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New lab test helps predict kidney damage

Acute kidney injury (AKI) is a frequent complication in patients in intensive care. A new laboratory test called urine neutrophil gelatinase associated lipocalin (NGAL) helps predict if patients will develop acute kidney injury, reports an upcoming study in the Journal of the American Society of Nephrology (JASN).

Protein excreted in urine may be help in diagnosing kidney disease caused by HIV

NEW YORK -- New data collected at Columbia University Medical Center and by the Mount Sinai School of Medicine are helping researchers understand the extent to which a certain protein -- NGAL -- can play a significant role in marking chronic kidney disease resulting from HIV while at the same time distinguishing nephropathy from more common causes such as diabetes and hypertension.

HIV infection and chronic drinking have a synergistic, damaging effect on the brain

More than half of clinic patients infected with the human immunodeficiency virus (HIV) report they also drink heavily. While highly active antiretroviral therapy has helped to reduce HIV-related cognitive and motor deficits, neuropsychological deficits may continue and even be exacerbated by alcohol.

Hepatitis C infection: treatment options equally effective, likelihood of success known early on

Results of a long-awaited study of 3,070 American adults at Johns Hopkins and 118 other U.S. medical centers show that treatment with either of the two standard antiviral drug therapies is safe and offers the best way for people infected with hepatitis C to prevent liver scarring, organ failure and death.

LSUHSC's Martin says syphilis making comeback, gonorrhea more treatment resistant

New Orleans, LA -- Dr. David H. Martin, Professor and Chief of the Section of Infectious Diseases at LSU Health Sciences Center New Orleans School of Medicine, updated reporters and the National Foundation for Infectious Diseases on sexually transmitted diseases in the United States on July 22, 2009 at the National Press Club in Washington , DC. Dr.

AIDS discovered in wild chimpanzees

Although the AIDS virus (HIV-1) entered the human population through chimpanzees, scientists have long believed that chimpanzees don't develop AIDS.

New evidence: AIDS-like disease in wild chimpanzees

Chicago -- An international consortium has found that wild chimpanzees naturally infected with Simian Immunodeficiency Viruses (SIV) -- long thought to be harmless to the apes -- can contract an AIDS-like syndrome and die as a result. The findings are published in the July 23 edition of the journal Nature.

Yerkes plays vital role in study challenging prevailing view of AIDS in nonhuman primates

Researchers at Yerkes National Primate Research Center, Emory University, contributed key comparative data for a landmark study showing African wild chimpanzees infected with simian immunodeficiency virus (SIV), an HIV-1-like virus, die prematurely and develop hallmarks of HIV-1 infection and AIDS.

Pre-chewed food could transmit HIV

(MEMPHIS, Tenn. -- July 21, 2009) Researchers have uncovered the first cases in which HIV almost certainly was transmitted from mothers or other caregivers to children through pre-chewed food. The source of HIV in the pre-chewed food was most likely the infected blood in the saliva of the people who pre-chewed the food before giving it to the children.

New method for HIV testing holds promise for developing world

DURHAM, NC -- A new technique that detects the HIV virus early and monitors its development without requiring refrigeration may make AIDS testing more accessible in sub-Saharan Africa.

Embargoed news from Annals of Internal Medicine

HIV Susceptibility Testing Increases Patient Survival

Study offers insights into failed HIV-1 vaccine trial

BOSTON -- Following the disbandment of the STEP trial to test the efficacy of the Merck HIV-1 vaccine candidate in 2007, the leading explanation for why the vaccine was ineffective -- and may have even increased susceptibility to acquiring the virus -- centered on the hypothesis that high levels of baseline Ad5-specific neutralizing antibodies may have increased HIV-1 acquisition among the s

No race disparities in risk of AIDS and death in HIV patients in Kaiser Permanente system

OAKLAND, Calif., July 20, 2009 -- Kaiser Permanente researchers found no disparities by race or ethnicity in risk of AIDS and death among HIV-infected patients in a setting of similar access to care. This is despite lower Anti-Retroviral Therapy adherence among Hispanics and African-Americans compared to whites. Researchers also saw a trend toward better outcomes for Hispanics.

Earlier HIV antiviral treatment can be cost effective in areas of limited resources

Early initiation of lifesaving antiretroviral therapies should be the standard of care for all HIV-infected patients, even those in countries with limited medical and financial resources, according to a study led by researchers at Massachusetts General Hospital (MGH) and the Desmond Tutu HIV Centre, University of Cape Town, South Africa.

Penn-Wistar team gains insight into HIV vaccine failure

PHILADELPHIA -- (July 20, 2009) -- A team of researchers from The Wistar Institute and the University of Pennsylvania reports new evidence refuting a popular hypothesis about the highly publicized failure in 2007 of the Merck STEP HIV vaccine study that cast doubt on the feasibility of HIV-1 vaccines. The findings were published on-line July 20 in Nature Medicine.



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