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Perceived cancer risks may not reflect actual risks or prevention needs

ORLANDO (May 14, 2009)--Working with a population of individuals at risk for gastrointestinal cancers, researchers at Fox Chase Cancer Center have learned that many people misjudge their actual degree of cancer risk and, therefore, their true need for prevention support.

Recent developments at Burnham Institute for Medical Research, May 2009

Human monoclonal antibodies effective against bird and seasonal flu viruses

Women 10 times more likely to do breast self-exams correctly with intervention, KP study finds

April 30, 2009 (Portland, Ore.) A brief intervention program - consisting of one counseling session and two follow-up phone calls - boosted by tenfold the number of women correctly performing breast self- exams. These are the findings of a Kaiser Permanente Center for Health Research study in the American Journal of Health Promotion.

Tips from the American Journal of Pathology

Notch1 Contributes to Scar Tissue in the Lungs

A group led by Dr. Sem Phan at the University of Michigan, Ann Arbor identified Notch1 as a mediator of lung fibrosis. They present their data in the May 2009 issue of The American Journal of Pathology.

Dark hair? Don't burn? Your genes may still put you at risk for melanoma

DENVER - New genetic research suggests that the traditional risk factors for melanoma may not be as helpful in predicting risk in all people as previously thought, according to data presented at th

Brain metastases hijack neuron-supporting cells to resist chemotherapy

DENVER ? Cancer that spreads to other organs finds a particularly inviting hideout in the brain, where these metastases are usually far harder to treat than they are in other locations. Two researchers from The University of Texas M. D.

New therapeutic target for melanoma identified

(PHILADELPHIA) A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research.

New method for detection of phosphoproteins reveals regulator of melanoma invasion

Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events.

Skin cancer study uncovers new tumor suppressor gene

National Institutes of Health (NIH) researchers have identified a gene that suppresses tumor growth in melanoma, the deadliest form of skin cancer. The finding is reported today in the journal Nature Genetics as part of a systematic genetic analysis of a group of enzymes implicated in skin cancer and many other types of cancer.

Hollow gold nanospheres show promise for biomedical and other applications

SALT LAKE CITY, UT--A new metal nanostructure developed by researchers at the University of California, Santa Cruz, has already shown promise in cancer therapy studies and could be used for chemical and biological sensors and other applications as well.

Scientists create mouse model of melanoma that generates hope for the use of targeted therapies

Researchers have developed a new mouse model that allows them to replicate normal pigment cells at the earliest stages of conversion to malignant skin cancer in humans. After testing the mouse with a combination of two drug therapies, the team found the treatment caused a statistically significant regression in cancer cell development.

A new measure for the malignancy of melanoma

Every tumor, starting from a size of a few millimeters, depends on a supply of nutrients and oxygen. Therefore, using special growth factors, it induces vascular wall cells of neighboring blood vessels to sprout new capillaries in order to get connected to the blood circulation.

Drug combination may be effective against deadly melanoma, pilot study shows

By targeting and disabling a protein frequently found in melanoma tumors, doctors may be able to make the cancer more vulnerable to chemotherapy, according to early results of a clinical study conducted by researchers in the Duke Comprehensive Cancer Center.

Scientists engineer new type of vaccination that provides instant immunity

A team of scientists at the Scripps Research Institute has found a way to use specially programmed chemicals to elicit an immediate immune response in laboratory animals against two types of cancer.

Vegetable-based drug could inhibit melanoma

Compounds extracted from green vegetables such as broccoli and cabbage could be a potent drug against melanoma, according to cancer researchers. Tests on mice suggest that these compounds, when combined with selenium, target tumors more safely and effectively than conventional therapy.



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