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Studies reveal hepatitis C virus carriers experience substantial increase in mortality

Hepatitis C virus (HCV) is a blood-borne disease that causes inflammation of the liver and to which there is currently no vaccine available.

Intensive glucose control halves complications of longstanding type 1 diabetes

Near-normal control of glucose beginning as soon as possible after diagnosis would greatly improve the long-term prognosis of type 1 diabetes, concludes a study published in the July 27, 2009, issue of the Archives of Internal Medicine, which updates information about the clinical course of type 1 diabetes.

Are we what our mothers ate?

PITTSBURGH, July 21 -- Mothers' health in the days and weeks prior to becoming pregnant may determine the health of offspring much later in life, according to results of studies reported at the annual meeting of the Society for the Study of Reproduction, which takes place July 18 to 22 at the David L. Lawrence Convention Center in Pittsburgh.

Studies shed light on preserving fertility among cancer patients

PITTSBURGH, July 20 -- Cancer treatment has come a long way, leading to a multitude of therapy options and improved survival rates. These successes, however, have created a challenge for young cancer patients since chemotherapy and radiation treatments that often save lives threaten fertility.

Professional lobbyists: Pragmatic operatives or just another partisan resource?

Washington, DC -- The thousands of professional lobbyists working in Washington, DC on issues tend to be professional partisans who mobilize resources for one preferred political party exclusively. So finds a new study which counters the common expectation that lobbyists play both sides of the political field regardless of which party is in the ascendancy.

Children's Hospital of Pittsburgh of UPMC scientists identify enzyme important in aging

PITTSBURGH, July 10 -- The secret to longevity may lie in an enzyme with the ability to promote a robust immune system into old age by maintaining the function of the thymus throughout life, according to researchers studying an "anti-aging" mouse model that lives longer than a typical mouse.

Pitt team finds molecule that regulates heart size by using zebrafish screening model

PITTSBURGH, July 5 -- Using zebrafish, researchers at the University of Pittsburgh have identified and described an enzyme inhibitor that allows them to increase the number of cardiac progenitor cells and therefore influence the size of the developing heart. The findings are described in the advance online version of Nature Chemical Biology.

Irritability should be considered when diagnosing bipolar disorder in children

EAST PROVIDENCE, RI -- A new study from Bradley Hospital and The Warren Alpert Medical School of Brown University, as well as two other institutions, adds to mounting evidence that clinicians consider irritability as a symptom when diagnosing pediatric bipolar disorder.

Zero in on ozone with fluorescent solution that detects harmful molecule in air and body

PITTSBURGH -- Researchers at the University of Pittsburgh have developed a fluorescent substance that glows bright green when exposed to even minute amounts of ozone in the air and in biological samples such as human lung cells.

Traumatic brain injury caused by exposure to explosive blast presents critical challenge

New Rochelle, NY, June 18, 2009 -- Blast-induced traumatic brain injury (TBI) has reached critical levels in modern-day warfare. The current issue of Journal of Neurotrauma focuses on the intensive efforts to develop effective treatment strategies and model systems for studying the cause and effects of explosive blast TBI.

Humans related to orangutans, not chimps, says new Pitt, Buffalo Museum of Science study

PITTSBURGH -- New evidence underscores the theory of human origin that suggests humans most likely share a common ancestor with orangutans, according to research from the University of Pittsburgh and the Buffalo Museum of Science.

Pitt team reports in Nature that unique portion of enzyme fights lung infection

PITTSBURGH, June 17 -- An enzyme known to play a key role in the development of emphysema serves as the first line of defense against bacterial infection of the lung, according to researchers at the University of Pittsburgh School of Medicine. They also found that the antimicrobial activity comes from a small portion of the enzyme that is structurally and sequentially unique in nature.

Much touted 'depression risk gene' may not add to risk after all

Stressful life events are strongly associated with a person's risk for major depression, but a certain gene variation long thought to increase risk in conjunction with stressful life events actually may have no effect, according to researchers funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.

Peculiar, junior-sized supernova discovered by New York teen

In November 2008, Caroline Moore, a 14-year-old student from upstate New York, discovered a supernova in a nearby galaxy, making her the youngest person ever to do so. Additional observations determined that the object, called SN 2008ha, is a new type of stellar explosion, 1000 times more powerful than a nova but 1000 times less powerful than a supernova.

Stable marriage is linked with better sleep in women

WESTCHESTER, Ill. -- Being stably married or gaining a partner is associated with better sleep in women than being unmarried or losing a partner, according to a research abstract that will be presented on Wednesday, June 10, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies.



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