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In first, scientists regenerate optic nerve
For the first time, scientists have regenerated a damaged optic nerve -- from the eye to the brain. This achievement, which occurred in laboratory mice and is described in the March 1, 2005 issue of the Journal of Cell Science, holds great promise for victims of diseases that destroy the optic nerve, and for sufferers of central nervous system injuries. "For us, this is a dream becoming reality," says Dr. Dong Feng Chen, lead author of the study, assistant scientist at Schepens Eye Research Institute and an assistant professor of ophthalmology at Harvard Medical School. "This is the closest science has come to regenerating so many nerve fibers over a long distance to reach their targets and to repair a nerve previously considered irreparably damaged."
This research, which has been supported in part by grants from the National Institutes of Health, the Department of Defense and the Massachusetts Lions Club, has always been a priority of the institute, but in recent times, urgency around it has increased, according to Dr. Michael Gilmore, director of research at Schepens Eye Research Institute and professor of ophthalmology at Harvard Medical School. In addition to the thousands of Americans blinded by glaucoma and injuries that destroy the optic nerve, and hundreds of thousands disabled by spinal cord injuries, "we were hearing stories of soldiers in the Middle East whose lives were saved by body armor, but who were returning with severe damage to limbs and eyes," he says. "At the same time, we learned of the untimely death of Christopher Reeves. It was, therefore, a priority for us to redouble our efforts to find ways to restore damaged nerves."
According to Senator John Kerry, who supported funding of this important work, "Schepens is doing cutting-edge research that can make a real difference for a new generation of troops returning home with nerve damage. We need to support our troops in actions, not just words, and I am glad that we have been able to get funding for this important work." Adds Congressman Lynch, "Last month, I visited the Walter Reed Army Medical Center in Washington and met with dozens of service men and women who could benefit directly from the good work of the people at Schepens. Their vital research will not only enhance the lives of our soldiers but also gives hope to every American who suffers from diseases of the central nervous system."
Many tissues in the body continually renew themselves if injured. However, this is not true for nerve cells or their fibers (axons) in the Central Nervous System (CNS). The CNS consists of the brain (of which the eye and optic nerve are part) and the spinal cord. For all mammals, including human beings, CNS nerves lose their ability to regenerate after injury at the point in their development when they are fully formed. For example, the optic nerve loses this ability shortly before birth. So for those afflicted by glaucoma, which destroys the optic nerve through excessive internal pressure, or with injuries that sever the optic nerve after that developmental milestone, destruction can be permanent and blinding.
Chen and her research team have dedicated themselves to learning the reasons why CNS tissue stops regenerating and to finding ways to reverse that process, using the optic nerve as their research model. The optic nerve, which connects the eye to the brain, consists of millions of nerve cells, which, when uninjured, transmit visual information from the retina to the brain for interpretation
In earlier research, Chen's team discovered several processes that they believed "locked up" the optic nerve's ability to regenerate. The first lock, they found, was the turning off of a specific gene -- BCL-2 -- which, when turned on, activates growth and regeneration. The second lock, they theorized, was a scar on the brain created shortly after birth by "glial" cells. (glial cells have many functions in the brain, one of which is to create this kind of scar tissue). The researchers believed that the scar puts up a physical as well as molecular barrier to regeneration. Although there may be other "locks" to the regeneration door, Chen and her colleagues believed these two were the most important.
In the current research, Dr. Kin-Sang Cho, research associate in Chen's laboratory and the first author of the paper, tested two keys to unlock regeneration. The first key involved the development of a mouse model in which the BCL-2 gene is always turned on (or is overexpressing). The second key was the use of a mouse line carrying mutations of "glial specific genes" that lead to the reduced "glial scar" formation.
By unlocking the regeneration with the first key, for the first time, they observed robust optic nerve regeneration in postnatal mice, which nerves grew rapidly and reached from the eye to the brain in four days. But the regeneration happens only in the younger mice whose brains had not yet formed a "glial scar." In the mice that were slightly older and had developed the "glial scar," regeneration failed again.
