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UCLA cancer researchers first to link intestinal inflammation with systemic chromosome damage

UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.

HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection

Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress pathway.

Mount Sinai first in US to implant FDA-cleared ring for mitral valve repair

David H. Adams, MD, Marie-Josée and Henry R. Kravis Professor and Chairman of the Department of Cardiothoracic Surgery at The Mount Sinai Medical Center, performed the first two implantations of the Carpentier-Edwards Physio II ring in the United States yesterday. Dr. Adams co-invented the ring, which was cleared by the Food and Drug Administration last month, with Alain F.

Researchers find a new way to potentially thwart anthrax

In a new study, NYU School of Medicine researchers have found what may be an Achilles' heel of deadly anthrax -- a system that the bacteria use to communicate their presence to others of their kind. The researchers, Martin Blaser, M.D., the Frederick King Professor and Chairman of the Department of Medicine, and Professor of Microbiology and graduate student Marcus Jones, describe a "quorum-sensing system" in anthrax that is a type of bacterial "calling card." Disrupting this system may open new avenues to prevention and treatment of anthrax, says Dr. Blaser.



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