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Characteristic pathological findings in reflux esophagitis

Recently, the number of patients with GERD has increased in Japan. However, there have been few reports about the pathological findings in the esophageal squamous epithelium, and there are differing opinions among pathologists about the findings considered characteristic of chronic reflux esophagitis.　

Chronic diarrhea unresponsive to conventional medication: Are you taking lansoprazole?

Lansoprazole is a proton pump inhibitor which powerfully suppresses gastric acid production and is widely prescribed for chronic use in gastroesophageal reflux disease. Lansoprazole uncommonly causes chronic watery diarrhea unresponsive to conventional medication as a symptom of collagenous colitis. This association has recently been reported and is not widely known.

Is esomeprazole the best choice for reflux esophagitis patients?

In patients with gastroesophageal reflux disease (GERD), esomeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors( PPIs ). However it has not hitherto been fully determined whether differences in the onset of antisecreatary activity may affect the speed of symptom relief with different PPI.

Alcohol types and socioeconomic status are associated with Barrett's esophagus risk

Bethesda, MD (March 1, 2009) - Although the relationship between alcohol and esophageal squamous cell carcinoma is well established, studies investigating the association between alcohol intake and reflux esophagitis (RE), Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) have reported inconsistent findings.



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