Yale
Maternal and newborn outcomes were greatly improved when doctors implemented a series of simple clinical interventions at Yale-New Haven Hospital's obstetrical unit. Yale School of Medicine researchers report their results in the May issue of the American Journal of Obstetrics & Gynecology.
Researchers have determined the structure of a key genetic mechanism at work in bacteria, including some that are deadly to humans, in an important step toward the design of a new class of antibiotics, according to an accelerated publication that appeared online today as a "paper of the week" in the Journal of Biological Chemistry.
A single crafty protein allows the deadly bacterium Salmonella enterica to both invade cells lining the intestine and hijack cellular functions to avoid destruction, Yale researchers report in the April 17 issue of the journal Cell.
Routine screening for coronary artery disease in type 2 diabetes patients with no symptoms of angina or a history of coronary disease is unnecessary and may lead initially to more invasive and costly heart procedures, according to researchers at Yale School of Medicine. They report their findings in the April 15 Journal of the American Medical Association.
Two-year-olds with autism lack an important building block of social interaction that prompts newborn babies to pay attention to other people. Instead, these children pay attention to physical relationships between movement and sound and miss critical social information. Researchers at the Yale School of Medicine report their results in the March 29 online issue of Nature.
New Haven, Conn.--Even in the midst of a growing economic crisis last fall, over 90 percent of Americans said that the United States should act to reduce global warming, according to a national survey released today by researchers at Yale and George Mason Universities.
Yale researchers investigating the genetic causes of blood pressure variation have identified a previously undescribed syndrome associated with seizures, a lack of coordination, developmental delay and hearing loss.
The helpless behavior that is commonly linked to depression and post-traumatic stress disorder (PTSD) is preceded by stress-related losses of synapses--microscopic connections between brain cells--in the brain's hippocampal region, researchers at Yale School of Medicine report in the March 1 issue of Biological Psychiatry.
A popular smoking cessation drug dramatically reduced the amount a heavy drinker will consume, a new Yale School of Medicine study has found. Heavy-drinking smokers in a laboratory setting were much less likely to drink after taking the drug varenicline compared to those taking a placebo, according to a study published online in the journal Biological Psychiatry.
Before flying off the handle the next time someone cuts you off in traffic, consider the latest research from Yale School of Medicine researchers that links changes brought on by anger or other strong emotions to future arrhythmias and sudden cardiac arrests, which are blamed for 400,000 deaths annually.
The movement of facial skin and muscles around the mouth plays an important role not only in the way the sounds of speech are made, but also in the way they are heard according to a study by scientists at Haskins Laboratories, a Yale-affiliated research laboratory.
Prions, infectious proteins associated with bovine spongiform encephalopathy (BSE) or Mad Cow Disease, were previously thought to accumulate mainly in the brain, but Yale and University of Zurich researchers report in Science that other organs can also become infected. Past research had shown that the brain and spinal cord bear the highest infection risk for BSE, followed by organs such as the spleen, lymph nodes and tonsils. All other organs were thought to be devoid of prions.
Adolescents who smoke show impairment of memory and other cognitive functions, according to a Yale study in Biological Psychiatry. More than 4.5 million teenagers smoke cigarettes in the United States, according to the Centers for Disease Control and the U.S. Census Bureau. Leslie Jacobsen, M.D., associate professor of psychiatry and pediatrics at Yale School of Medicine, and her research team tested working memory. This form of memory is used when keeping information in mind and manipulating it. They also evaluated verbal learning and memory, attention, mood, symptoms of nicotine withdrawal and tobacco cravings in 41 adolescent daily smokers and 32 nonsmokers. The groups were similar in age, gender and education.
A toxic chemical painted on the bottom of large vessels to protect against barnacles may cause hearing difficulties in whales and other mammals, according to a study by Yale researchers published in the Biophysical Journal. The chemical tributyltin oxide (TBT) affects the mechanical activity of the outer hair cells, which modulate and boost incoming sound energy to the inner hair cells, according to senior author Joseph Santos-Sacchi, professor of surgery and neurobiology at Yale School of Medicine.
Smoking marijuana is associated with increased risk of many of the same symptoms as smoking cigarettes--chronic bronchitis, coughing on most days, phlegm production, shortness of breath, and wheezing, according to a Yale study published in the Journal of General Internal Medicine. In addition, marijuana smoking may increase risk of respiratory exposure by infectious organisms, such as fungi and molds, since cannabis plants are contaminated with a range of fungal spores, said Brent Moore, assistant professor of psychiatry at Yale School of Medicine and lead author of the study.
