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Largest gene study of childhood IBD identifies 5 new genes

November 15, 2009

In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in a biological pathway that helps drive the painful inflammation of the digestive tract that characterizes the disease.

M. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers

October 26, 2009

HOUSTON - Drawing on years of experience in cancer research and patient care, The University of Texas M. D.

Study reveals possible link between IBD therapy and skin cancer

October 26, 2009

San Diego, CA (October 26, 2009) -- Findings from a new retrospective cohort study presented at the American College of Gastroenterology's 74th Annual Scientific meeting in San Diego indicate tha

Discovery of genetic defect may lead to better treatments for common gut diseases

October 8, 2009

INDIANAPOLIS -- New findings related to an uncommon genetic disorder may impact the diagnosis and treatment of inflammatory bowel disease (IBD), the most common chronic gastrointestinal illness in children and teens. Two million Americans have IBD which involves inflammation of the gastrointestinal tract.

Ulcerative colitis treatment reduces need for surgery by almost half

September 30, 2009

ROCHESTER, Minn -- A new study led by Mayo Clinic researchers has found that ulcerative colitis patients had a 41 percent reduction in colectomy after a year when treated with infliximab, according to a study published in the October 2009 issue of Gastroenterology.

Visionary concept earns La Jolla Institute scientist prestigious NIH Pioneer Award

September 24, 2009

SAN DIEGO -- (September 24, 2009) A scientist at the La Jolla Institute for Allergy & Immunology has received one of the National Institutes of Health (NIH)'s top awards -- the 2009 NIH Director's Pioneer Award.

Promising new target emerges for autoimmune diseases

September 1, 2009

ANN ARBOR, Mich. -- University of Michigan scientists say they have uncovered a fundamentally new mechanism that holds in check aggressive immune cells that can attack the body's own cells. The findings open a new avenue of research for future therapies for conditions ranging from autoimmune diseases to organ transplants to cancer.

Researchers find high-dose therapy for liver disease not effective

August 28, 2009

ROCHESTER, Minn. -- A national team of researchers led by scientists at Mayo Clinic has found that a common treatment for primary sclerosing cholangitis, a chronic liver disease, is not helpful for patients, according to a study published this month in the journal Hepatology.

Resolvyx announces positive data -- Phase 2 trial of resolvin RX-10045 for dry eye syndrome

August 24, 2009

BEDFORD, MA ?August, 24, 2009 -- Resolvyx Pharmaceuticals, Inc., the leading resolvin therapeutics company, today announced positive data from a Phase 2 clinical study evaluating RX-10045, a resolvin administered as a topical eye drop for the treatment of patients with chronic dry eye syndrome.

Genetically engineered bacteria are sweet success against IBD

August 20, 2009

For the first time, scientists have used a genetically engineered "friendly" bacterium to deliver a therapy.

Study finds adverse effects in treatment for primary sclerosing cholangitis

August 19, 2009

Primary sclerosing cholangitis (PSC) is an uncommon chronic liver disease characterized by progressive inflammation and destruction of the bile ducts. The disease progresses slowly, usually leading to biliary cirrhosis, portal hypertension and liver failure over a 10-15 year period.

Budesonide is not beneficial for the treatment of diarrhea in metastatic melanoma patients

August 11, 2009

PHILADELPHIA -- Patients with stage III or IV melanoma taking ipilimumab and the oral steroid budesonide to reduce side effects did not have less diarrhea, a known side effect of ipilimumab, according to results of a phase II trial published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Pinpointing cause of colic: UT Houston researchers identify organism

July 24, 2009

Researchers at The University of Texas Health Science Center at Houston say one organism discovered during their study may unlock the key to what causes colic, inconsolable crying in an otherwise healthy baby.

Novel genetic finding offers new avenue for future Crohn's disease treatment

July 9, 2009

Researchers from Case Western Reserve University School of Medicine identified a novel link between ITCH, a gene known to regulate inflammation in the body and NOD2, a gene which causes the majority of genetic Crohn's Disease diagnoses.



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