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Multiple health concerns surface as winter, vitamin D deficiences arrive

CORVALLIS, Ore. -- A string of recent discoveries about the multiple health benefits of vitamin D has renewed interest in this multi-purpose nutrient, increased awareness of the huge numbers of people who are deficient in it, spurred research and even led to an appreciation of it as "nature's antibiotic."

Scientists discover cells that control inflammation in chronic disease

A new type of immune cell that can be out of control in certain chronic inflammatory diseases, worsening the symptoms of conditions like psoriasis and asthma, is described for the first time this week in the Journal of Clinical Investigation.

In shaping our immune systems, some 'friendly' bacteria may play inordinate role

Out of the trillions of "friendly" bacteria - representing hundreds of species -that make our intestines their home, new evidence in mice suggests that it may be a very select few that shape our immune responses.

Unusual bacteria help balance the immune system in mice

Medical researchers have long suspected that obscure bacteria living within the intestinal tract may help keep the human immune system in balance. An international collaboration co-led by scientists at NYU Langone Medical Center has now identified a bizarre-looking microbial species that can single-handedly spur the production of specialized immune cells in mice.

Anticancer compound found in American mayapple

VERONA, MS -- A common weed called American mayapple may soon offer an alternative to an Asian cousin that's been harvested almost to extinction because of its anti-cancer properties. The near-extinct Asian plant, Podophyllyum emodi, produces podophyllotoxin, a compound used in manufacturing etoposide, the active ingredient in a drug used for treating lung and testicular cancer.

Counting duplicated genome segments now possible

A newly designed computational method has proven its usefulness in counting copies of duplicated genome sequences and in doing initial assessments of their contents, according to a study to be published Aug. 30 in Nature Genetics. The number of copies of particular DNA segments can differ from one person to the next.

Gene variation is 'major genetic determinant of psoriasis'

(SALT LAKE CITY) -- A specific genetic region that has been increasingly identified as the strongest genetic link to psoriasis has an even more significant role in the chronic skin disease than has been suspected, University of Utah medical researchers show in a new study.

Skin-disease patients show brain immunity to faces of disgust

People with psoriasis -- an often distressing dermatological condition that causes lesions and red scaly patches on the skin -- are less likely to react to looks of disgust by others than people without the condition, new research has found.

Resolvyx announces positive data -- Phase 2 trial of resolvin RX-10045 for dry eye syndrome

BEDFORD, MA ?August, 24, 2009 -- Resolvyx Pharmaceuticals, Inc., the leading resolvin therapeutics company, today announced positive data from a Phase 2 clinical study evaluating RX-10045, a resolvin administered as a topical eye drop for the treatment of patients with chronic dry eye syndrome.

Post-transplant combo can replace toxic immune-suppressing drugs in monkeys

Transplant patients rely on drugs to prevent graft rejection, but at the cost of serious side effects. The class of immunosuppressive drugs known as calcineurin inhibitors (examples are cyclosporine and tacrolimus) can damage patients' kidneys and lead to high blood pressure, among other problems.

Psoriasis associated with cardiovascular disease and increased mortality

The skin disease psoriasis is associated with atherosclerosis (a buildup of plaque in the arteries) characterized by an increased prevalence of ischemic heart disease, cerebrovascular disease, peripheral artery disease and an increased risk of death, according to a report in the June issue of Archives of Dermatology, one of the JAMA/Archives journals.

A new lead for autoimmune disease

A drug derived from the hydrangea root, used for centuries in traditional Chinese medicine, shows promise in treating autoimmune disorders, report researchers from the Program in Cellular and Molecular Medicine and the Immune Disease Institute at Children's Hospital Boston (PCMM/IDI), along with the Harvard School of Dental Medicine.

Scientists discover new genetic immune disorder in children

Your immune system plays an important function in your health -- it protects you against viruses, bacteria, and other toxins that can cause disease. In autoinflammatory diseases, however, the immune system goes awry, causing unprovoked and dangerous inflammation.

Recent developments at Burnham Institute for Medical Research, May 2009

Human monoclonal antibodies effective against bird and seasonal flu viruses

Not just a long-distance relationship: Immune cells in skin fight off infection better than the rest

Scientists at the University of Melbourne have discovered the local action of immune cells in the skin, which could improve treatment of viral skin infections.

This work identifies previously unrecognised first-line defence mechanisms that are particularly important in barrier locations such as the skin and the gut, often used as portals of entry by viruses and bacteria.



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