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Important defense against stomach ulcer bacterium identified

A special protein in the lining of the stomach has been shown to be an important part of the body's defense against the stomach ulcer bacterium Helicobacter pylori in a new study from the Sahlgrenska Academy at the University of Gothenburg. The discovery may explain why the bacterium makes some people more ill than others.

Duke/Singapore scientists find new way to classify gastric cancers

DURHAM, N.C., -- An international team of scientists has discovered a new way to classify stomach cancers, and researchers say it may be an important step toward designing more effective treatments and improving long-term survival.

Stomach (gastric) cancer is particularly prevalent in Asia and represents the second leading cause of cancer deaths worldwide.

Cutting sodium consumption: A major public health priority

Reducing sodium intake is a major public health priority that must be acted upon by governments and nongovernmental organizations to improve population health, states an article http://www.cmaj.ca/press/cmaj090361.pdf in CMAJ (Canadian Medical Association Journal)

Uncovering the secrets of ulcer-causing bacteria

A team of researchers from Boston University, Harvard Medical School and Massachusetts Institute of Technology recently made a discovery that changes a long held paradigm about how bacteria move through soft gels.

What are factors associated with use of gastric cancer screening services in Korea?

The mortality of gastric cancer is decreasing despite the increasing incidence in Korea. This can be explained by surgical technique development and early detection by endoscopic screening or upper gastrointestinal study.

Columbia team finds that gastrin plays significant role in helicobacter-induced stomach cancer

A group led by Columbia University Medical Center's Timothy Wang, M.D., has studied the role of Helicobacter infection in the development of stomach cancer and found that the hormone gastrin, which stimulates secretion of gastric acid, plays a key role in the development of Helicobacter-induced stomach cancer, and may have distinct effects on carcinogenesis in different parts of the stomach.

LSUHSC research finds single gene controls growth of some cancers

New Orleans, LA -- Research led by Ashok Aiyar, PhD, Associate Professor of Microbiology at LSU Health Sciences Center New Orleans, showing that a single gene can control growth in cancers related to the Epstein-Barr virus and that existing therapeutics can inactivate it, will be published in the June 12, 2009 online issue of PLoS Pathogens.

Glutamine supplements show promise in treating stomach ulcers

BOSTON - Nearly 20 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Since then, antibiotics have become the primary therapy used to combat the H. pylori infection, which affects approximately six percent of the world population and is also a primary cause of stomach cancer.

Novel therapy may prove effective in treatment of 30 percent of cancers

A ground-breaking Canada-wide clinical trial led by Dr. Katherine Borden, at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal, has shown that a common anti-viral drug, ribavirin, can be beneficial in the treatment of cancer patients.

New minimally invasive surgery option for patients with stomach cancer

A novel, minimally invasive surgical approach to treat stomach cancer has been shown to have advantages that may make it a preferable treatment for some patients.

Broccoli sprouts may prevent stomach cancer by defeating Helicobacter pylori

PHILADELPHIA - Three-day-old broccoli sprouts, a widely available human food, suppressed Helicobacter pylori (H. pylori) infections, according to a report in Cancer Prevention Research, a journal of the American Association for Cancer Research. H. pylori infections are one of the most common bacterial infections worldwide and are a major cause of stomach cancer.

Body's own anti-bacterial fights cancer in gut

An international team has discovered that a human glycoprotein inhibits Helicobacter pylori (''H. pylori''), the bacterium that causes stomach ulcers and is linked with 90% of stomach cancers. The results present a new way of looking at treating chronic inflammation associated with stomach ulcers, and introduces the possibility of preventing stomach cancer associated with H. pylori.

Vitamin C may protect against ulcer-causing bacteria

A study led by researchers at the San Francisco VA Medical Center (SFVAMC) has found that the lower the level of vitamin C in the blood the more likely a person will become infected by Helicobacter pylori, the bacteria that can cause peptic ulcers and stomach cancer. "This is the largest study to look at the relationship between vitamin C levels and infection by H. pylori," said Joel A. Simon, MD, MPH, SFVAMC staff physician and UCSF associate professor of medicine and epidemiology and biostatistics.

New chemotherapy combination lengthens survival in late stage stomach cancer

Adding docetaxel to the most commonly used combination chemotherapy improved tumor regression rate, delayed tumor growth and prolonged survival for patients with advanced stomach cancer, according to interim results of a Phase III international clinical trial presented at the annual meeting of the American Society of Clinical Oncology.

Pylori Paradox: Microbe Harms Stomach But Protects Esophagus

When it comes to the microbes that inhabit the gastrointestinal tract, one person's poison may be another's cure. Heliobacter pylori, the bacterium that causes gastric ulcers and stomach cancer in some people, may actually protect against cancer of the esophagus. A new study by researchers at the Oregon Health and Science University in Portland is shedding some light on this baffling paradox.



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