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GUMC discovery highlights new direction for drug discovery

Washington, DC -- In a discovery that rebuffs conventional scientific thinking, researchers at Georgetown University Medical Center (GUMC) have discovered a novel way to block the activity of the fusion protein responsible for Ewing's sarcoma, a rare cancer found in children and young adults.

Blood stem cell growth factor reverses memory decline in mice

Tampa, FL (July 1, 2009) -- A human growth factor that stimulates blood stem cells to proliferate in the bone marrow reverses memory impairment in mice genetically altered to develop Alzheimer's disease, researchers at the University of South Florida and James A. Haley Hospital found.

Cancer researchers link DICER1 gene mutation to rare childhood cancer

WASHINGTON, DC -- Research published today in Science Express from the journal Science demonstrates the first definitive link between mutations in the gene DICER1 and cancer.

U-M study finds voice box can be preserved, even with the largest cancers

ANN ARBOR, Mich. -- Some patients with large tumors on their larynx can preserve their speech by opting for chemotherapy and radiation over surgery to remove the voice box.

A new study from the University of Michigan Comprehensive Cancer Center found that a single round of chemotherapy could identify those patients most likely to benefit from this approach.

Anti-inflammatory drugs may defeat a treatment-resistant type of cancer

Effective drugs for treating a chemotherapy-resistant form of lymphoma might already be on the market according to a study that has pieced together a chemical pathway involved in the disease.

Study pinpoints novel cancer gene and biomarker

BOSTON--Dana-Farber Cancer Institute scientists' discovery of a cancer-causing gene -- the first in its family to be linked to cancer -- demonstrates how the panoramic view of genomics and the close-up perspective of molecular biology are needed to determine which genes are involved in cancer and which are mere bystanders.

Targeting tumor behavior may lead to new liver cancer drugs

COLUMBUS, Ohio -- Ohio State University cancer researchers have used computational and genomic methods to identify possible anti-cancer agents that may block a particular kind of tumor behavior. The agents target multiple genes associated with that behavior at one time.

St. Gallen consensus 2009: A radically different approach to treating early breast cancer

A radically different approach to choosing the best treatment options for early breast cancer has been proposed by an international panel of experts in a report from the 11th St Gallen conference.

Key found to how tumor cells invade the brain in childhood cancer

New York, June 17, 2009 -- Despite great strides in treating childhood leukemia, a form of the disease called T-cell acute lymphoblastic leukemia (T-ALL) poses special challenges because of the high risk of leukemic cells invading the brain and spinal cord of children who relapse.

UCF researcher's nanoparticles could someday lead to end of chemotherapy

Nanoparticles specially engineered by University of Central Florida Assistant Professor J. Manuel Perez and his colleagues could someday target and destroy tumors, sparing patients from toxic, whole-body chemotherapies.

Potential for non-invasive brain tumor treatment

DURHAM, N.C. -- Duke University engineers have taken a first step toward a minimally invasive treatment of brain tumors by combining chemotherapy with heat administered from the end of a catheter.

UCLA cancer researchers develop model that may help identify cancer stem cells

Researchers at UCLA's Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers.

Test detects molecular marker of aging in humans

CHAPEL HILL, N.C. -- In 2004, researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center announced a crucial discovery in the understanding of cellular aging. They found that as cells and tissues age, the expression of a key protein, called p16INK4a, dramatically increases in most mammalian organs.

US counties with more African-American patients may have fewer colorectal cancer specialists

Each percentage point increase in the African American population in a county appears to be associated with a decrease in the number of specialists within that county who diagnose and treat colorectal cancer, according to a report in the June issue of Archives of Surgery, one of the JAMA/Archives journals.

Topical application of chemotherapy drug may improve appearance of aging skin

Topical application of the chemotherapy medication fluorouracil appears to reduce potentially precancerous skin patches and improve the appearance of sun-damaged skin, according to a report in the June issue of Archives of Dermatology, one of the JAMA/Archives journals.



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