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Reduced skin infections in Northern Australian Aboriginal children

A community-based program aimed at reducing the burden of skin disease across remote communities in Australia's Northern Territory has been successful according to a study published November 24 in the open-access journal PLoS Neglected Tropical Diseases.

Tips from the Journals of the American Society for Microbiology

Bacterially Produced Antifungal on Skin of Amphibians May Protect Against Lethal Fungus

Last-resort lower-body amputation effective in extreme cases of bone infection, 25-year review shows

DALLAS -- Nov. 17, 2009 -- A landmark, 25-year review of cases in which surgeons had to remove the lower portion of the body from the waist down for severe pelvic bone infections shows the therapy can add years and quality of life to survivors, say researchers at UT Southwestern Medical Center.

A second skin

Despite advances in treatment regimens and the best efforts of nurses and doctors, about 70% of all people with severe burns die from related infections. But a revolutionary new wound dressing developed at Tel Aviv University could cut that number dramatically.

Inappropriate sepsis therapy leads to fivefold reduction in survival

Patients experiencing septic shock who receive inappropriate therapy may have a fivefold reduction in survival, shows a new study.

Canadian scientists link fat hormone to death from potentially deadly blood infection

A new Canadian study has found that lower-than-normal levels of a naturally-occurring fat hormone may increase the risk of death from sepsis -- an overwhelming infection of the blood which claims thousands of lives each year.

Review: Pneumococcal conjugate vaccines effective at preventing child deaths

Washington, DC -- A study published in The Cochrane Review this month concludes that pneumococcal conjugate vaccines (PCV), already known to prevent invasive pneumococcal disease (IPD) and x-ray defined pneumonia, was also effective against child deaths.

Treatment of severe burn injuries

Almost three quarters of patients with extensive burns die of the consequences of a severe infection. In the current edition of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2009; 106[38]: 607-13), Timo A. Spanholtz of the Cologne-Merheim Burn Center and his coauthors discuss the acute therapy and follow-up care of burn disease.

Black patients have lower rate of survival after in-hospital cardiac arrest

Compared with white patients, black patients who have an in-hospital cardiac arrest are significantly less likely to survive to hospital discharge, having lower rates of successful resuscitation and postresuscitation survival, although much of this survival difference was associated with the hospital in which black patients received care, according to a study in the September 16 issue of JAM

Key feature of immune system survived in humans, other primates for 60 million years

CORVALLIS, Ore. -- A new study has concluded that one key part of the immune system, the ability of vitamin D to regulate anti-bactericidal proteins, is so important that is has been conserved through almost 60 million years of evolution and is shared only by primates, including humans -- but no other known animal species.

Discovery may lead to powerful new therapy for asthma

GALVESTON, Texas -- University of Texas Medical Branch at Galveston researchers have found that a single enzyme is apparently critical to most allergen-provoked asthma attacks -- and that activity of the enzyme, known as aldose reductase, can be significantly reduced by compounds that have already undergone clinical trials as treatments for complications of diabetes.

Scientists uncork a potential secret of red wine's health benefits

Scientists from Scotland and Singapore have unraveled a mystery that has perplexed scientists since red wine was first discovered to have health benefits: how does resveratrol control inflammation?

Leading pathogen in newborns can suppress immune cell function

Group B Streptococcus (GBS), a bacterial pathogen that causes sepsis and meningitis in newborn infants, is able to shut down immune cell function in order to promote its own survival, according to researchers at the University of California, San Diego School of Medicine and the Skaggs School of Pharmacy and Pharmaceutical Sciences.

New findings encourage more vigilant monitoring of seizure activity among intensive care patients

NEW YORK (June 17, 2009) -- Two new studies published by neurologists at Columbia University Medical Center and NewYork-Presbyterian Hospital demonstrate a need for more vigilant monitoring for seizure activity among intensive care patients who may be experiencing subtle seizures that are typically unrecognized.

Vanderbilt researchers pioneer an advanced sepsis detection and management system

When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread.



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