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News in red and blue: Messages about social factors and health can backfire

ANN ARBOR, Mich. -- Here's a health idea that Democrats and Republicans agree on: when given information on the genetic factors that cause diabetes, both parties equally supported public health policies to prevent the disease.

Loss of tumor-suppressor and DNA-maintenance proteins causes tissue demise

PHILADELPHIA - A study published in the October issue of Nature Genetics demonstrates that loss of the tumor-suppressor protein p53, coupled with elimination of the DNA-maintenance protein ATR, severely disrupts tissue maintenance in mice. As a result, tissues deteriorate rapidly, which is generally fatal in these animals.

Experts summarize state of the science in autism disorders

Scientific understanding and medical treatments for autism spectrum disorders (ASDs) have advanced significantly over the past several years, but much remains to be done, say experts from the Center for Autism Research at The Children's Hospital of Philadelphia who published a scientific review of the field today.

Suppressing a gene in mice prevents heart from aging, preserves its function

Scientists prevented age-related changes in the hearts of mice and preserved heart function by suppressing a form of the PI3K gene, in a study reported in Circulation: Journal of the American Heart Association.

Scientists encouraged by new mouse model's similarities to human ALS

St. Louis, Oct. 9, 2009 -- A new mouse model of amyotrophic lateral sclerosis (ALS) closely resembles humans with the paralyzing disorder, researchers at Washington University School of Medicine in St. Louis report.

Specialty hospitals cherry-pick patients, exaggerate success, says INFORMS meeting paper

Although many specialized hospitals deliver better and faster services in cardiac care and other specialties, a paper being presented at the annual meeting of the Institute for Operations Research and the Management Sciences (INFORMS®) maintains that these hospitals cherry-pick patients to achieve these results, and that average patients actually receive worse care.

Penn study asks, protection or peril? Gun possession of questionable value in an assault

PHILADELPHIA -- In a first-of its-kind study, epidemiologists at the University of Pennsylvania School of Medicine found that, on average, guns did not protect those who possessed them from being shot in an assault. The study estimated that people with a gun were 4.5 times more likely to be shot in an assault than those not possessing a gun.

Pitt researchers net $5 million from NIH to explore better ways to grow cells

PITTSBURGH -- Regenerative medicine researchers at the University of Pittsburgh received two grants totaling more than $5 million from the National Institutes of Health (NIH) to explore new methods for cultivating replacement cells from existing tissues and organs.

Use of statins favors the wealthy, creating new social disparities in cholesterol

PHILADELPHIA -- Since the introduction of statins to treat high cholesterol, the decline in lipid levels experienced by the wealthy has been double that experienced by the poor.

Genes controlling insulin can alter timing of biological clock

Many of the genes that regulate insulin also alter the timing of the circadian clock, a new study has found.

Gene screen reveals 2-way communication between common biological pathways and body's daily clock

PHILADELPHIA -- While scientists have known for several years that our body's internal clock helps regulate many biological processes, researchers have found that the reverse is also true: Many common biological processes -- including insulin metabolism -- regulate the clock, according to a new study by investigators at the University of Pennsylvania School of Medicine, the Genomics Institut

Inner workings of molecular thermostat point to pathways to fight diabetes, obesity

PHILADELPHIA -- Best known as the oxygen-carrying component of hemoglobin, the protein that makes blood red, heme also plays a role in chemical detoxification and energy metabolism within the cell. Heme levels are tightly maintained, and with good reason: Too little heme prevents cell growth and division; excessive amounts of heme are toxic.

Even in a safety net health system, colorectal cancer screening disparities remain

PHILADELPHIA -- Colorectal cancer screening rates are much lower among those in a safety net health system compared to the national average, and the number one predictor of screening is a combination of regular visits and insurance access.

Breakthrough in bubble research at Bath

A researcher from the University of Bath has found a new approach to an old geometric problem of modelling the most efficient way of packing shapes to form a foam.

The discovery is not only making waves in the mathematical world, but could also lead to medical advances in creating hip replacements and replacement bone tissue for bone cancer patients.

Hoover's pro-labor stance helped cause Great Depression, UCLA economist says

Pro-labor policies pushed by President Herbert Hoover after the stock market crash of 1929 accounted for close to two-thirds of the drop in the nation's gross domestic product over the two years that followed, causing what might otherwise have been a bad recession to slip into the Great Depression, a UCLA economist concludes in a new study.



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