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Hitting where it hurts: Exploiting cancer cell 'addiction' may lead to new therapies

A new study uncovers a gene expression signature that reliably identifies cancer cells whose survival is dependent on a common signaling pathway, even when the cells contain multiple other genetic abnormalities.

Stanford scientists identify molecular powerbrokers involved in cancer's spread

You know the guy -- he's your Facebook friend. The one who knows everyone. Secure at the center of a dense web of relationships, he suggests causes and reconnects old friends like a skilled matchmaker. Scientists have known for some time that biological molecules interact with one another in a similarly complex pattern.

17 million US children live more than an hour away from trauma care

More than 17 million U.S. children live more than an hour away by ground or air transportation from a life-saving pediatric trauma center, according to a new study by researchers at The Children's Hospital of Philadelphia and the University of Pennsylvania.

CU-Boulder study shows 53 million-year-old high Arctic mammals wintered in darkness

Ancestors of tapirs and ancient cousins of rhinos living above the Arctic Circle 53 million years ago endured six months of darkness each year in a far milder climate than today that featured lush, swampy forests, according to a new study led by the University of Colorado at Boulder.

Wiping out the world's mass migrations

Densely packed wildebeests flowing over the Serengeti, bison teeming across the Northern Plains?these iconic images extend from Hollywood epics to the popular imagination. But the fact is, all of the world's large-scale terrestrial migrations have been severely reduced and a quarter of the migrating species are suspected to no longer migrate at all because of human changes to the landscape.

Endless original, copyright-free music

UGR researchers Miguel Delgado, Waldo Fajardo and Miguel Molina decided to design a software programme that would enable a person who knew nothing about composition to create music. The system they devised, using AI, is called Inmamusys, an acronym for Intelligent Multiagent Music System, and is able to compose and play music in real time.

Commonly used medications may produce cognitive impairment in older adults

INDIANAPOLIS - Many drugs commonly prescribed to older adults for a variety of common medical conditions including allergies, hypertension, asthma, and cardiovascular disease appear to negatively affect the aging brain causing immediate but possibly reversible cognitive impairment, including delirium, in older adults according to a clinical review now available online in the Journal of Clini

Study shows gay couples want legal rights, regardless of marriage

New research from North Carolina State University shows that gay and lesbian couples are forming long-term, committed relationships, even in the absence of the right to marry. However, couples surveyed for the study overwhelmingly said they would get married if they could in order to secure legal rights ? such as retirement and healthcare benefits.

Back to normal: Surgery improves outcomes for spine patients

ROSEMONT, Ill.? People with the spine disease called degenerative spondylolisthesis* -- who choose surgical treatment -- experience substantially greater relief from pain over time compared to those who do not have surgery, according to a study published in the June 2009 issue of The Journal of Bone and Joint Surgery (JBJS).

Intervention reduces delinquent teenage pregancy rates

CORVALLIS, Ore. ? A program aimed at reducing criminal behavior in juvenile justice teens has yielded a surprising side benefit. The program is also reducing the teens' rate of pregnancy, according to a new study out this week.

UCLA cancer researchers first to link intestinal inflammation with systemic chromosome damage

UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.

Penn researchers discover genetic risk factor for testicular cancer

(PHILADELPHIA) ? Researchers at the University of Pennsylvania School of Medicine have uncovered variation around two genes that are associated with an increased risk of testicular cancer.

Slicing chromosomes leads to new insights into cell division

ANN ARBOR, Mich.?By using ultrafast laser pulses to slice off pieces of chromosomes and observe how the chromosomes behave, biomedical engineers at the University of Michigan have gained pivotal insights into mitosis, the process of cell division.

Their findings could help scientists better understand genetic diseases, aging and cancer.

Chemotherapy combination outcomes differ for aged, younger colon cancer patients

ORLANDO, Fla.--The combination of chemotherapies 5FU and oxaliplatin compared to 5FU alone after surgery for colon cancer decreases colon cancer recurrence and promotes longer survival for patients under 70 -- but not for those who are older, according to Mayo Clinic and Dana-Farber Cancer Institute scientists who will present their findings at the American Society of Clinical Oncology's (ASCO)

One in ten advanced colon cancer patients worry about prescription drug costs

ORLANDO, Fla.--The vast majority of advanced colon cancer patients in a clinical trial were not concerned about the cost of prescription drugs for managing chemotherapy side effects, such as infection, pain and nausea and few adopted strategies to reduce drug cost burdens after joining the clinical trial, according to a study led by researchers at Dana-Farber Cancer Institute in Boston.



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