Dr. Cho then added the second key by combining BCL-2 overexpresser with the "glial gene" mutation to prevent the development of the "glial scar" in the older transgenic mice. He found that the combination of the turned-on BCL-2 and the mutation of "glial specific genes" caused the optic nerves to return to an embryonic state and stimulated rapid, robust regeneration of the optic nerve -- again, as with the younger mice -- within only a few days.
"We could see that at least 40 percent of the optic nerve had been restored," says Chen, "but we believe that an even higher percentage actually regenerated."
The next step for Chen and her colleagues is to determine if the regenerated optic nerves were functional. In other words, did they cause the mice to see again?
Chen also believes that this combination BCL-2 and scar prevention technique could work to regenerate other Central Nervous System tissue, increasing the possibility that spinal cord patients could walk or move again.
This work has important implications. "The possibility of restoring sight following optic nerve injuries is tremendous. Fifteen percent of all wartime injuries include the eye and those with optic nerve trauma are the most grave. Today's medicine has little effective treatment to offer and blindness is often the end result," says Retired Lieutenant Colonel Robert C. Read of the Clinical Applications Division at the Department of Defense's Telemedicine and Advanced Technology Research Center.
"This outstanding breakthrough by Schepens scientists offers new hope to those who suffer from blinding diseases and injuries, including our returning soldiers. The potential application of this discovery to treatments for other central nervous system injuries is yet another reason why I have been proud to support the Department of Defense's funding of the Center for Excellence in Military Low Vision Research," stated Congressman Mike Capuano.
Adds Congressman Stephen F. Lynch, "This extraordinary breakthrough demonstrates what we can achieve when we support public and private partnerships between the Defense Department and the best researchers and scientists in the field. Because of the decades of work and progress by Dr. Gilmore and Dr. Chen and the entire team at the Schepens Eye Research Institute, the search for a way to repair nerve damage in the human body has taken a giant leap forward."
"I'm so pleased with the work going on at Schepens," Rep. Jim McGovern says. "They are on the frontiers of research that will dramatically improve people's lives. And the Federal Government must continue to be a partner in this vital effort."
To obtain a copy of the study, "Reestablishing the Regenerative Potential of the Central Nervous System Axons in Postnatal Mice," email Patti Jacobs at: pjacobs12@comcast.net pjacobs12@comcast.net
Schepens Eye Research Institute is an affiliate of Harvard Medical School and the largest independent research institute in the world.
Submitted by BJS on Thu, 2005-02-24 09:13.
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Optic nerve injury
I had an accident on Feb-08-2008 and there is a loss of vision on my right eye. The eye doctor said that there is an injury in my optic nerve due to the Zygomatic bone fracture. Please inform me if there is any treatment available. My mail id is joscollin@gmail.com
Thanks,
Jos Collin
Optic Atrophy
My husband was in a Bulldozer rollover in which pinched his optic nerve somehow and from this he sustained Optic atrophy in both eyes. We are aware that the optic nerve is unable to regenerate on its own, however we are wondering when Clinical trails we be carried out at Schepens Eye Research Institute and what the criteria for being a participant in the study
optic nerve damage
i've got an head injury on dec
'07 , suddenly my vision was lost on my right eye, i've taken some
treatment in an eye hospital, they done a surgery for optic nerve
decompression after 10 days from the date i've injured , they told
that the vision cannot be recovered, please let me know if anyone get any
treatment that can be done to get my vision back. please give me some
suggestions .
f anyone has information on this would you please email me at rajeshcbe06@gmail.com
HpQGVcRDFKpRHCCRk
my girl crazy, man!
HpQGVcRDFKpRHCCRk
my girl crazy, man!
HpQGVcRDFKpRHCCRk
my girl crazy, man!
Eye Recovery
My dad who is 63 year old has lost both his eye vision....i consulted many doctor but got no answer..optic nerve damage problem..Please contact me at raghu_p_h@yahoo.co.in if any one gets doctor who brings back my dad eyesight....My big dream in life is to get back my dad eye vision...Am thankful for this wonderful site and forum discussion room......
There is nothing impossible.....
hi Sofia....
