Northwestern University
Blocking or eliminating a specific potassium channel in a small group of brain cells may improve or prevent the symptoms of Parkinson's disease, a debilitating and progressive neurodegenerative disease that afflicts over 1 million people in the United States. In Parkinson's disease, neurons that release dopamine die. The loss of dopamine causes an array of debilitating symptoms that include resting tremor, muscle rigidity and slowed movement. Although the cause of the disease remains uncertain, James Surmeier and colleagues at Northwestern University have discovered a way of potentially lessening the symptoms and progression of the disease. The investigators describe their findings in the March issue of Nature Neuroscience.<
Blocking or eliminating a specific potassium channel in a small group of brain cells may improve or prevent the symptoms of Parkinson's disease, a debilitating and progressive neurodegenerative disease that afflicts over 1 million people in the United States. In Parkinson's disease, neurons that release dopamine die. The loss of dopamine causes an array of debilitating symptoms that include resting tremor, muscle rigidity and slowed movement.
If current and former felons had been allowed to vote, the outcome of as many as seven U.S. Senate races and one presidential election since 1978 might have been altered. Felon disenfranchisement laws, combined with high rates of criminal punishment in the United States, sometimes play a decisive role in elections. This is the finding of a study by sociologists Christopher Uggen, University Minnesota, and Jeff Manza, Northwestern University, reported in the most recent issue of the American Sociological Review.
Using a novel gene therapy approach that boosts the body?s immune system, a researcher has cured cancer in laboratory mice. In experiments reported in the Dec. 15 issue of Cancer Research, Chung Lee and colleagues at the Feinberg School of Medicine at Northwestern University applied the gene therapy technique to render immune cells insensitive to transforming growth factor beta (TGF-beta), a powerful, naturally occurring substance in the body called an immunosuppressor that enables cancer cells to evade surveillance by the immune system. The approach boosted the mice?s immune system, which virtually eliminated cancerous tumors in the animals' lungs and prostate gland.
Among teens in juvenile detention, nearly two thirds of boys and nearly three quarters of girls have at least one psychiatric disorder, a federally funded study has found. These rates dwarf the estimated 15 percent of youth in the general population thought to have psychiatric illness, placing detained teens on a par with those at highest risk, such as maltreated and runaway youth.
Researchers have demonstrated a new high-speed quantum cryptography method that uses the properties of light to encrypt information into a form of code that can only be cracked by violating the physical laws of nature. The method promises security even against information security's greatest foe: the not-yet-invented but still-feared powerful quantum computer, which could break almost any conventional code. The researchers transmitted encrypted data at the rate of 250 megabits per second. Because it uses standard lasers, detectors and other existing optical technology to transmit large bundles of photons, the protocol is more than 1,000 times faster than its main competitor, a technique based on single photons that is difficult and expensive to implement, the researchers say.
Functional magnetic resonance imaging (fMRI) studies of the brain show that despite the decrease in brain activity that naturally occurs in aging, particularly in the language areas of the left frontal lobe, some types of language processing may be performed more efficiently in older individuals.
Smoking may play a dual role in the development of a cancer of the lymph glands called follicular lymphoma -- first causing it to develop and then transforming it into diffuse large cell lymphoma, an aggressive cancer generally associated with a poor prognosis.
