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Drug therapy more cost-effective than angioplasty for diabetic patients with heart disease

November 17, 2009

STANFORD, Calif. -- Many patients with diabetes should forego angioplasties for heart disease and just take medicine instead, according to a new National Institutes of Health study led by Stanford University School of Medicine researcher Mark Hlatky, MD.

Common herbicides and fibrates block nutrient-sensing receptor found in gut and pancreas

October 9, 2009

PHILADELPHIA (October 09, 2009) -- According to new research from the Monell Center and the Mount Sinai School of Medicine, certain common herbicides and lipid-lowering fibrate drugs act in humans to block T1R3, a nutrient-sensing taste receptor also present in intestine and pancreas.

Link found between depression, early stages of chronic kidney disease

September 8, 2009

DALLAS -- Sept. 8, 2009 -- One in five patients with chronic kidney disease is depressed, even before beginning long-term dialysis therapy or developing end-stage renal disease, UT Southwestern Medical Center researchers have found.

U-M researchers discover therapeutic target that could help patients with pulmonary fibrosis

August 23, 2009

ANN ARBOR, Mich. -- A diagnosis of Idiopathic Pulmonary Fibrosis is not much better than a death sentence: there is no treatment and the survival rate is less than three years.

From nerve roots to plant roots -- research on hereditary spastic paraplegia yields surprises

August 6, 2009

Sprouting. Branching. Pruning. Neuroscientists have borrowed heavily from botanists to describe the way that neurons grow, but analogies between the growth of neurons and plants may be more than superficial. A new study from the National Institutes of Health and Harvard Medical School suggests that neurons and plant root cells may grow using a similar mechanism.

New statistical method shows importance of dialysis dose

July 30, 2009

A new approach to statistical analysis may be better suited to study the relationship between higher "dose" of dialysis and survival time for patients with advanced kidney disease, according to an upcoming paper in the Journal of the American Society of Nephrology (JASN).

Chronic kidney disease profoundly impacts quality of life

July 30, 2009

Chronic kidney disease (CKD) can significantly lessen patients' quality of life, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Certain types of patients -- women, diabetics, and those with a history of heart complications -- are most affected.

NIH study finds low short-term risks after bariatric surgery for extreme obesity

July 30, 2009

Short-term complications and death rates were low following bariatric surgery to limit the amount of food that can enter the stomach, decrease absorption of food or both, according to the Longitudinal Assessment of Bariatric Surgery (LABS-1). The study was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.

New lab test helps predict kidney damage

July 23, 2009

Acute kidney injury (AKI) is a frequent complication in patients in intensive care. A new laboratory test called urine neutrophil gelatinase associated lipocalin (NGAL) helps predict if patients will develop acute kidney injury, reports an upcoming study in the Journal of the American Society of Nephrology (JASN).

Protein excreted in urine may be help in diagnosing kidney disease caused by HIV

July 23, 2009

NEW YORK -- New data collected at Columbia University Medical Center and by the Mount Sinai School of Medicine are helping researchers understand the extent to which a certain protein -- NGAL -- can play a significant role in marking chronic kidney disease resulting from HIV while at the same time distinguishing nephropathy from more common causes such as diabetes and hypertension.

Scripps research studies lead to a promising first-in-class drug candidate

July 21, 2009

LA JOLLA, CA, July 21, 2009 -- -- Discoveries by Scripps Research Institute scientists have led to a promising new drug candidate -- the first in its class -- for patients with a genetic protein-misfolding disease. In results announced by the biopharmaceutical firm FoldRx Pharmaceuticals, Inc.

Underweight and extremely obese die earlier than people of normal weight, study finds

June 23, 2009

Underweight people and those who are extremely obese die earlier than people of normal weight -- but those who are overweight actually live longer than people of normal weight.

IUPUI study finds living near fast food outlet not a weighty problem for kids

June 16, 2009

INDIANAPOLIS -- A new study by Indiana University-Purdue University Indianapolis (IUPUI) researchers contradicts the conventional wisdom that living near a fast food outlet increases weight in children and that living near supermarkets, which sell fresh fruit and vegetables as well as so called junk food, lowers weight.

Jefferson Appoints Vice Dean for Research

June 15, 2009

Leonard P. Freedman, Ph.D., recently joined Jefferson Medical College of Thomas Jefferson University in the newly created position of Vice Dean for Research. In this role, Dr.



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