My dad is also facing the same problem.....he has lost is both eyes recently....He has only problem with optic nerve damage...my big dream of life is to to get back my fathers eye....Am struggling hard to get any Eye specialist....Once i get right doctor i will mail.....You to mail me if you get such a doctor.....Please grop a mail at raghu_p_h@yahoo.co.in
Am from Karnataka,India...how abt you....
hi Sofia....
My dad is also facing the same problem.....he has lost is both eyes recently....He has only problem with optic nerve damage...my big dream of life is to to get back my fathers eye....Am struggling hard to get any Eye specialist....Once i get right doctor i will mail.....You to mail me if you get such a doctor.....Please grop a mail at raghu_p_h@yahoo.co.in
Am from Karnataka,India...how abt you....
optic nerve regeneration
My name is Muhammed. I am a 22 year old male. I Lost vision in my right eye due to a car accident in 2003. Doctors have told me i have damage to the optic nerve. "Nothing more can be determined at this time." I have heard this sentence over and over again so many times that it keeps lingering in my head at every decision i make in my life that involves vision in any way. My faith and hope are still alive. This sounds promising. Please let me know if there is anything that can help me. My email is f22@hotmail.com. Thank you for bringing hope to people's lives in this manner.
Tramatic Optic Neuropathy
My name is byron and i am 19 years old and about two months ago i was in a rollover accident and got 6 skull fractures and a hymatoma and lost my vision in my right eye. the eye doctor says that i will never get my vision back because i have Tramatic Optic Neuropathy. it would mean the world to me to get my right eye back. please give me a call on my cell phone if there is anything that can be done to get my vision back.
970-270-3028
or email me at byronawist@hotmail.com
HELP..... OPTIC NERVE DAMAGE
Hi Doc.
my son lost his vision in a motorbike accident. doctors arenot very clear about the cause of this loss of vision. he has gone through prefrontal surgery and post operative he was unable to see.reports say that his optic nerve is FIRED
is ther any way that any surgery can help him to get his vision back. in case there is hope pl. let me know on jyotiz@yahoo.co.in
optic nerve damage during triple by pass surgery
I had a heart attack in 2004. the doctor advised me that i needed triple by pass surgery in order for me to save my life. I had the surgery, I lived, however, i am now blind. The doctor damaged my optic nerve because not enough oxygen went to my brain during surgery. I was left blind. I never got married or able to have children. I am hoping to someday see again so I can see my family and nephews and nieces. Please help me and many other people with the same condition. I live in Los Angeles county. Do you have someone you can refer me too that can help me? Please email me on zippi252004@yahoo.com. Thank You, gloria sosa
Optic nerve damage during surgery
I had a brain tumour resting upon my optic nerve which distracted my vision. I was advised by my a neurologist to get it removed, I agreed and underwent the surgery. During surgery the neurosurgeon damaged my optic nerve which gas left me completely blind for over 13 years now. I last saw my sons when they were 9 and 13 yrs of age. They are 22 and 27 with kids of they own. My dream is to recieve my sight again, just to enjoy the simple things in life, seeing my family, looking at the sea, beautiful scenery and how technology as increased over the years. Please make my dreams and many other people on this forum dreams possible, God has blessed you with the gift of wisdom, use it to help others in need and you will be blessed further in your career and personal lives. If you need me to be a volunteer to conduct this technology on I am more than willing. There is no risk to great that God cannot handle. Please email me on pgminv@gmail.com. God bless
Caveat Emptor
This area is rife with fraud. Bottom line, I know, I'm a neuro opthamologist, that there has never been a case of regenerating central nervous tissue- particularly a basal ganglion like the optic nerve. The research is going very well, but it's still research.
I can well understand your feelings and know that I would cut off my right arm if it could help cure my child. The problem is that the hucksters know this too, and will tell you what you want to hear.
While definitely worth keeping up with, I would also worry that focusing on regeneration too much might prevent your son from being actively engaged at this very critical, formative period. I wish you the best.
MDDM4@AOL.COM Optic Nerve Damage
My son is now 14 years old. When he was 12 He had a Brain tumor that damaged the optic nerve in both eyes. He is blind in his right eye and has loss in his left eye. Is there anything out there that can help him? We are desperate for a cure. If you can help us email us. Thank You!
