission in mice longer than chemotherapy alone by targeting cancer stem cells, Harvard Medical School researchers reported in the September 14 online first edition of Cancer Research, a journal of the American Association for Cancer Research.

Diabetes drug kills cancer stem cells in combination treatment in mice

BOSTON, Mass. (September 14, 2009) -- In a one-two punch, a familiar diabetes drug reduced tumors faster and prolonged remission in mice longer than chemotherapy alone, apparently by targeting cancer stem cells, report Harvard Medical School researchers in the Sept. 14 advance online Cancer Research.

University of Hawaii at Manoa CRCH scientists report adulthood body size associated with cancer risk

A team of scientists led by researcher Brenda Hernandez, Ph.D., M.P.H. -- an assistant professor at the University of Hawai'i at Mānoa's Cancer Research Center of Hawai'i -- has reported that body mass in younger and older adulthood, and weight gain between these life periods, may influence a man's risk for prostate cancer.

Lapatinib shows minimal effect against liver cancer

PHILADELPHIA -- Use of the molecularly targeted agent lapatinib to delay tumor growth and improve the survival of patients with inoperable hepatocellular carcinoma, or liver cancer, only benefited certain subgroups of patients.

Autoimmune response can induce pancreatic tumor rejection

PHILADELPHIA -- Immune responses are capable of killing tumors before they can be directed toward normal body tissue, according to new scientific findings published in Cancer Research, a journal of the American Association for Cancer Research.



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