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Vaccine for herpes in final trial phase

A nationwide trial is underway for a vaccine to prevent herpes infections. Approximately one out of four women in the United States has genital herpes. Symptoms are often subtle, and most people don't know they have herpes, but genital herpes is among the most common infectious diseases. Healthy women aged 18-30 may be eligible to participate in the trial. From the Mount Sinai School of Medicine :New vaccine for herpes in final trial phase

Mount Sinai School of Medicine is seeking healthy women volunteers 18-30 to participate in Multi-Center, national trial

Approximately ONE out of FOUR women in the United States has genital herpes. Symptoms are often subtle, and most people don't know they have herpes, but genital herpes is among the most common infectious diseases. This is why Mount Sinai School of Medicine has joined with the National Institute of Allergy and Infectious Diseases and GlaxoSmithKline Biologicals in the Herpevac Trial for Women. Healthy women aged 18-30 may be eligible to participate in the trial.
The herpes virus causes cold sores and genital herpes. Although thousands or millions of Americans have the disease, 90% are unaware of this infection. Even people who do not have visible symptoms can spread the disease. The disease burden is estimated at between $300 million to $1 billion per year in the US alone. There is no treatment that can eliminate the virus.

The Herpevac Trial for Women is investigating a promising vaccine to protect women against genital herpes. This vaccine does not contain live virus and cannot cause herpes infection. It has passed preliminary testing for safety and effectiveness and is now in its final phase of clinical trials.

For this study, Mount Sinai and the more than 20 other sites involved in the trail are seeking to enroll approximately 7,550 women. The Herpevac Trial for Women is open to healthy females between the ages of 18 and 30 who are negative for both HSV-1 and HSV-2.

Women who are interested in volunteering for the clinical trial will receive a very accurate blood test that looks for antibodies (the immune system's response) to both HSV-1 and HSV-2. Participants can obtain results of the test by calling the Herpevac Trial for Women Test Result Hotline two weeks after having the blood drawn. In addition to providing results, this Hotline has trained counselors to answer questions about the test and test results so that women who test positive for herpes can understand what this means to them.

Volunteers will be randomly assigned to receive either the candidate herpes vaccine or and an investigational hepatitis A vaccine. Participants will receive three doses of either vaccine within the first six months of the trial and will be followed for a total of 20 months through periodic clinic visits and contacts.

January 21, 2004

Comments

Another Multimillion Vac?

June 2, 2009 by Anonymous, 4 weeks 4 days ago
Comment id: 37002

Getting sick in this country is not only expensive but frustrating. Every system in the USA moves along with money, and we know labs and scientists work along with the system, "No pain not game". Does anybody has an idea how much money we'll pay for that? Would health insurance be able to pay for vaccine and for any recurrence tx? It is all about money in between. In fact, if this work for women, what fate is for men? Only women will be safe on this earth? (No man's land). Sorry guys, perhaps social security benefits will cover some palliative care! Meanwhile, lets practice safe sex and try to live not survive. Remember, we were born sick cause our parents were not healthy at all as they thought. God bless us all.

Hope on the Horizon

May 25, 2009 by Anonymous, 5 weeks 5 days ago
Comment id: 36835

I am a 29 year old female who has had this for 10yrs. I have had 2 long term relationships one being a marriage which ended and i have a healthy child who is now 6. I am hoping that this vaccine is not another hoax to get us excited. The good thing about this is although you have it, it wont be as hard to tell someone if there is something around to prevent them from getting it to. I also read somewhere that they are researching a way to help prevent us from passing it along and getting outbreaks. If all this is true and it is just a matter of years not decades or more than I am excited, and will actually look forward to being with someone.

you're not alone.

