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Nanoparticles cross blood-brain barrier to enable 'brain tumor painting'

Brain cancer is among the deadliest of cancers. It's also one of the hardest to treat. Imaging results are often imprecise because brain cancers are extremely invasive. Surgeons must saw through the skull and safely remove as much of the tumor as they can.

Multimodality treatments effective in halting lung cancer progression

SAN FRANCISCO, August 3, 2009 -- The world?s top lung cancer specialists, medical professionals and researchers are convening this week in San Francisco, CA for the 13th World Conference on Lung Cancer (WCLC), organized by the International Association for the Study of Lung Cancer (IASLC).

PET can help guide treatment decisions for a common pediatric cancer

RESTON, Va. -- A new study published in the August issue of The Journal of Nuclear Medicine shows that positron emission tomography (PET) is an important tool for depicting the extent of neuroblastoma in some patients, particularly for those in the early stages of the disease.

Fox Chase finds all-biologic regimen efficacious and well-tolerated in elderly lung cancer patients

SAN FRANCISCO (August 1, 2009) -- Previously untreated non-small cell lung cancer (NSCLC) patients over the age of 70 respond well to a combination of bevacizumab and erlotinib, Fox Chase Cancer Center researchers reported today at the annual meeting of the International Association for the Study of Lung Cancer.

Advanced targeted therapies effective as first-line treatment for lung cancer

SAN FRANCISCO, August 1, 2009 -- The world's top lung cancer specialists, medical professionals and researchers are convening this week in San Francisco, CA for the 13th World Conference on Lung Cancer (WCLC), organized by the International Association for the Study of Lung Cancer (IASLC).

MIT team targets ovarian cancer with nanoparticles

CAMBRIDGE, Mass. -- Tiny particles carrying a killer gene can effectively suppress ovarian tumor growth in mice, according to a team of researchers from MIT and the Lankenau Institute.

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

PHILADELPHIA -- Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research, a journal of the American Association for Cancer Research.

A crystal ball for brain cancer?

UCLA researchers have uncovered a new way to scan brain tumors and predict which ones will be shrunk by the drug Avastin -- before the patient ever starts treatment. By linking high water movement in tumors to positive drug response, the UCLA team predicted with 70 percent accuracy which patients' tumors were the least likely to grow six months after therapy.

EphA2-targeted therapy delivers chemo directly to ovarian cancer cells

HOUSTON - With a novel therapeutic delivery system, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center has successfully targeted a protein that is over-expressed in ovarian cancer cells.

Low prevalence of HPV infection may be tied to poor prognosis for blacks with head and neck cancer

Researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer have found that head and neck cancer patients who test positive for the human papillomavirus (HPV) have much better survival rates than patients who don't have the virus, according to a new study in the journal Cancer Prevention Research. The researchers also discovered that blacks in the study had a very low

New drug for children with high-risk leukemia

Each year, approximately 4,500 children in America are diagnosed with leukemia, according to the Leukemia and Lymphoma Society. A potentially deadly cancer of the blood, it is the most common cancer in children.

'Corrective genes' closer thanks to enzyme modification

Scientists from the Université de Montréal and McGill University have re-engineered a human enzyme, a protein that accelerates chemical reactions within the human body, to become highly resistant to harmful agents such as chemotherapy, according to a new study published in The Journal of Biological Chemistry.

Genetic testing may be valuable in treating colorectal cancer

NEW YORK (July 27, 2009) -- For the 29,000 patients in the United States with metastatic colorectal cancer, chemotherapy with irinotecan is a standard treatment that has been shown to improve survival.

Surgery remans an option for advanced lung cancer

MAYWOOD, Il. -- In recent years, oncologists have debated whether patients with a certain type of advanced lung cancer would benefit from surgery.

Stripping leukemia-initiating cells of their 'invisibility cloak'

Two new studies reveal a way to increase the body's appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate.



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