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Novel anti-cancer drug yields positive response in people with advanced skin and brain cancer

The Hedgehog signaling pathway is involved in a preliminary study and case report describing positive responses to an experimental anticancer drug in a majority of people with advanced or metastatic basal cell skin cancers. One patient with the most common type of pediatric brain cancer, medulloblastoma, also showed tumor shrinkage.

NIH study reveals new genetic culprit in deadly skin cancer

Drawing on the power of DNA sequencing, National Institutes of Health researchers have identified a new group of genetic mutations involved in the deadliest form of skin cancer, melanoma.

Some brain tumors may be mediated by tiny filament on cells

UCSF scientists have discovered that a tiny filament extending from cells, until recently regarded as a remnant of evolution, may play a role in the most common malignant brain tumor in children.

Some skin cancer may be mediated by primary cilia activity

Tiny, solitary spikes that stick out of nearly every cell in the body play a central role in a type of skin cancer, new research has found. The discovery in mice shows that the microscopic structures known as primary cilia can either suppress or promote this skin cancer, depending on the mutation triggering the disease.

Dermatologist skin examinations detect more, thinner skin cancers than patients identify themselves

Most melanomas detected in a general-practice dermatology clinic were found by dermatologists during full-body skin examinations of patients who had come to the clinic for different complaints, according to a report in the August issue of Archives of Dermatology, one of the JAMA/Archives journals.

Sensitizing tumor response to cancer therapy

Two forms of skin and brain cancer respond very poorly to chemotherapy and radiation: melanoma and glioblastoma multiforme brain cancer.

Viral mimic induces melanoma cells to digest themselves

Recent research has uncovered an unexpected vulnerability in deadly melanoma cells that, when exploited, can cause the cancer cells to turn against themselves.

Study links virus to some cases of common skin cancer

COLUMBUS, Ohio -- A virus discovered last year in a rare form of skin cancer has also been found in people with the second most common form of skin cancer among Americans, according to researchers at the Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.

The researchers examined tissue samples from 58 people with squamous cell carcinom

Tips from the journals of the American Society for Microbiology

"Single-Shot" Vaccines May Protect Against H5N1 Influenza Virus

Australian researchers identify genes that cause melanoma

Scientists from the Queensland Institute of Medical Research (QIMR) have found two new genes that together double a person's risk of developing melanoma.

Study pinpoints novel cancer gene and biomarker

BOSTON--Dana-Farber Cancer Institute scientists' discovery of a cancer-causing gene -- the first in its family to be linked to cancer -- demonstrates how the panoramic view of genomics and the close-up perspective of molecular biology are needed to determine which genes are involved in cancer and which are mere bystanders.

Topical application of chemotherapy drug may improve appearance of aging skin

Topical application of the chemotherapy medication fluorouracil appears to reduce potentially precancerous skin patches and improve the appearance of sun-damaged skin, according to a report in the June issue of Archives of Dermatology, one of the JAMA/Archives journals.

New skin cancer patch: Possible alternative to surgery

TORONTO -- A new study shows that a radioactive skin patch can safely and successfully treat basal cell carcinoma, one of the most common types of skin cancers, according to researchers at the SNM's 56th Annual Meeting.

Wistar Institute team finds key target of aging regulator

Researchers at The Wistar Institute have defined a key target of an evolutionarily conserved protein that regulates the process of aging. The study, published June 11 in Nature, provides fundamental knowledge about key mechanisms of aging that could point toward new anti-aging strategies and cancer therapies.

Research Team Finds Key Target of Aging Regulator

Researchers at The Wistar Institute have defined a key target of an evolutionarily conserved protein that regulates the process of aging. The study, published June 11 in Nature, provides fundamental knowledge about key mechanisms of aging that could point toward new anti-aging strategies and cancer therapies.



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