Optic Neuritis/Optic Nerve Regeneration
My husband was diagnosed with Optic Neuritis back in 92. He went completely blind in that eye, despite efforts with IV steriods. They did every test imaginable. MRIs were negative for lesions or other abnormalities. At that time we were told it could be something as simple as a virus (like a chicken pox virus) that attacked the optic nerve, or that we were potentially looking at a diagnosis of MS some day, possibly 5, 10, 15 or more years down the road. Doctors couldn't say. Although he has had no more remarkable symptoms, requiring further testing, we live with the fear of this happening to the other eye at any time, and for any reason. I am so happy to see positive research on this. I know he would be very interested in participating in any kind of study of this kind to potentially restore the nerve. Please keep us posted at BruceAndDeb@gmail.com
Looking for Help, for my 8yr Daughter!
My 8 yr old daughter has permanent optic nerve damage from an injury that she had when she was 2 yrs old. I am looking to see if any one has any information about optic nerve regeneration. Have they begun research on human eyes? Please help, she constantly tells her dad that she wonders what it would be like to see with to eyes. It breaks my heart to hear her sometimes! Any information please email me to jncuellar@msn.com. Thank you!
PLEASE HELP MY WIFE, FROM HER HUSBAND & KIDS
MY WIFE JUST WENT THROUGH A BRAIN TUMOR SURGURY. DURING CHEMO & RADITATION,( MABEY DUE TO OTHER FACTORS ALSO ) MY WIFE LOST HER VISON IN BOTH EYES. MY WIFE NOW HAS OPTIC EYE NERVE DAMAGE. SHE CAN STILL SEE LIGHT & MAKE OUT SOME SHADOWED GRAY OBJECTS.
MY LIFE HAS COMPLETELY CHANGED, TRYING TO WORK, RAISE TWO KIDS, TAKE CARE OF MY PARENTS & TAKE CARE OF MY WIFE & KEEP SOMEONE WITH. SHE NEEDS SOMEONE WITH HER MOST OF THE TIME. MY WIFE IS 45 & ALL SHE EVER WANTED WAS TO TAKE CARE OF HER FAMILY & SEE HER KIDS GROW UP.
DR.DONG FENG CHEN AT THE SCHEPENS EYE RESEARCH CENTER WOULD YOU PLEASE CONSIDER MY WIFE FOR YOUR TREATMENT ON OPTIC EYE NERVE DAMAGE.
PLEASE E-MAIL AT JROYALS172@AOL.COM OR CALL 334-207-9055
THANK-YOU MARK
looking for help
My daughter has optic nerve atrophy, presumed stable, possible injury in icu at birth. Misdiagnosed until age 10. Talk about frustrating, knowing something is wrong and you cant figure out why. Currently seen by pediatric neuroopthalmologist at Vanderbilt Univ. Would love to do anything to help find a cure. ozziesapples@dishmail.net
any news?
Hello all. My 33 year old sister has been blind for 13 years due to optic nerve damage. News like this is extremely encouraging. Does anyone have any new news, updates, or general good info. on optic nerve regeneration? If so, please e-mail k-1329@hotmail.com. Thanks and please vote for candidates that support research!
Hope
Dr Chen, I hope you are succeeding in your work. It is giving hope to so many. We are in the Uk and were told today that there was no hope for optic nerve repair so I found the information on your work very uplifting. Please keep trying. gs@artlook.co.uk
optic neuritis
I read your story and it is very similar to mine. In 1993 I had optic neuritis and was given predisone a couple of days later. I had an mri a spinal tap an a few other tests and they were all negative. I had some more problems with the eyes in the next couple of years and went threw all the tests again and they were still negative.
In 2005 i had some pressure in the eye again with tingling all over my body. I went for the same battery of test and this time my mri showed a couple of lesions on my brain and spine. My spinal tap was also irregular and another test called evoked potentials was done and it was also positive. I was diagnosed with multiple sclerosis.
I suggest that you see an MS specialist. The first symptom (most common)of MS is optic neuritis. I am doing well and on medication and wish I had been on the medication earlier and given an iv steroid immediatly.
