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Link between erectile dysfunction and obesity explored in obesity and weight management

New Rochelle, NY, August 24, 2009 -- Obese men are at increased risk for erectile dysfunction (ED), likely caused by atherosclerosis-related hypertension and cardiovascular disease, as well as hormonal changes associated with obesity, as described in a timely article published in Obesity and Weight Management, a journalzine published by Mary Ann Liebert, Inc.

More than 1/3 of homeowners in foreclosure suffer from major depression, Penn study shows

(PHILADELPHIA) -- The nation's home foreclosure epidemic may be taking its toll on Americans' health as well as their wallets.

Fatigue related to radiotherapy may be caused by inflammation

PHILADELPHIA -- Patients who experience fatigue during radiotherapy for breast or prostate cancer may be reacting to activation of the proinflammatory cytokine network, a known inflammatory pathway, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Newly discovered mechanism in cell division has implications for chromosome's role in cancer

PHILADELPHIA -- "A biologist, a physicist, and a nanotechnologist walk into a ..." sounds like the start of a joke. Instead, it was the start of a collaboration that has helped to decipher a critical, but so far largely unstudied, phase of how cells divide.

How to make a lung

PHILADELPHIA -- A tissue-repair-and-regeneration pathway in the human body, including wound healing, is essential for the early lung to develop properly. Genetically engineered mice fail to develop lungs when two molecules in this pathway, Wnt2 and Wnt2b, are knocked out. The findings are described this week in Developmental Cell.

Vision researchers see unexpected gain a year into blindness trial

GAINESVILLE, Fla. -- Scientists have discovered that even in adults born with extremely impaired sight, the brain can rewire itself to recognize sections of the retina that have been restored by gene therapy.

Vision improvement after gene therapy maintained at 1 year for inherited retinal blindness

PHILADELPHIA -- One year after a trio of young adults received gene therapy for an inherited form of blindness, researchers have documented that the patients are still experiencing the same level of remarkable vision improvements previously measured within weeks.

New class of compounds discovered for potential Alzheimer's disease drug

PHILADELPHIA -- A new class of molecules capable of blocking the formation of specific protein clumps that are believed to contribute to Alzheimer's disease pathology has been discovered by researchers at the University of Pennsylvania School of Medicine.

Yerkes researchers propose ambitious new strategies for AIDS vaccine research

Researchers at the Yerkes National Primate Research Center, Emory University, believe conventional vaccine strategies should not be the only avenue explored in the development of an effective AIDS vaccine.

Penn researchers show that protein unfolding is key for understanding blood clot mechanics

PHILADELPHIA - Fibrin, the chief ingredient of blood clots, is a remarkably versatile polymer. On one hand, it forms a network of fibers -- a blood clot -- that stems the loss of blood at an injury site while remaining pliable and flexible.

Challenging conventional wisdom: advances in development reverse fertility declines, says Penn study

PHILADELPHIA -- A team of researchers at the University of Pennsylvania and the Università Bocconi in Milan have released a study that challenges one of the most established and accepted standards in the social sciences: Human fertility levels tend to decline as countries advance towards high levels of social and economic development.

Cooling treatment after cardiac arrest is cost-effective, Penn study shows

(PHILADELPHIA) -- A brain-preserving cooling treatment called therapeutic hypothermia is a cost-effective way to improve outcomes after out-of-hospital cardiac arrest, which claims the lives of more than 300,000 people each year in the United States and leaves thousands of others neurologically devastated.

Cooling therapy for cardiac arrest survivors is as cost-effective as accepted treatments

Cooling unconscious cardiac arrest survivors can increase survival and has a cost effectiveness comparable to other widely accepted treatments in modern health care, researchers report in Circulation: Cardiovascular Quality and Outcomes.

Fox Chase finds that lung cancer patients respond to erlotinib following cetuximab therapy

SAN FRANCISCO (August 1, 2009) -- Non-small cell lung cancer patients who have progressed on a cetuximab-containing regimen may respond to erlotinib, Fox Chase Cancer Center researchers reported today at the annual meeting of the International Association for the Study of Lung Cancer.

Diabetes gene raises odds of lower birth weight

Pediatric researchers have found that a gene previously shown to be involved in the development of type 2 diabetes also predisposes children to having a lower birth weight. The finding sheds light on a possible genetic influence on how prenatal events may set the stage for developing diabetes in later childhood or adulthood.



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