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Scientists take early steps toward mapping epigenetic variability

PROVIDENCE, R.I. [Brown University] -- Brown University and other scientists have taken the first steps toward mapping epigenetic variability in cells and tissues. Mapping the human epigenome, similar to the human genome project in the 1990s, could someday allow for quicker and more precise disease diagnoses and more targeted treatments of many chronic ailments.

Uncovering the secrets of ulcer-causing bacteria

A team of researchers from Boston University, Harvard Medical School and Massachusetts Institute of Technology recently made a discovery that changes a long held paradigm about how bacteria move through soft gels.

A synthetic derivative of the kudzu vine can reduce drinking and prevent relapse

  • Kudzu extracts have been used in Chinese folk medicine to treat alcoholism for about 1,000 years.
  • Daidzin is an anti-drinking substance in kudzu.
  • A synthetic form of daidzin, called CVT-10216, can successfully reduce drinking and prevent relapse in preclinical rodent models.

Postdiagnosis aspirin use reduces risk of dying from colorectal cancer

Regular use of aspirin after colorectal cancer diagnosis may reduce the risk of cancer death, report investigators from Massachusetts General Hospital (MGH), Dana-Farber Cancer Institute and Brigham and Women's Hospital.

Denosumab increases bone density, cuts fracture risk in prostate cancer survivors

Twice-yearly treatment with denosumab, a new targeted therapy to stop bone loss, increased bone density and prevented spinal fractures in men receiving androgen-deprivation therapy for prostate cancer.

Breastfeeding associated with reduced risk of breast cancer among women with family history

Women with a family history of breast cancer appear to have a lower risk of developing the disease before menopause if they have ever breastfed a child, according to a report in the August 10/24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

New discovery brings hope to treatment of lymphatic diseases

LEXINGTON, Ky. (Aug. 10, 2009) − Researchers in the laboratory of Dr. Jayakrishna Ambati at the University of Kentucky have discovered the first naturally occurring molecule that selectively blocks lymphatic vessel growth. In an article in the Aug.

2 lines account for most human embryonic stem cell research, Stanford scholar finds

STANFORD, Calif. -- For the past eight years, scientists who wanted to use federal funds for research on human embryonic stem cells had to restrict their studies to 21 cell lines approved by the National Institutes of Health. But an analysis by a researcher at the Stanford University School of Medicine suggests that only two of those lines have been used routinely.

My First Radio Interview

August 7, 2009 by coglanglab

coglanglab's picture

Should I be excited?

Noninsulin-producing alpha cells in the pancreas can be converted to insulin-producing beta cells

New York, NY, August 6, 2009 -- In findings that add to the prospects of regenerating insulin-producing cells in people with type 1 diabetes, researchers in Europe -- co-funded by the Juvenile Diabetes Research Foundation -- have shown that insulin-producing beta cells can be derived from non-insulin-producing cells in the pancreas.

From nerve roots to plant roots -- research on hereditary spastic paraplegia yields surprises

Sprouting. Branching. Pruning. Neuroscientists have borrowed heavily from botanists to describe the way that neurons grow, but analogies between the growth of neurons and plants may be more than superficial. A new study from the National Institutes of Health and Harvard Medical School suggests that neurons and plant root cells may grow using a similar mechanism.

Health-care reform must respect patient autonomy

BOSTON -- As President Obama and Congress weigh changes in the nation's health care system they must avoid creating a system where physicians are financially motivated to pressure patients into mandated treatments that conflict with their values and needs, two Beth Israel Deaconess Medical Center physicians warn.

Seeing the cosmos through 'warm' infrared eyes

NASA's Spitzer Space Telescope has taken its first shots of the cosmos since warming up and starting its second career. The infrared telescope ran out of coolant on May 15, 2009, more than five-and-half-years after launch, and has since warmed to a still-frosty 30 Kelvin (about minus 406 Fahrenheit).

New in Baby Research

August 5, 2009 by coglanglab

coglanglab's picture

Every year, the Harvard Laboratory for Developmental Studies (of which I am a part) sends out a newsletter to all the parents of the kids have participated in our research studies. For every project conducted in the last year, the lead experimenter (usually a grad student or post-doc) writes up the results in layperson-friendly terms. This year's newsletter was just published.

Violence against mothers in bangladesh associated with health problems in young children

Almost half of Bangladeshi women with young children experience violence from their husbands, and their children appear to have a higher risk of recent respiratory infections and diarrhea, according to a report in the August issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.



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