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Researchers begin to decipher metabolism of sexual assault drug

November 20, 2009

It's a naturally occurring brain chemical with an unwieldy name: 4-hydroxybutyrate (4-HB). Taken by mouth, it can be abused or used as a date-rape drug.

Greater certainty in monitoring 3 therapeutic medications is facilitated by new CRMs

November 18, 2009

Rockville, Md., November 18, 2009 -- To help bring greater certainty to the measurement of medication levels in a patient's bloodstream for three drugs with narrow therapeutic ranges, the U.S. Pharmacopeial Convention (USP) is releasing new certified reference materials (CRMs).

Research reveals lipids' unexpected role in triggering death of brain cells

November 12, 2009

The lipid that accumulates in brain cells of individuals with an inherited enzyme disorder also drives the cell death that is a hallmark of the disease, according to new research led by St.

Shire presents study findings on its ADHD treatments at psychiatric meeting Oct 29-30

October 29, 2009

HONOLULU -- October 29, 2009 -- Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced today that it will present key scientific data on its Attention-Defi

Treatment for epilepsy is a possible culprit for development of schizophrenia

October 20, 2009

CHICAGO -- Researchers say antiepilectic drug treatments administered when the brain is developing appear to trigger schizophrenia-like behavior in animal models.

Rare procedure documents how the human brain computes language

October 15, 2009

A study by researchers at the University of California, San Diego School of Medicine reports a significant breakthrough in explaining gaps in scientists' understanding of human brain function. The study -- which provides a picture of language processing in the brain with unprecedented clarity -- will be published in the October 16 issue of the journal Science.

Study may explain how a well-known epilepsy and pain drug works

October 13, 2009

DURHAM, N.C. -- A Duke University Medical Center researcher who spent years looking for the signals that prompt the brain to form new connections between neurons has found one that may explain precisely how a well-known drug for epilepsy and pain actually works.

The finding may also point to new therapies for brain injury and neuropathic pain.

Study pinpoints key mechanism in brain development, raising question about use of antiseizure drug

October 8, 2009

STANFORD, Calif. -- Researchers at the Stanford University School of Medicine have identified a key molecular player in guiding the formation of synapses -- the all-important connections between nerve cells -- in the brain.

Research ensures 50 million vaccinated against deadly brain infection

October 6, 2009

Research at the University of Liverpool has supported the vaccination of more than 50 million people against a zoonotic brain infection that affects thousands of children across Asia every year.

Gene mutation causes severe epilepsy, febrile seizures in thousands of infants worldwide

September 16, 2009

SALT LAKE CITY -- University of Utah medical researchers have identified a gene with mutations that cause febrile seizures and contribute to a severe form of epilepsy known as Dravet syndrome in some of the most vulnerable patients -- infants 6 months and younger.

High-res view of zinc transport protein

September 13, 2009

UPTON, NY -- How much difference can a tenth of a nanometer make? When it comes to figuring out how proteins work, an improvement in resolution of that miniscule amount can mean the difference between seeing where atoms are and understanding how they interact.

Virus responsible for deadly brain disease found in MS patients treated with natalizumab

September 9, 2009

BOSTON -- The virus responsible for PML (progressive multifocal leukoencephalopathy), a rare brain disease that typically affects AIDS patients and other individuals with compromised immune systems, has been found to be reactivated in multiple-sclerosis patients being treated with natalizumab (Tysabri).

MassGeneral Hospital for Children study explains some mysteries of neonatal seizures

September 9, 2009

A study led by MassGeneral Hospital for Children (MGHfC) investigators is providing new insight into the mechanism of neonatal seizures, which have features very different from seizures in older children and adults. In their report in the Sept.

Researchers restore missing protein in rare genetic brain disorder

September 6, 2009

UCSF researchers have successfully used protease inhibitors to restore to normal levels a key protein involved in early brain development. Reduced levels of that protein have been shown to cause the rare brain disorder lissencephaly, which is characterized by brain malformations, seizures, severe mental retardation and very early death in human infants.

Transplanted human stem cells prolong survival in mouse model of rare brain disease

September 3, 2009

A new study finds substantial improvement in a mouse model of a rare, hereditary neurodegenerative disease after transplantation of normal human neural stem cells.



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