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High-sugar diet increases men's blood pressure; gout drug protective

A high-fructose diet raises blood pressure in men, while a drug used to treat gout seems to protect against the blood pressure increase, according to research reported at the American Heart Association's 63rd High Blood Pressure Research Conference.

"This is the first evidence of a role of fructose in raising blood pressure and a role for lowering uric acid to protect against that blood pr

Metabolic syndrome risk factors drive significantly higher health care costs

New Rochelle, NY, September 17, 2009 -- Risk factors for metabolic syndrome, such as obesity, high blood pressure, and elevated blood lipid levels, can increase a person's healthcare costs nearly 1.6-fold, or about $2,000 per year.

Insulin, metformin do not reduce inflammatory biomarkers for diabetes patients

CHICAGO -- In patients with recent onset type-2 diabetes, treatment with insulin or the diabetes drug metformin did not reduce inflammatory biomarkers, such as high-sensitivity C-reactive protein, although the treatment did improve glucose control, according to a study in the September 16 issue of JAMA.

Ice cream may target the brain before your hips, UT Southwestern study suggests

DALLAS -- Sept. 14, 2009 -- Blame your brain for sabotaging your efforts to get back on track after splurging on an extra scoop of ice cream or that second burger during Friday night's football game.

University of Hawaii at Manoa CRCH scientists report adulthood body size associated with cancer risk

A team of scientists led by researcher Brenda Hernandez, Ph.D., M.P.H. -- an assistant professor at the University of Hawai'i at Mānoa's Cancer Research Center of Hawai'i -- has reported that body mass in younger and older adulthood, and weight gain between these life periods, may influence a man's risk for prostate cancer.

Size of fat cells and waist size predict type 2 diabetes in women

When it comes to assessing risk for type 2 diabetes, not only do waistlines matter to women, but so does the size of their fat cells. This new discovery by a team of Swedish researchers was just published online in the FASEB Journal (http://www.fasebj.org) and helps explain why some women of normal weight develop type 2 diabetes, despite not having any known risk factors.

Scientists discover new genetic variation that contributes to diabetes

Scientists have identified a genetic variation in people with type 2 diabetes that affects how the body's muscle cells respond to the hormone insulin, in a new study published today in Nature Genetics. The researchers, from Imperial College London and other international institutions, say the findings highlight a new target for scientists developing treatments for diabetes.

Mice can eat 'junk' and not get fat

A study in the September 4th issue of the journal Cell, a Cell Press publication, identifies a gene that springs into action in response to a high fat diet. Mice that lack the gene become essentially immune to growing obese, regardless of their eating habits.

U-M researchers find gene that protects high-fat-diet mice from obesity

ANN ARBOR, Mich.---University of Michigan researchers have identified a gene that acts as a master switch to control obesity in mice. When the switch is turned off, even high-fat-diet mice remain thin.

From fat to chronic inflammation

Researchers may have found a key ingredient in the recipe that leads from obesity to chronic low-grade inflammation, according to a report in the September issue of Cell Metabolism, a Cell Press publication.

Weight-loss surgery can break a family's cycle of obesity

Chevy Chase, MD -- Adolescent and young children of obese mothers who underwent weight-loss surgery prior to pregnancy have been found to have a lower prevalence of obesity and significantly improved cardio-metabolic markers when compared to siblings born before the same obese mothers had weight-loss surgery.

Childhood obesity: The increasing vascular drama

Barcelona, Spain, 31 August: Obesity is one of the most important health problems in industrialized countries irrespective of socio-economic status, age, sex or ethnicity. The prevalence of childhood obesity in children has reached alarming levels, even in developing countries.

'Fatostatin' is a turnoff for fat genes

A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell Press journal.

Pitt study finds molecular link between insulin resistance and inflammation

PITTSBURGH, Aug. 26 -- An exploration of the molecular links between insulin resistance and inflammation may have revealed a novel target for diabetes treatment, say scientists at the John G. Rangos Sr. Research Center, Children's Hospital of Pittsburgh of UPMC.

Fat in the liver -- not the belly -- is a better marker for disease risk

New findings from nutrition researchers at Washington University School of Medicine in St. Louis suggest that it's not whether body fat is stored in the belly that affects metabolic risk factors for diabetes, high blood triglycerides and cardiovascular disease, but whether it collects in the liver.



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