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NEDD9 protein supports growth of aggressive breast cancer

Researchers at Fox Chase Cancer Center have demonstrated that a protein called NEDD9 may be required for some of the most aggressive forms of breast cancer to grow. Their findings, based on the study of a mouse model of breast cancer, are presented in a recent issue of Cancer Research, available on-line now.

Combination of PET/CT tests can expedite diagnosis of lung cancer in a fast-track setting

Research published in the October 2009 issue of the Journal of Thoracic Oncology has found an effective combination of positron emission tomography (PET)/computed tomography (CT) (PET/CT) tests to diagnose lung cancer in a "fast-tracked" outpatient setting. This novel approach to the diagnosis of lung cancer demonstrated a high level of sensitivity (97%) and accuracy (82%).

Lung cancer risk increases with expression of specific genes

AURORA, COLO -- A recent study published in the October 2009 issue of the Journal of Thoracic Oncology determined that variations of specific genetic markers identified in previous research, or SNPs, may indicate a greater lung cancer risk in African Americans than in whites.

Penn study asks, protection or peril? Gun possession of questionable value in an assault

PHILADELPHIA -- In a first-of its-kind study, epidemiologists at the University of Pennsylvania School of Medicine found that, on average, guns did not protect those who possessed them from being shot in an assault. The study estimated that people with a gun were 4.5 times more likely to be shot in an assault than those not possessing a gun.

Study in Spain and Romania confirms radon as second leading cause of lung cancer

Exposure to radon gas in homes is the second leading cause of lung cancer after smoking, according to a study carried out by researchers from the University of Cantabria and the Babes-Bolyai University in Romania. The team has studied data on exposure to this element in a uranium mining area in Transylvania and in an area of granite in Torrelodones, Madrid.

Certain cancers more common among HIV patients than non-HIV patients

DALLAS -- Sept. 25, 2009 -- Researchers at UT Southwestern Medical Center have found that non-AIDS-defining malignancies such as anal and lung cancer have become more prevalent among HIV-infected patients than non-HIV patients since the introduction of anti-retroviral therapies in the mid-1990s.

M. D. Anderson examines use of toad venom in cancer treatment

HOUSTON - Huachansu, a Chinese medicine that comes from the dried venom secreted by the skin glands of toads, has tolerable toxicity levels, even at doses eight times those normally administered, and may slow disease progression in some cancer patients, say researchers from The University of Texas M. D. Anderson Cancer Center.

New cancer drug test promises safer and more effective clinical trials

Berlin, Germany: A group of scientists from Hamburg may have taken a big step towards more effective cancer drug development, Europe's largest cancer congress, ECCO 15 -- ESMO 34 [1], heard today (Wednesday 23 September).

Prostate cancer patients on hormone therapy at increased risk for various heart diseases

Berlin, Germany: New research has found that hormone therapy used to treat men with advanced prostate cancer is associated with an increased chance of developing various heart problems. Some choices of therapy appear, however, to be less risky than others.

Banning smoking in public places and workplaces is good for the heart

Public smoking bans appear to significantly reduce the risk of heart attacks, particularly among younger individuals and nonsmokers, according to a new study published in the September 29, 2009, issue of the Journal of the American College of Cardiology. Researchers find that smoking bans can reduce the number of heart attacks by as much as 26 percent per year.

Adding cetuximab to chemotherapy reduces advanced lung cancer death risk by 13 percent

Berlin, Germany: Patients with advanced non-small cell lung cancer who are given cetuximab (Erbitux) in addition to chemotherapy are 13% less likely to die than those who receive chemotherapy alone, regardless of which chemotherapy drug cocktail is used, new research finds. They also experience slower disease progression and an increased chance of tumour shrinkage.

Whole-brain radiotherapy after surgery or radiosurgery not recommended for brain metastases

Berlin, Germany: Whole-brain radiotherapy should not be given routinely to all patients whose cancer has spread to the brain, say researchers who found that using it after surgery or radiosurgery in patients with a limited number of brain metastases and stable cancer in the rest of the body did not extend lives or help patients remain functionally independent for longer.

Guide on lung cancer in 'never-smokers': A different disease and different treatments

A committee of scientists led by Johns Hopkins investigators has published a new guide to the biology, diagnosis and treatment of lung cancer in never-smokers, fortifying measures for what physicians have long known is a very different disease than in smokers.

Lung cancer suppresses miR-200 to invade and spread

HOUSTON - Primary lung cancer shifts to metastatic disease by suppressing a family of small molecules that normally locks the tumor in a noninvasive state, researchers at The University of Texas M. D. Anderson Cancer Center report in the Sept. 15 edition of Genes and Development.

Mayo Clinic researchers find lung cancer oncogene holds key to turning off cancer stem cells

JACKSONVILLE, Fla. -- Scientists at the Mayo Clinic campus in Florida have found that the lung cancer oncogene PKCiota is necessary for the proliferation of lung cancer stem cells. These stem cells are rare and powerful master cells that manufacture the other cells that make up lung tumors and are resistant to chemotherapy treatment.



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