May 18, 2009 by Anonymous, 6 weeks 5 days ago
Comment id: 36714

I was diagnosed when I was 21 and I am now 23. It so hard to continualy be "punished" for someone lieing to me. I don't have a live in boyfriend. But I have been surprised friends have been able to be very supportive. Dating gets difficult at about week 3, but allot of the stigmatizims are starting to disappear. Hang in there. It could be a worse disease and allot of the shame comes from yourself not other people.

you can have children even as

May 14, 2009 by Anonymous, 7 weeks 2 days ago
Comment id: 36645

you can have children even as you have the herpes disease. In your last trimester of the pregnancy, they will give you medicine, so that you do not pass the disease on to the newborn. babies are born with their own immune system, not the mother's. You should research the disease more. I know a couple that has the disease and has a child. Don't let this disease affect your life because you are way young. I wish you the best...

ii was just diagnosed i am 30

May 13, 2009 by Anonymous, 7 weeks 3 days ago
Comment id: 36629

ii was just diagnosed i am 30 and was infected by my asymptomatic live in boyfriend we are both devastated im super depressed and have no desire in sex and his guilt is so tremendous he cant even look at me. I spoke with the biovex doctor and he said it will be at least 8 years before anything hits the market. they are having trouble with funding and wont be starting phase 1 clinical trials until next year. to say that we are devasted in an understatement.

Thanks

May 12, 2009 by Anonymous, 7 weeks 4 days ago
Comment id: 36596

Really nice work.. http://www.fsbnetwork.com

Keep Hope Alive

May 6, 2009 by Anonymous, 8 weeks 3 days ago
Comment id: 36525

Interesting site and claims.
The money back guarantee is nice, but I'm still skeptical.
Any info to credit or discredit these citric acid therapies would be nice.
Thanks (from all of us)

Clinical Trials

April 30, 2009 by Anonymous, 9 weeks 2 days ago
Comment id: 36448

Anyone who has herpes can help by volunteering for clinical trials in your area:

http://clinicaltrials.gov

Stop trying to cure; TREAT

April 28, 2009 by Anonymous, 9 weeks 4 days ago
Comment id: 36425

You cannot cure herpes. It's a virus. But you can prevent outbreaks by taking a daily lysine tablet. Also, keep your health up, eat right, exercise, and try not to stress. Anyone who tells you they can cure herpes is either lying or misinformed.

Help Me Get Rid of Herpes

April 28, 2009 by Anonymous, 9 weeks 4 days ago
Comment id: 36423

I just came from the a clinic in Indiana and I'm getting Ozone and peroixde treatment. I got the virus last year but thus far the virus affects me off and on. I'm really trying to get rid of it. What has been your experience with trying to get rid of this monster. I need a cool friend; hell if we all pull together just mabe we can kill it. My name is larry.

to anonymous

April 21, 2009 by Anonymous, 10 weeks 4 days ago
Comment id: 36301

don't let it destroy your life, there are forums where u can meet other people with it, in your area. YOu would be suprised how many people have this. My wife and i had to wonderful kids with herpes, the last she had an active outbreak. Make sure you tell ur doc and tell him u want a c section, to prevent any such possible spread.

This is not as bad as it seems, things could be much worse. ALOT of people have herpes 2, ALOT. I bet 10% of your friends have it and just don't mention it......by the time they are 40, 50% will have it. 1 in 5 active adults have it.

Go to the forums, meet people there. google herpes forums.

Hang in there kid, good luck and it's not the end of the world. If u have sex, make sure there are no active lesions and use protection.

There is a cure for herpes.

April 17, 2009 by Anonymous, 11 weeks 23 hours ago
Comment id: 36232

There is a cure for herpes. But they will not put it on the market until 90% of the popullation is infected. There's been a cure for 20 years! I'm 18. Why must me and everybody suffer. We only get one life I'm tired of being depressed my whole life. I want my life back. I want kids but I will not have kids if they have a chance of getting herpes when they are born. The reason why they put it on the market is cause of money they make millions if not billions a year for herpes treatments an medicine. The world is nothin but greedy as people trying to make a buck. I feel them. But dont make others suffer. I want to enjoy my life. But now I cant there won't be a minute that goes by that I won't think about me havin herpes. For all thoses that do have herpes I feel you pain. Try your best to life your life have fun an keep your immune system strong.