I hope this info helps you.
My 13 yr. old daughter was
My 13 yr. old daughter was diagnosed with a brain tumor at 6 months old, because of this she has had a lot of atrophy to the optic nerve. She is blind in her right eye, limited depth perception and periferal vision and her good eye has slightly deteriorated. She is learning braille just in case. Now that she is getting older the thought of losing her eyesight is a scary for her. Please,please let me know if something comes out of this research.Thank you so much! ketcha68@msn.com
Loss of vision
I live in the UK.
I have gradually lost the vision in my right eye over the past six months. I am now only able to make out shapes and cannot see any detail. My eye does not respond well to light and I cannot read when closing my better eye.
I have recently noticed over the past two weeks that my left eye is starting to deteriorate in the same manner as my right eye.
I am currently being seen by an eye consultant in the UK. The consultant is unable to determine exactly what is causing my problem. I have had many bloood tests and I have had an MRI scan, all came back ok.
I have read many articles posted on the internet and, although my condition has not been diagnosed it is very similar to NAION.
I would welcome any information and devlopment of possible treatment.
As like any dibilitating health problems to your personal health, you don't fully appreciate how your life changes or is about to change until it actually happens.
I wish you every success for trials.
Is there any reseach of this type currently being carried out in the UK?
kind regards
Robert
blindness
My son had a TBI in 2006. Due to the swelling on his brain he was left blind. If there is any help for people like him we would love to have him see again. He is 21 years old
optic nerve damage
Hi! I am 28 years old and I lost my left eye vision after a brain tumor operation back in 2005. The tumor was attached to the left optic nerve. I had some vision on that eye prior to the surgery, but lost it completely after. The doctors said there's nothing else they could do about it. This research
has really given me hope. If there's anyone who could tell me more about research on optic nerve
regeneration, please reply.
Thank you so much.
Katya
BILATERAL OPTIC ATROPHY
My children both suffer from bilateral optic atrophy, my son is devastated at the fact that he wont ever be able to drive, all his friends are now driving, its also having the same effect on my daughter. If there are any trials they could participate in, or research that they could be involved with on optic nerve regeneration they would be more than willing to volunteer, please e-mail me on :-
paulkempster@fpswales.com Thank you,Paul.
optic nerve regeneration
My father lost his vision in his right eye and can see maybe 2 feet max and what he can see is like looking through a negative from optic nerve damage due to a motorcycle accident 6 years ago. I am writing in search of hope like i read in the research and like so many others who posted a responce which i pray for all of you like my father to someday see normal enough to function again. Last night i received a phone call from my step mother who cried to me and wanted to let me know she is looking to put my father in a rest home. Taking care of him has took a toll on her medically, mentally, and physically to where she can't do it anymore. So here i am looking for a chance of hope to prevent him going to a rest home at 60years old. Any info on doctors over seas or anywhere who can attempt something would be greatly appreciated. Thank you, Gary Wardlord@brightok.net or 580-657-2662
non-arterictic optic ischemic nerophathy
Yes, I'm interested in information or being in a clinical trail. Both of my eyes have optic nerve damage. I've lost most of my sight, been hit by a car and struggle daily to get by. My life has been turn upside down. notify me at roger.allen@ga.usda.gov or rogerallen@alltel.net
Optic Nerve Atrophy
Hi
My father had his sudden loss of vision during his twenties (during 1968) and due to lack of technology advancement he was operated manually which resulted in loss of vision in his left eye and partial vision in his right eye. With his partial vision, he was able to manage till 1996 when he had his next cataract surgery. During that time, doctors said that he is having problem in his optic nerve and his vision would degrade. Later during 2003 again he had complete loss of vision after which he was given steroid treatment. With the help of the treatment he was having around 20% vision. But his vision was degrading day by day and this month (oct-2007) he is almost blind. Everywhere I read that there is no possibility of regeneration of optic nerve and this article has given me some hope. I sincerly wish that the research should succeed which would help so many people like us.
If you have any updated on the treatment and possibility of vision for people like him, please, please mail me at sofia_162k@yahoo.com.
