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Cigarette smoke may alter immune response in COPD exacerbations

Smoking cigarettes is not only the principle cause of chronic obstructive pulmonary disease (COPD), but it may change the body's immune responses to bacteria that commonly cause exacerbations of the disease, according to new research in a mouse model.

Cellular target may prove useful in treating deadly brain tumors

DURHAM, N.C. - Duke University researchers have identified a receptor on the surface of cells that may give them another avenue of attack against glioblastoma, the most common and most deadly type of brain cancer.

Ali Shilatifard and colleagues aim to clarify the definition of 'epigenetics'

Ali Shilatifard, Ph.D., Investigator, has joined with a team of colleagues to propose an operational definition of "Epigenetics" -- a rapidly growing research field that investigates heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.

Drug commonly used for alcoholism, drug addiction, curbs urges of compulsive stealers

It appears that a drug commonly used to treat alcohol and drug addiction has a similar effect on the compulsive behavior of kleptomaniacs - it curbs their urge to steal, according to new research at the University of Minnesota.

Low-income patients with obstructive sleep apnea are less likely to start CPAP therapy

Westchester, Ill. -- A study in the April 1 issue of the journal SLEEP demonstrates that low socioeconomic status independently predicts the poor acceptance of continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea, and patients with higher incomes are more likely to begin treatment.

Maternal smoking may alter the arousal process of infants, increasing their risk for SIDS

Westchester, Ill. -- A study in the April 1 issue of the journal SLEEP shows that maternal smoking is associated with an impaired infant arousal process that may increase the risk for sudden infant death syndrome (SIDS). The authors suggest that maternal smoking has replaced stomach sleeping as the greatest modifiable risk factor for SIDS.

By shutting down inflammation, agent reverses damage from spinal cord injury in preclinical studies

Washington, DC - Researchers at Georgetown University Medical Center (GUMC) have been able to speed recovery and substantially reduce damage resulting from spinal cord injury in preclinical studies.

Computer simulations explain the limitations of working memory

Researchers at the Swedish medical university Karolinska Institutet (KI) have constructed a mathematical activity model of the brain's frontal and parietal parts, to increase the understanding of the capacity of the working memory and of how the billions of neurons in the brain interact.

Study shows that allergic reactions to Plavix can be treated with steroids and antihistamines

(PHILADELPHIA) - A clinical study of cardiac patients who suffered an allergic reaction to the widely-prescribed drug clopidogrel, also known by the pharmaceutical name Plavix, found that treatment with a combination of steroids and antihistamines can alleviate the allergic reaction symptoms thereby allowing patients to remain on the drug, say doctors from Thomas Jefferson University Hospital.

After heart attack, bone marrow stem cells increase blood flow within heart

Patients treated with their own bone marrow stem cells after a heart attack experienced increased circulation within the heart, a study by Emory University School of Medicine physicians has found.

VAI study rules out transcriptional coactivators as useful herpes antiviral drug targets

Grand Rapids, Mich. (March 25, 2009) - Researchers at Van Andel Research Institute (VARI) have determined that the herpes simplex virus type 1 (HSV-1) does not require transcriptional coactivators for viral gene expression early in the infection process.

New study set to change how critically ill patients are treated

Brussels, 24 March 2009 --- The current practice of intensively lowering blood glucose in critically ill patients increases the risk of death by 10%. Results of the largest trial of intensive glucose lowering in critically ill patients published today in The New England Journal of Medicine indicate that international clinical guidelines need urgent review.

Human adult testes cells can become embryonic-like

WASHINGTON, D.C. - Using what they say is a relatively simple method, scientists at Georgetown University Medical Center have extracted stem/progenitor cells from testes and have converted them back into pluripotent embryonic-like stem cells.

Review of probiotic trial research finds only Bifantis able to claim efficacy for IBS symptoms

CINCINNATI - March 23, 2009 - A review by researchers at Northwestern University (Chicago, IL.) and University of Michigan (Ann Arbor, MI) of the utility of probiotics in the treatment of Irritable Bowel Syndrome (IBS) found that Bifidobacterium infantis 35624 was the only probiotic strain out of 13 different individual strains or preparations reviewed to significantly improve symptoms o

University of Washington scientists one step closer to stopping bone loss during spaceflight

Bone loss in long-duration spaceflight has been identified for decades as a significant problem affecting astronauts.



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