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Pregnancy hormone changes linked to restless legs syndrome

A new study finds the elevation in estradiol levels that occurs during pregnancy is more pronounced in pregnant women with restless legs syndrome (RLS) than in controls.

Mixed signals to blame for restless legs syndrome

Iron-deficient cells in the brain are mixing up central nervous system signals to the legs and arms causing the irresistible urges to move and creepy-crawly sensations that characterize restless legs syndrome, a new study reports. ''Our previous studies established a physical cause for RLS showing certain cells in the brain were iron deficient... We have now found a sequence of events that may connect that cellular iron deficiency to the uncontrollable movements of the disorder.''

Crossover Drug Effective For Restless Legs Syndrome

An anticonvulsant drug typically used to control seizures and neuropathic pain may reduce symptoms among those who suffer from restless legs syndrome (RLS), a movement disorder that affects up to 10 percent of the population. RLS is characterized by an urge to move the legs, generally accompanied by unpleasant sensations; an increase of symptoms during rest and a partial, temporary relief of symptoms through activity; and worsening of symptoms in the evening or at night.



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