member
DURHAM. N.C. - An international study to resolve a decade of debate over the best timing for administering an anti-clotting drug for certain heart patients has come up with an answer: It doesn't matter.
Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress pathway.
FINDINGS: Scientists at the Whitehead Institute for Biomedical Research and the National University of Singapore have discovered the first microRNA (miRNA) capable of directly tamping down the activity of the well known tumor-suppressor gene, p53, While p53 functions to prevent tumor formation, the p53 gene is thought to malfunction in more than 50% of cancerous tumors.
They say a picture tells a thousand stories, but can it also tell how smart you are? Actually, say UCLA researchers, it can.
Stem cells can thrive in segments of well-vascularized tissue temporarily removed from laboratory animals, say researchers at the Stanford University School of Medicine. Once the cells have nestled into the tissue's nooks and crannies, the so-called "bioscaffold" can then be seamlessly reconnected to the animal's circulatory system.
WASHINGTON, DC, March 2, 2009 - One-third of Americans are losing sleep over the state of the U.S. economy and other personal financial concerns, according to a new poll released today by the National Sleep Foundation (NSF). The poll suggests that inadequate sleep is associated with unhealthy lifestyles and negatively impacts health and safety.
Researchers say a newly tested method for producing super dense, defect-free, thin polymer films is the fastest, most efficient method ever achieved and it may dramatically improve microelectronic storage capabilities such as those in computer memory sticks.
Researchers may be able to "freeze" water into a solid, not by cooling but by confining it to narrow spaces less than one-millionth of a millimeter wide, according to new results from an interdisciplinary team of scientists and engineers.
Researchers at the University of North Carolina at Chapel Hill have shown that disruption of the circadian clock - the internal time-keeping mechanism that keeps the body running on a 24-hour cycle -- can slow the progression of cancer.
Researchers searching the depths of space to study gravitational waves may have stumbled on one of the most important discoveries in physics: A holographic universe.
Researchers at the Johns Hopkins University School of Medicine have discovered how a whole class of commonly used chemotherapy drugs can block cancer growth.
A protein developed by scientists at Oregon Health & Science University blocks the growth of glioblastoma, an aggressive and deadly brain tumor, in laboratory rats, a new study shows. Herstatin inhibits the activation of a family of enzymes responsible for signaling inside tumor cells that tells the cells to proliferate and display other malignant properties, said Gail Clinton, Ph.D., professor of biochemistry and molecular biology in the OHSU School of Medicine who co-authored the study appearing this month in the journal Clinical Cancer Research.
Researchers may have made a crucial discovery in the understanding of cellular aging. In a study published in the Nov. 1 issue of the Journal of Clinical Investigation, the researchers report that as cells and tissues age, the expression of two proteins called p16INK4a and ARF dramatically increases. This increase in expression, more than a hundredfold in some tissues, suggests a strong link between cellular aging and the upregulation, or increased production, of p16INK4a and ARF. ''We all know people that we consider to be a young 65, and we believe they won't demonstrate as much p16INK4a or ARF expression as others of the same age.''
Nature can reset the clock in certain types of cancer and reverse many of the elements responsible for causing malignancy, reports a research team led by Whitehead Institute Member Rudolf Jaenisch, in collaboration with Lynda Chin from Dana Farber Cancer Institute. The team demonstrated this by successfully cloning mice from an advanced melanoma cell.
FDA commends the passage by the House of Representatives of S. 741, a bill that includes the Food Allergen Labeling and Consumer Protection Act, as well as the Minor Use and Minor Species Animal Health Act (MUMS). Energy and Commerce Committee Chairman Joe Barton and Ranking Member John D. Dingell were instrumental in moving this bipartisan legislation forward in the House. House approval of the Senate-passed bill represents final Congressional action that clears the way for enactment of this important legislation that will help consumers identify foods that can cause severe allergic reactions and separately that will help create new incentives to develop and seek approval for treatments of diseases in animals, including zoo animals, exotic species and pets.
