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Barn personnel experience higher-than-average rates of respiratory symptoms

North Grafton, Mass., November 19, 2009 -- The estimated 4.6 million Americans involved in the equine industry may be at risk of developing respiratory symptoms due to poor air quality in horse barns, according to a questionnaire study undertaken earlier this year by investigators at Tufts University's Cummings School of Veterinary Medicine.

Improving university-community research partnerships

Researchers from Tufts University and their community-based colleagues have identified several strategies to improve community-based participatory research (CBPR) partnerships.

Experimental agent reduces breast cancer metastasis to bone

Researchers have reduced breast cancer metastasis to bone using an experimental agent to inhibit ROCK, a protein that was found to be over-expressed in metastatic breast cancer.

Poorly cleaned public cruise ship restrooms may predict norovirus outbreaks

(Boston) -- A team of researchers from Boston University School (BUSM), Carney Hospital, Cambridge Health Alliance and Tufts University School of Medicine, have found that widespread poor complian

Research shows Tai Chi exercise reduces knee osteoarthritis pain in the elderly

Researchers from Tufts University School of Medicine have determined that patients over 65 years of age with knee osteoarthritis (OA) who engage in regular Tai Chi exercise improve physical functio

Older patients with dementia at increased risk for flu mortality

BOSTON (October 27, 2009) -- An epidemiological study on pneumonia and influenza (P&I) in adults age 65 and over reports that patients with dementia are diagnosed with flu less frequently, have sh

College students vote smarter than expected

College students make strategic choices about where to vote, most prefer absentee ballots, and they are especially likely to vote absentee if their homes are in swing states, according to a new Northwestern University study of student absentee voting in the 2008 presidential election.

How to improve vaccines to trigger T cell as well as antibody response

Killed or disabled viruses have proven safe and effective for vaccinating billions worldwide against smallpox, polio, measles, influenza and many other diseases.

But killed or severely "attenuated" vaccines, which are safer than "live" vaccines, have been largely unsuccessful for many non-viral diseases, including illnesses like tuberculosis and malaria.

Silk-based optical waveguides meet biomedical needs

MEDFORD/SOMERVILLE, Mass.--There is a growing need for biocompatible photonic components for biomedical applications -- from in vivo glucose monitoring to detecting harmful viruses or the telltale markers of Alzheimer's. Optical waveguides are of particular interest because of their ability to manipulate and transport light in a controlled manner in a variety of configurations.

Study: Smoking may worsen malnutrition in developing nations

A new study finds that smokers in rural Indonesia finance their habit by dipping into the family food budget -- which ultimately results in poorer nutrition for their children. The findings suggest that the costs of smoking in the developing world go well beyond the immediate health risks, according to authors Steven Block and Patrick Webb of Tufts University.

STAT3 gene regulates cancer stem cells in brain cancer

BOSTON (August 10, 2009) -- In a study published online in advance of print in Stem Cells, Tufts researchers report that the STAT3 gene regulates cancer stem cells in brain cancer. Cancer stem cells have many characteristics of stem cells and are thought to be the cells that drive tumor formation.

Scientists report original source of malaria

Irvine, Calif. -- Researchers have identified what they believe is the original source of malignant malaria: a parasite found in chimpanzees in equatorial Africa.

Skin-like tissue developed from human embryonic stem cells

BOSTON (July 21, 2009) -- Dental and tissue engineering researchers at Tufts University School of Dental Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have harnessed the pluripotency of human embryonic stem cells (hESC) to generate complex, multilayer tissues that mimic human skin and the oral mucosa (the moist tissue that lines the inside of the mouth).

New method may accelerate drug discovery for difficult diseases like Parkinson's

CAMBRIDGE, Mass. (July 13, 2009) -- Whitehead Institute scientists have developed a rapid, inexpensive drug-screening method that could be used to target diseases that until now have stymied drug developers, such as Parkinson's disease. This technique uses baker's yeast to synthesize and screen the molecules, cutting target discovery and preliminary testing time to a matter of weeks.

Of yeast and men: Unraveling the molecular mechanisms of Friedreich's ataxia

MEDFORD/SOMERVILLE, Mass. -- Researchers in human genetics have long known that expansions of GAA repeats -- resulting in this nucleotide triplet repeating hundreds or thousands of times -- cause the most common hereditary neurological disorder known as Friedreich's ataxia. There is no cure for this condition, which damages the nervous system and can result in heart disease.



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