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African American lung cancer patients may have different response to new cancer-fighting drugs

Clinical research out of University Hospitals Case Medical Center has found that African Americans with a common form of lung cancer have a lower frequency of drug-sensitizing genetic mutations, which may impact response to new cancer-fighting drugs.

Lung cancer risk increases with expression of specific genes

AURORA, COLO -- A recent study published in the October 2009 issue of the Journal of Thoracic Oncology determined that variations of specific genetic markers identified in previous research, or SNPs, may indicate a greater lung cancer risk in African Americans than in whites.

Narrow-band imaging increases specificity of early lung cancer detection

AURORA, COLO -- Research published in the September 2009 issue of the Journal of Thoracic Oncology has found that narrow-band imaging bronchoscopy increases the specificity of bronchoscopic early lung cancer detection and can serve as an alternative detection device.

Patients' pretreatment quality of life can predict overall lung cancer survival

AURORA, COLO -- Research published in the September 2009 issue of the Journal of Thoracic Oncology has found that an individual's quality of life prior to treatment can help predict the overall survival of patients with advanced stage non-small cell lung cancer (NSCLC).

Tumor size and level of visceral pleura invasion can impact survival of NSCLC patients

AURORA, Co -- A study published in the August 2009 edition of the Journal of Thoracic Oncology found that non-small cell lung cancer (NSCLC) patients could be more accurately staged at diagnosis by taking into account the level of visceral pleura invasion (VPI). VPI is the extension of a tumor beyond the elastic layer of the visceral pleura.

Multimodality treatments effective in halting lung cancer progression

SAN FRANCISCO, August 3, 2009 -- The world?s top lung cancer specialists, medical professionals and researchers are convening this week in San Francisco, CA for the 13th World Conference on Lung Cancer (WCLC), organized by the International Association for the Study of Lung Cancer (IASLC).

Diagnostic tools and innovative therapies improve patient prognosis

SAN FRANCISCO, August 2, 2009 -- The world's top lung cancer specialists, medical professionals and researchers are convening this week in San Francisco, CA for the 13th World Conference on Lung Cancer (WCLC), organized by the International Association for the Study of Lung Cancer (IASLC).

Fox Chase finds all-biologic regimen efficacious and well-tolerated in elderly lung cancer patients

SAN FRANCISCO (August 1, 2009) -- Previously untreated non-small cell lung cancer (NSCLC) patients over the age of 70 respond well to a combination of bevacizumab and erlotinib, Fox Chase Cancer Center researchers reported today at the annual meeting of the International Association for the Study of Lung Cancer.

Fox Chase researchers identify differences in treatments and outcomes of patients with second primary lung cancers versus those with one primary lung cancer

SAN FRANCISCO (August 1, 2009) -- Patients with second primary lung cancers (SPLC), when compared to those with one primary lung cancer (OPLC), are more likely to have localized disease at the time of diagnosis and are more likely to receive surgical treatment rather than radiation treatment.

Advanced targeted therapies effective as first-line treatment for lung cancer

SAN FRANCISCO, August 1, 2009 -- The world's top lung cancer specialists, medical professionals and researchers are convening this week in San Francisco, CA for the 13th World Conference on Lung Cancer (WCLC), organized by the International Association for the Study of Lung Cancer (IASLC).

New lung cancer staging system revealed

For the first time in more than 10 years, the universally accepted lung cancer staging system has been revised to more accurately reflect the prognosis for patients with non-small cell lung cancer (NSCLC).

Defeating nicotine's double role in lung cancer

A lung cancer treatment that inhibits nicotine receptors was shown to double survival time in mice, according to Italian researchers.

The results of the early phase animal model study were reported in the June 15 issue of the American Journal of Respiratory and Critical Care Medicine.

Study shows drug combination improves outcome for advanced non-small cell lung cancer

A new, international study found that the combination of two drugs delays disease progression for patients with advanced non-small cell lung cancer (NSCLC). Results from the Phase III "ATLAS" trial were presented today by Dr. Vincent Miller of Memorial Sloan-Kettering Cancer Center (MSKCC) at the American Society of Clinical Oncology Annual Meeting.

Herceptin gives disappointing results in lung cancer trial

Trastuzumab (Herceptin) ? a treatment that has increased survival in many breast cancer patients ? has failed to live up to hopes that it might also help lung cancer patients. In a Phase II trial of over 100 patients with non-small-cell lung cancer (NSCLC) reported in Annals of Oncology, those treated with trastuzumab in combination with two chemotherapy agents gemcitabine and cisplatin, did no better than patients treated with gemcitabine and cisplatin alone.

Vaccine technique shows potential against common form of lung cancer

In a demonstration of vaccine therapy's potential for treating lung cancer, scientists report that a prototype vaccine boosted the natural immune response to tumors in a small group of patients with advanced non-small cell lung cancer (NSCLC). Moreover, the vaccine was found to be non-toxic and well-tolerated. Published in the Feb. 15 issue of the Journal of Clinical Oncology, findings from the Phase I clinical trial will provide an impetus for further efforts to develop a vaccine against NSCLC, a difficult-to-treat condition that accounts for roughly 80 percent of all lung cancer cases.



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