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Alarming trend -- antiviral therapy to treat hepatitis C is declining in the US

Researchers from the University of Michigan determined that only 663,000 of the approximately 3.9 million Americans with hepatitis C virus (HCV) infection received antiviral therapy between 2002 and 2007. Treatment rates appear to be declining, in part because only half of the patients know they are infected.

Researchers identify role of gene in tumor development, growth and progression

RICHMOND, Va. (Nov. 20, 2009) -- Virginia Commonwealth University Massey Cancer Center and VCU Institute of Molecular Medicine researchers have identified a gene that may play a pivotal role in two processes that are essential for tumor development, growth and progression to metastasis.

1 disease, not 1 demographic

The Asian continent has nearly four billion people living in 47 different countries, and each of these groups has their own unique set of health issues.

Protein interaction network can respond Helicobacter pylori infection?

Helicobacter pylori (H pylori) is a gram negative bacterium which infects about 50% of the world population. H pylori colonization causes a strong systemic immune response. Various tools have been employed to identify the relationship between H pylori and gastric cancer, including c-DNA microarrays.

How to identify early graft dysfunction preoperatively?

Small-for-size graft dysfunction (SFSGD) following living-related liver transplantation (LRLT) is characterized by early graft dysfunction (EGD) when the graft-to-recipient body weight ratio (GRBWR) is below 0.8%. However, patients transplanted with GRBWR above 0.8% can develop dysfunction of the graft.

A case of post-gastrectomy acute pancreatitis

Gastrectomy is commonly performed for both benign and malignant lesions. Although the incidence of post-gastrectomy acute pancreatitis (PGAP) is low compared to other well-recognized post-operative complications, it has been reported to be associated with a high mortality rate.

First-of-kind study shows model can be used to rate courtroom psychiatric experts performance

Court cases across America often feature expert testimony that offers conflicting conclusions. When this happens in cases involving psychiatric expertise, does it mean that one side or the other is necessarily being less than honest?

Parasite growth hormone pushes human cells to liver cancer

Scientists have found that the human liver fluke (Opisthorchis viverrini) contributes to the development of bile duct (liver) cancer by secreting granulin, a growth hormone that is known to cause uncontrolled growth of cells. Details are published October 9 in the open-access journal PLoS Pathogens.

Elevated lymphotoxin expression in liver leads to chronic hepatitis and causes HCC

A recent study maps the pathway that leads from infection with Hepatitis B and C virus (HBV and HCV) to chronic hepatitis and liver cancer and proposes a new therapeutic strategy for treating liver diseases with chronic inflammation.

Certain cancers more common among HIV patients than non-HIV patients

DALLAS -- Sept. 25, 2009 -- Researchers at UT Southwestern Medical Center have found that non-AIDS-defining malignancies such as anal and lung cancer have become more prevalent among HIV-infected patients than non-HIV patients since the introduction of anti-retroviral therapies in the mid-1990s.

M. D. Anderson examines use of toad venom in cancer treatment

HOUSTON - Huachansu, a Chinese medicine that comes from the dried venom secreted by the skin glands of toads, has tolerable toxicity levels, even at doses eight times those normally administered, and may slow disease progression in some cancer patients, say researchers from The University of Texas M. D. Anderson Cancer Center.

Sorafenib significantly improves the length of time before breast cancer worsens

Berlin, Germany: One of the first of a series of trials to investigate the use of sorafenib -- a targeted anti-cancer drug -- for the treatment of advanced breast cancer has found that if it is combined with the chemotherapy drug, capecitabine, it makes a significant difference to the time women live without their disease worsening.

Penn State College of Medicine research isolates liver cancer stem cells prior to tumor formation

HERSHEY, PA -- Penn State College of Medicine researchers, in collaboration with colleagues at the University of Southern California, have taken an important step in understanding the role of stem cells in development of liver cancer. Using a unique approach that involves study of individual cells, the team, led by C.

Evaluation of standard liver volume formula for Chinese adults

Living donor liver transplantation (LDLT) has been used to alleviate the shortage of available liver donors. Accurate estimation of the standard liver volume (SLV) of the living donor and recipient is crucial. Scholars of different countries established several SLV formulae from clinical data, but which formula was the most accurate for Chinese adults has remained unclear.

How to reach proficiency in laparoscopic splenectomy?

Laparoscopic splenectomy has become the gold standard intervention for the removal of the spleen, especially for benign causes. However, the organ's high anatomic location, fragility and generous blood supply makes the procedure an advanced laparoscopic operation. Furthermore, unlike patients with gall bladder stones, patients who need splenectomy for benign disorders are rare.



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