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UnMASCing diseases of the brain

Scientists at the Wellcome Trust Sanger Institute have discovered a set of brain proteins responsible for some of the most common and devastating brain diseases. The proteins underlie epilepsy, depression, schizophrenia, bipolar disease, mental retardation and neurodegenerative diseases including Alzheimer's and Huntington's diseases.

Big boost for global health called for in IOM report

WASHINGTON -- To fulfill America's humanitarian obligations as a member of the international community and to invest in the nation's long-term health, economic interests, and national security, the United States should reaffirm and increase its commitment to improving the health of developing nations, says a new report from the Institute of Medicine.

Quality measures improve outcomes more than hospital volume alone

A new study by researchers at the University of California, San Francisco and Baystate Medical Center at Tufts University in Massachusetts concludes that patients facing coronary artery bypass surgery should, as a first priority, select a medical facility that has the highest adherence to quality standards.

MIT: Climate change odds much worse than thought

CAMBRIDGE, Mass.--The most comprehensive modeling yet carried out on the likelihood of how much hotter the Earth's climate will get in this century shows that without rapid and massive action, the problem will be about twice as severe as previously estimated six years ago -- and could be even worse than that.

Mutant genes in high-risk childhood leukemias identified

A research team has pinpointed a new class of gene mutations, which identify cases of childhood acute lymphoblastic leukemia (ALL) that have a high risk of relapse and death. The finding suggests specific drugs that could treat this high-risk leukemia subtype in children, particularly because such drugs are already in clinical trials for similar blood diseases in adults.

Gene signature helps predict breast cancer prognosis

Vanderbilt-Ingram Cancer Center researchers have uncovered a gene signature that may help predict clinical outcomes in certain types of breast cancer.

Triglycerides implicated in diabetes nerve loss

ANN ARBOR, Mich.? A common blood test for triglycerides ? a well-known cardiovascular disease risk factor ? may also for the first time allow doctors to predict which patients with diabetes are more likely to develop the serious, common complication of neuropathy.

Computer simulation captures immune response to flu

Researchers have successfully tested first the first time a computer simulation of major portions of the body's immune reaction to influenza type A, with implications for treatment design and preparation ahead of future pandemics, according to work accepted for publication, and posted online, by the Journal of Virology.

7 out of 10 women too embarrassed to discuss vaginal dryness and pain with their physician

The majority of post-menopausal women are uncomfortable talking about vaginal dryness and pain and are reluctant to seek medical help, according to results from a new international survey presented today at the European Congress on Menopause in London.

Turmeric extract suppresses fat tissue growth in rodent models

BOSTON (May 18, 2009) Curcumin, the major polyphenol found in turmeric, appears to reduce weight gain in mice and suppress the growth of fat tissue in mice and cell models. Researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (USDA HNRCA) studied mice fed high fat diets supplemented with curcumin and cell cultures incubated with curcumin.

Sodium channel blocker shows promise as a potential treatment for cystic fibrosis

Cystic fibrosis patients may benefit from a new therapy that increases airway hydration, preventing the buildup of mucous, which is a key factor in the disease, according to researchers at Parion Sciences in Durham, N.C.

Study finds genetic links to age of first menstrual period and menopause

Boston, MA -- Newly identified gene variants associated with the age at which females experience their first menstrual period and the onset of menopause may help shed light on the prevention of breast and endometrial cancer, osteoporosis, and cardiovascular disease.

Veterinarians at high risk for viral, bacterial infections from animals

The recent H1N1 influenza epidemic has raised many questions about how animal viruses move to human populations. One potential route is through veterinarians, who, according to a new report by University of Iowa College of Public Health researchers, are at markedly increased risk of infection with zoonotic pathogens -- the viruses and bacteria that can infect both animals and humans.

AIDS patients with serious complications benefit from early retroviral use, Stanford study shows

STANFORD, Calif. - HIV-positive patients who don't seek medical attention until they have a serious AIDS-related condition can reduce their risk of death or other complications by half if they get antiretroviral treatment early on, according to a new multicenter trial led by researchers at the Stanford University School of Medicine.

Genetic marker may predict early onset of prostate cancer

ORLANDO (May 15, 2009)--Fox Chase Cancer Center researchers have identified a genetic marker that is associated with an earlier onset of prostate cancer in Caucasian men who have a family history of prostate cancer. If the data are confirmed, the marker may help clinicians personalize prostate cancer screening.



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