I would be very grateful to anyone who helps me in this regard.
Thanks,
Sofia.
EYE REsearch
Dear Dr. Chen ,My name is Lisa, and I am speaking for my sister Kathy.after being diagnoised with ALL and undergoing radical chemotherapy,and recicieving a bone marrow transplant.While in her 3 mo .recovery in the hope house in tampa ,FL,she started losing her site,the specialist stated maybe she had a bac. or viral infection, or maybe her blood got to low,she also took a bad fall baackwards. Iwas her caregiver at the time and since this incident she only has,dim sight , has tunnel vision that is almost non existent.We need your desperate help,she has 4 daughters 2 of which are very young,and she is trying to raise them with this handicap,sense her illness her hunsband has deserted her and her children,and pays no support.Please bless this family. sincerely LISA
chemical injury by phosphoric acid
i am very interested in ur research...pls inform me of what i can do to help in anyway i can...and pls inform me of the progress.my sister currently has only light perception sustained by the chemical injury....pls.pls.email me:mkck8@yahoo.com
Optic Nerve
Hi, I am loosing my vision and suspected to have inheritance pattern of ?autosomal dominant ?mitochondrial.
If anyone has information on this would you please email me at harish.psp@gmail.com
Thanks
Harish
help
my 11 month old daughter has brain damage caused at birth which has left her blind. she is the light of my life. please let me know of any chance heroptic nerves can be fixed. i would do anything for the chance.
Transynaptic nerve degeneration
My daughter has just turned three, we found out she has Neonatal alloimmune thrombocytopenia. She had a stroke and as a result has a porenecphalic cyst in her left occiptal lobe. Over the last 6 months her optic nerves have gone from healthy to pale...
I'm waiting for specialist to say use this or do that.. I don't want my daughter to lose her sight. Count her in. nm_ribbon@hotmail.com.
Dr. Dong Feng Chen i would love to hear if there is anything i can do to help my daughter... At this stage her vision has not declined but its hard to really know.
thanks nikki
still hoping
My mother had her first brain tumor about 15 years ago. Both of her visions and hearing had gradually decreased over those years. The brain tumor damaged her nerves, which one I can't remember. Just last year she had her second brain tumor and now her visions are completely gone. She is totally blind and deaf. Her neurosurgeon and opthamologist said there were no cures for her. They are surprised that the brain tumors could result in her blindness. After reading your researches, I am very happy to learn that there might be hope to help someone like my mother to see again, even if it was a little bit. It is very hard to communicate with her and vice versa, but now and then I would hear her mumble if she could just be able to see a little bit, that would even be like a dream come true to her. I am very eager to find out if there are treatments that can be done for her. I want to help my mother to be able to see again. Please contact me Keo at ksaipa@yahoo.com.
sounds promising
i am a university student who is blind in my right eye due to nerve damage caused by domestic abuse as a child. any information u have about the subject, or participation in trials would be greatly welcomed. my email is tk56@kent.ac.uk
ONA Research
I am a 23 year old colege student from Washington State who has Optic Nerve Atrophy. I would like to find out if there is any research being conducted on hereditary forms of ONA. If anyone has information on this, please e-mail me at
noeone84@hotmail.com.
Yhanks
Noelle
I see one side of life
I had a fall 3 years ago and had bleeding on the brain, which damaged my optic nerve. My pereipheral vision to the left was damaged so I get to see 1 side of life. I'm based in the UK is there anyone in the UK carrying out this type of research? I can be contacted on michaelfoneill@hotmail.co.uk
this study on optic nerve repair sounds promising
I belive your niece will be able to see again very soon. If they are close to regenrating lost fingers and limbs, then optic nerves should be simpler.
Optic Nerve Regeneration
My 7 year old great-niece is legally blind. Her optic nerve was not fully developed at birth. Is their any hope for her to see again someday and be able to drive when she is sixteen?
