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Maintaining stable weight, even in the obese, reduces heart risks

Gaining 15 pounds or more over several years is the major contributor to progression of risk factors for heart disease and development of metabolic syndrome, while maintaining a stable weight -- even in individuals considered obese -- significantly reduces those risks, according to a study led by a Northwestern University researcher.

Cruise ships -- An alternative to assisted living facilities for the elderly

Living on a cruise ship is a feasible and cost-effective option to assisted living facilities, and the services offered on a cruise ship parallel -- even surpass -- what is provided in senior care facilities, according to a study in the November issue of the Journal of the American Geriatric Society. ''Offering many amenities, such as three meals a day with escorts to meals, physicians on site and housekeeping/laundry services, cruise ship could be considered a floating assisted living facility,'' said Lee Lindquist, M.D., instructor of medicine at Northwestern University Feinberg School of Medicine.

OTC drugs for respiratory infections could save $4.75B annually

Using nonprescription, or over-the-counter, medications to treat common upper respiratory infections could save $4.75 billion a year, according to a new study conducted by researchers from Northwestern University. The study, which was sponsored by the Consumer Healthcare Products Association, demonstrates that the majority of savings from taking OTC medications stems from improving work productivity and reducing unnecessary physician visits.

Researchers pinpoint how false memories are formed

False memories are the controversial subject of hotly contested arguments about the validity of repressed memories that can surface years after a traumatic event and about the credibility of eyewitness accounts in criminal trials. Because memories are imperfect under ordinary circumstances -- forming, storing and retrieving them, with great variations in factors influencing those processes -- it is unlikely that a one-answer-fits-all will settle those controversies soon. But a group of researchers from various disciplines at Northwestern University literally have peered into the brain to offer new evidence on the existence of false memories and how they are formed.

Cells in retina found to behave like soap bubbles

Soap bubbles delight children and the young at heart, but they also have been objects of scientific study for centuries. Operating under the laws of physics, bubbles always try to minimize their surface area, even when many bubbles are aggregated together. Now two Northwestern University scientists have demonstrated that the tendency to minimize surface area is not limited to soap bubbles but extends to living things as well. In a paper published Oct. 7 in the journal Nature, they show that cells within the retina take on shapes and pack together like soap bubbles, ultimately forming a pattern that is repeated again and again across the eye. Gaining insight into these patterns can help researchers understand the interplay between genetics and physics in cell formation.

An Important Step Toward Molecular Electronics

Silicon microelectronics has undergone relentless miniaturization during the past 30 years, leading to dramatic improvements in computational capacity and speed. But the end of that road is fast approaching, and scientists and engineers have been investigating another promising avenue: using individual molecules as functional electronic devices. Now a team of engineers at Northwestern University has become the first to precisely align multiple types of molecules on a silicon surface at room temperature -- an important step toward the goal of molecular electronics.

Under-Recognized Condition Important In Treatment of High Blood Pressure

An under-recognized and usually asymptomatic condition called subclavian artery stenosis -- an obstruction of arteries located under the clavicle, or collarbone -- is important in the diagnosis and treatment of high blood pressure, according to a new study. SS was found in approximately 2 percent of individuals without cardiovascular problems and in 7 percent of those currently under a doctor's care for cardiovascular conditions.

Study shows how consensus is attained in a noisy world

A month before the fall of the Berlin Wall, 70,000 people gathered in the streets of Leipzig, East Germany, on Oct. 9, 1989, to demonstrate against the communist regime and demand democratic reforms. Clearly, no central authority planned this event; so how did all of these people decide to come together on that particular day?

Regulatable gene therapy may advance treatment of Parkinson's disease

Neuroscientists have overcome a major obstacle in gene therapy research. They've devised a method that will safely deliver and regulate expression of therapeutic genes introduced into the central nervous system to treat Parkinson's disease and other neurodegenerative diseases.

Origin of enigmatic Galactic-center filaments revealed

Twenty years ago, astronomers discovered a number of enigmatic radio-emitting filaments concentrated near the center of the Milky Way Galaxy. These features initially defied explanation, but a new study of radio images of the Galactic center may point to their possible source. By combining data from the National Science Foundation's Very Large Array (VLA) and Robert C. Byrd Green Bank Telescope (GBT), astronomer Farhad Yusef-Zadeh of Northwestern University has found evidence that at least some of the filaments spring from the concentrated star-formation regions that populate the Galactic center.

Scientists grow neurons using nanostructures

Scientists have designed synthetic molecules that promote neuron growth, a promising development that could lead to the reversal of paralysis due to spinal cord injury. "We have created new materials that because of their chemical structure interact with cells of the central nervous system in ways that may help prevent the formation of the scar that is often linked to paralysis after spinal cord injury," said one of the lead researchers.

Study suggests difference between female and male sexuality

Three decades of research on men's sexual arousal show patterns that clearly track sexual orientation -- gay men overwhelmingly become sexually aroused by images of men and heterosexual men by images of women. In other words, men's sexual arousal patterns seem obvious. But a new Northwestern University study boosts the relatively limited research on women's sexuality with a surprisingly different finding regarding women's sexual arousal.

Should Memphis Build for California Style Earthquakes?

The federal government is urging Memphis and other parts of the Midwest to adopt a new building code that would make buildings as earthquake resistant as those in southern California, where shaking is much more likely to seriously damage a building. A new study by researchers at Northwestern University, the Reaves Firm in Memphis, and Los Alamos National Laboratory finds that the prescribed measures for the Midwest's New Madrid seismic zone (NMSZ) would cost far more than the damage prevented. The New Madrid seismic zone includes parts of Tennessee, Kentucky, Missouri, Arkansas, Illinois, Indiana, and Mississippi.

Nanotechnology may help overcome current limitations of gene therapy

Scientists from Northwestern University and Argonne National Laboratory have created a hybrid "nanodevice" composed of a "scaffolding" of titanium oxide nanocrystals attached with snippets of DNA that may one day be used to target defective genes that play a role in cancer, neurological disease and other conditions.
The titanium oxide nanocrystals, which are less than a few billionths of a meter in diameter and are the same material used in artificial hips and knees, may provide the ideal means of overcoming current limitations of gene therapy, such as adverse reactions to genetically modified viruses used as vehicles to deliver genes into cells.

Mussels compound may lead to safer, more effective medical implants

Medical implants may soon get better at preventing life-threatening clogs and bacterial infections thanks to an unusual coating that is being developed from mussels, according to researchers at Northwestern University. They have developed a two-sided coating: one side is a sticky glue based on adhesive proteins secreted by mussels, the other is a special repellant. While the sticky side is designed to attach securely to the surface of the implant, the repellant side prevents the build-up of cells and proteins that typically foul implant devices such as cardiac stents, urinary catheters and dialysis tubing.



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