Indiana
A new non-invasive therapy for liver cancer patients who cannot be helped by surgery or organ transplantation is being evaluated by researchers at the Indiana University School of Medicine. The Phase I clinical trial at the IU Cancer Center uses extracranial stereotactic radioablation (SRA) as a potential new treatment for hepatocelluar carcinoma, a cancer that originates in the liver, or for liver metastasis from other sites.
It's virtually impossible for people who use wheelchairs and other mobility devices to enjoy the full benefits of a beach experience, but the National Center on Accessibility at Indiana University Bloomington is working to remedy this situation that affects millions of Americans. "Most typical wheelchairs are impossible to use on sand, so people with disabilities are unable to enjoy the beach," NCA Director Gary Robb explained. "We had about 40 men and women who use wheelchairs test five different wheeled devices designed to traverse beach sand to evaluate their usability. We are now compiling the data and hope to report our findings in two to three months to government agencies, people with disabilities, and others interested in an independent analysis of this equipment."
A compound developed by British scientists early in World War II as a treatment against chemical weapons has value against today's threat of bioterrorism, according to Indiana University School of Medicine researchers at Indiana University-Purdue University Fort Wayne. Researchers studying British Anti-Lewisite provide an overview of its historical uses, development and clinical implications today of the heavy metal chelating agent, detailed in the March issue of the Annals of Emergency Medicine. BAL is a medical therapy to remove metal poisonings from the body.
A major technical advance in astronomy is making it possible for scientists to see individual living cells of the human retina clearly for the first time. This will greatly improve doctors' ability to diagnose diseases of the retina such as glaucoma at an early stage, when intervention and treatment can prevent blindness.
In an effort to help create spacecraft that can think, NASA and a group of six colleges led by Purdue University today are meeting in West Lafayette, Ind., to officially launch the NASA Institute for Nanoelectronics and Computing. Institute scientists and engineers will collaborate to work on methods to make electronics measured in nanometers -- much smaller than today's components. A nanometer is roughly 100,000 times smaller than the width of a human hair. Purdue scientists will work with researchers at Northwestern, Cornell and Yale universities, the University of Florida and the University of California at San Diego.
Coonhound puppies on diets containing the type of fat found in deep-fried foods are furthering understanding of how these fats contribute to aging and development of human diseases such as atherosclerosis and cancer, according to Purdue University scientists. One group of dogs fed a highly-oxidized lipid diet and another group fed one with a moderate level of this fat type, both had reduced growth, bone formation and immune function, said John Turek, Purdue professor of basic sciences. This was the first study in dogs to assess the effects of oxidized lipids on growth, antioxidant status, bone development and immune function.
An environmentally friendly solution to one of the world's most notorious chemical contamination problems may be a step closer to reality, reports a research team from Purdue University and the University of British Columbia. The team has identified one of the key stumbling blocks that prevent microorganisms from decomposing PCBs (polychlorinated biphenyls), a persistent and potentially hazardous industrial chemical that has become nearly ubiquitous in the environment. While capitalizing on the discovery will take time, it could eventually show researchers how to teach microorganisms to break down PCBs into ecologically safe molecules, a process known as bioremediation.
Engineers have developed a new mathematical formula that can spot flaws in automobile designs before they get to the costly assembly line stage. Engineers now use complicated models in which numerous car parts are represented by mathematical expressions that must take into consideration many precise mechanical details. The models have to include information such as the mass of components, their stiffness and dampening characteristics, and the exact forces involved. These models are themselves flawed, the researchers believe, because they rely on approximations about the characteristics and interactions of automotive parts. "A major difference in our method is that we don't use approximations," said one of the Purdue team. "We have found that you don't need to know all of those parameters."
Physicists have devised a new experiment that will be used in the quest for exotic forces in nature and "additional spatial dimensions." The researchers have shown what they say is a new way to measure a phenomenon known as the Casimir effect ? findings that also could have implications for the design of microscopic machines that contain tiny parts on the size scale of nanometers ? or billionths of a meter. The Casimir effect, predicted in 1948 by Dutch physicist Hendrick Casimir, is a force that pushes together two plates of metal placed near each other in empty space ? or a vacuum. The closer the plates are to each other, the stronger the force.