Logan has one sister-6 years old and a brother-5 years old. They have been going through a very tragic time in their young lives. Their mother-24 years-(Brooke) old and baby sister (Kya)-7 months old were tragically murdered 10 weeks ago by Brooke's ex-boyfriend. My older sister, Brooke's mother and her husband are trying to get fully custody of the children since their father is a dead-beat dad. I am trying to get as much information on optic nerve regeneration for Logan. I can't bring her mom and baby sister back, but if someday God and science could give Logan her vision back..what a blessing that would be!
If anyone has information on this would you please email me at adshort@saintfrancis.com.
Thank You
optic nerve regeneration
hello every one... i'm a mother of 20 mnths old baby girl.... i'm soo glad i heard about this research as my cousin told me about it and i called one of the assistants in the research and she told me that they want to make sure first about if the treatment is safe because they want to know for sure if the regeneratin of optic nerve would help in restoring the sight.... my baby lost her vision when she was 9 months old she was seeing very well but she had increased brain fluid and they put a shunt which got blocked later and put a pressure on the optic nerve and caused the injury and atrophy..... i hope this study would help her and if there any participation we are welling to be with you ..........
Pray for a miracle
My son was lifted about 50 feet in the air by a canvas canopy and dropped to the ground, we had a 1% he would survive this terrible TBI, but almost 2 years later he is recovering wonderfully, the worst is he lost his vision totally. Please contact us if any new updates or treatments are available, we are willing to try anything.
He is 23 years old.
optic nerve
Hello, my name is Michelle and I was doing some periodic research and saw your inquiry. My husband is blind due to his optic nerve being severed. Did you get any reply to your question about human study?
I had emailed Dr. Chen, the author of the above study, some months back, and she told me she thinks they are about two years away from experimenting on primates, which is an FDA requirement. My husband lost his sight about 18 years ago, and at that time we were told blindness due to a severed optic nerve is permanent; they have made great strides!
Help pls
My aunt in her childhood fell down and lost her vision . Now she is 40 . Any possiblity to bring back her vision ?? expecting the suggestions and help ..
Optic Nerve Regeneration
I would be very interested in learning more about this - I had my left optic nerve cut due to the removal of a brain tumor which as a result has left me blind in that eye.
I would be more than happy to participate in any trials or research.
Please reply to morgan.a.horwood@gmail.com
Thank you!
Anterior Ischemic Neurotpathy
I also have limited lost in both eyes due to this condition. I would welcome any assistance.
Anterior Ischemic Optic Neuropathy
My husband has lost vision in both eyes due to AION. We are hoping and praying for a miracle. Anyone with any information or updates regarding new treatments, please write. Thank you. Julie, FROM CALIFORNIA
Anterior Ischemic Optic Neuropathy
My husband has lost vision in both eyes due to AION. We are hoping and praying for a miracle. Anyone with any information or updates regarding new treatments, please write. Thank you. Julie, FROM CALIFORNIA
Optic Nerve Regeneration
I'm sorry to hear about your friend. My little 13 year old brother was in a dirt bike accident and he too had swelling of the brain which caused damage to the optic nerve. He lost his sight in his right eye. I am curious to whether anyone wrote you back about humans being able to participate in this research. I would love for my little brother to see again with both of his eyes.
Amanda
Optic Nerve Cut Blocked or Streched
Firstly i would like to say that i am pleased with this research and was interested in whether it could help me as i have suffered in a car accident 4 years ago in which i lost my accident. in my opinon i bellive that before i was opeate on i did have sight but am not 100% sure matybe it was my imagination as previously doctors have told me. The doctors that i have spoke to have given me a variety of answers some saying it has been streched some saying that it has been damaged and some saying it has been cut. i would be very interested in this optic nerve testing so if you please get back to me by contacting me on my email address or mobile number which are mr_ahmed005@hotmail.co.uk and number is 07788681005
Thankyou.
optic nerve damage
Optic Nerve Regeneration
This research sounds wonderful. I have a friend who sustained injuries in a motorcycle accident about a year ago. One of his injuries resulted in swelling of the brain which caused damage to the optic nerve. As a result he lost his sight. I was wondering how someone in his situation could become qualified for participation in such research, if this is possible? I talked to him just last night and he informed me of this research and asked if I might inquire upon his behalf. If this type of participation would be possible please contact me at the above listed email address. Thank You!
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