herpes vaccine

April 17, 2009 by Anonymous, 11 weeks 1 day ago
Comment id: 36228

The possible herpes vaccine under investigation is DL5 29 developed by David Knipe and his team of researchers at Harvard. Acambis, now part of Sanofi Pasteur, is the exclusive licensee for development of this vaccine trough the human trial phase. Pre-clinical testing has shown promising results in animal models of disease. With any luck, investigational new drug status will be granted this year and human trials can begin.

it is not so simple

April 13, 2009 by Anonymous, 11 weeks 4 days ago
Comment id: 36105

nobody whats to cure something that makes money!!! by another drugs.
sad but true!!!!!
so there is no cure for long time. but vaccine maybe comes??? becouse that is not cure.

Dr. Bryan Cullen please succeed!

April 4, 2009 by Anonymous, 13 weeks 10 hours ago
Comment id: 35832

I am also interested in a possible cure or vaccine. Any additional news?

Acambis - Sanofi Pasteur

March 31, 2009 by Anonymous, 13 weeks 4 days ago
Comment id: 35744

Sanofi-Pasteur just gobbled up Acambis for $549mn. Last year Acambis announced that it had a promising vaccine that is good in men & women & could also help folks already afflicted with recurrent HSV-2. This looks like the most promising breakthrough on the horizon and they are apparently supposed to be filing an "investigational drug" application sometime in 2009 which would make it more accessible to the public.

Harvard is somehow involved with this Acambis vaccine and they have a huge research endowment. The competition is fierce out there which is good for anyone with or at risk for HSV 1 or 2. American women are really affected by HSV-2 - about 30% and that just stinks. They estimate that a vaccine will generate the winner $2bn a year in revenue - that's a big prize. With the Valtrex patent expiring in June 2009 you're bound to see some breakthroughs.

The Virus

March 26, 2009 by Anonymous, 14 weeks 2 days ago
Comment id: 35645

I've read an article in Time Magazine about there being a possible cure on the horizon so to speak for HSV1 & 2. Here's the link to the article,

http://www.time.com/time/health/article/0,8599,1819739,00.html

My question is this, does anyone know if there are any 2009 updates on both the vaccine spoken about above & a possible cure stated in the article for HSV 1 & 2??

I think there will be a cure

March 2, 2009 by Anonymous, 17 weeks 5 days ago
Comment id: 34993

I feel every state is competing with each other to see who comes out the cure. Who cares? The people living with it will be very happy and appreciate the researchers who are working every day to eradicate this virus from the human body. I have faith in them. Good luck

a little more on the subject

February 24, 2009 by Anonymous, 18 weeks 4 days ago
Comment id: 34786

Okay from what I have learned everyone this vaccine works for women not men really has to to with the mucous lining or something....and it doesn't cure it yet only prevents it....Here are some links i have found http://www.niaid.nih.gov/dmid/stds/herpevac/studyover_faqs.htm
http://www.webmd.com/genital-herpes/news/20021120/new-herpes-vaccine-aff...

herpes

February 19, 2009 by Anonymous, 19 weeks 2 days ago
Comment id: 34698

Once you have a virus vaccines won't work, I think they are only preventative.

IM IN NO MATTER WHAT...

February 14, 2009 by Anonymous, 20 weeks 10 hours ago
Comment id: 34571

I JUST FOUND OUT I HAVE BOTH TYPES. IM ONLY 22 AND LOOKING FOR A WAY OUT.
I HAVE BEEN READING UP ON SO MANY THINGS ONLINE AND ITS FRUSTRATING THAT SOMETHING IS "ALMOST" OUT THERE BUT STILL, NOTHING HAS COME OUT.

I HAVE FOUND SOME SORT OF DETOX THAT CLAIMS TO REMOVE THIS VIRUS. TO READ MORE ABOUT IT GO TO: WWW.RESOLVEHERPES.COM

DOES ANY ONE HAVE ANY NEWS ON ANY TRIALS? I WILL BE UP FOR ANYTHING TO HELP NOT JUST MYSELF BUT OTHERS WITH THIS "THING".

herpevac only works on women who are not infected.

January 30, 2009 by Anonymous, 22 weeks 1 day ago
Comment id: 34132

Its a very limited vaccine. Women that are not infected can get it. It is estimated to have only a 50% protection rate. It is still questionable if it will ever hit the market.

is this a cure for infected hsv 1 & 2 or prevention against it

December 16, 2008 by Anonymous, 28 weeks 4 days ago
Comment id: 33392

The article does not really mention if it is for carriers of the disease.
Regards

Time frame?

December 11, 2008 by Anonymous, 29 weeks 2 days ago
Comment id: 33318

Is there a time frame on this vaccine? I have genital herpes is there anything about a cure?

Herpevac

October 19, 2008 by Anonymous, 36 weeks 6 days ago
Comment id: 32463

Unfortunately this vaccine is only for women

Anyone have any more

September 7, 2008 by Anonymous, 42 weeks 6 days ago
Comment id: 31849

Anyone have any more information on this vaccine? I have been diagnosed w/ HSV1 and would like my boyfriend to get this vaccine asap. Also, would the vaccine prevent cold sores from spreading to the genitals?

The Cure video > potential cures and vaccines against herpes

May 17, 2008 by Anonymous, 1 year 6 weeks ago
Comment id: 29892

Wanted to share a video I made about potential cures and vaccines against the herpes simplex virus.

http://www.youtube.com/watch?v=71FWd42iKYw

Hope you like it!

/Daniel

I hope this doesn't end like Tetrasil/Immusil

April 2, 2008 by Anonymous, 1 year 13 weeks ago
Comment id: 28473

Tetrasil was looking so hopeful that I was The #1 spokesman for the company. I even went to a few health food stores and got them to order it.
I even told people on the street about it.
Then one day as fast as it appeared it faded away.
It was supposed to be the ultimate viral/pathogen eliminator. Nanotechnology in a bottle able to penetrate spinal tissue and destroy AIDS, Herpes etc.
Up to this day I don't know what happened.
My whole future went poof! Now I'm back to waiting and hoping for something else to appear. I figured the combination of DMSO and tetrasil would guarantee the elimination of any HSV. Oh well.........back to the drawing board.

stop counting the patients

March 11, 2008 by Anonymous, 1 year 16 weeks ago
Comment id: 28055

I don't think this vaccine would work effectively,because what Pharmaceutical companies put first is how much money will they get? if they find vaccine or treatment.

Could be a shame

February 22, 2008 by Anonymous, 1 year 19 weeks ago
Comment id: 27712

Do you think the makers of Zovirax want a vaccine? That's why it has taken this long...the Pharm's will figure out a way to make this "herpvac" disappear like all the rest

can you give us an update on the vaccine?

February 1, 2008 by Anonymous, 1 year 22 weeks ago
Comment id: 27297

can you give us an update on the vaccine?

Hepes treatment

December 8, 2007 by Anonymous, 1 year 29 weeks ago
Comment id: 26368

Hello,
I was diagnosed with the HSV2 last year, my friend who is a accupuntruist told me I should keep my immune system strong. He suggested I should take Lysin daily and also collostrum. I take both daily and it seems it help me with the outbreaks, I do not get them as often.

Good luck, hope there will be a cure soon.

Question

November 13, 2007 by Anonymous, 1 year 33 weeks ago
Comment id: 25955

Does herpes affect grammatical capabilities or are the above the exception?

when going to be ready the

August 13, 2007 by luis (not verified), 1 year 46 weeks ago
Comment id: 24511

when going to be ready the vaccine for herpes

TREAMENT

July 19, 2007 by JAMELL (not verified), 1 year 50 weeks ago
Comment id: 24291

I AM YOUNG WOMAN AND I HAVE HERPES AND I WILL LIKE BE VOLUNTEER FOR ANY VACCINNE FOR HERPES FOR ANY trial I HAVE THE SUPPORT OF MY FATHER PLEASE I WAIT FOR ANY ANWSER I WILL BE HERE WAITING BYE AND THANK YOU

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