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Engineered protein-like molecule protects cells against HIV infection

MADISON -- With the help of the human immunodeficiency virus (HIV) and molecular engineering, researchers have designed synthetic protein-like mimics convincing enough to interrupt unwanted biological conversations between cells.

Updated guidelines highlight primary care needs of those living with HIV

Arlington, Va. -- With HIV patients living longer thanks to advances in treatment, the primary care needs of those living with HIV have never been more important. Updated, evidence-based guidelines from the HIV Medicine Association (HIVMA) and the Infectious Diseases Society of America (IDSA) are designed to help providers manage the care of those living with this complex chronic infection.

HIV integrase inhibitor effective for patients beginning antiretroviral treatment

A member of a new class of antiretroviral drugs is safe and effective for patients beginning treatment against HIV, according to researchers who have completed a two-year multisite phase III clinical trial comparing it with standard antiretroviral drugs.

The results are online and scheduled for publication in an upcoming issue of the Lancet.

Scientists learn why even treated genital herpes sores boost the risk of HIV infection

New research helps explain why infection with herpes simplex virus-2 (HSV-2), which causes genital herpes, increases the risk for HIV infection even after successful treatment heals the genital skin sores and breaks that often result from HSV-2.

Mayo researchers find race has role in incidence, survival of rare brain tumor

ROCHESTER, Minn. -- The incidence of a rare and deadly tumor called primary central nervous system lymphoma (PCNSL) is two times higher in black Americans, ages 20 to 49, than in white Americans, according to a Mayo Clinic study published in the June issue of Journal of Neuro-Oncology. In patients older than 49, the results were reversed.

HIV infection and chronic drinking have a synergistic, damaging effect on the brain

More than half of clinic patients infected with the human immunodeficiency virus (HIV) report they also drink heavily. While highly active antiretroviral therapy has helped to reduce HIV-related cognitive and motor deficits, neuropsychological deficits may continue and even be exacerbated by alcohol.

New method for HIV testing holds promise for developing world

DURHAM, NC -- A new technique that detects the HIV virus early and monitors its development without requiring refrigeration may make AIDS testing more accessible in sub-Saharan Africa.

Earlier HIV antiviral treatment can be cost effective in areas of limited resources

Early initiation of lifesaving antiretroviral therapies should be the standard of care for all HIV-infected patients, even those in countries with limited medical and financial resources, according to a study led by researchers at Massachusetts General Hospital (MGH) and the Desmond Tutu HIV Centre, University of Cape Town, South Africa.

Penn-Wistar team gains insight into HIV vaccine failure

PHILADELPHIA -- (July 20, 2009) -- A team of researchers from The Wistar Institute and the University of Pennsylvania reports new evidence refuting a popular hypothesis about the highly publicized failure in 2007 of the Merck STEP HIV vaccine study that cast doubt on the feasibility of HIV-1 vaccines. The findings were published on-line July 20 in Nature Medicine.

Risky sexual behavior among male clients of Tijuana sex workers heightens risk of HIV transmission

A study by a bi-national team of global health researchers at the University of California, San Diego School of Medicine, examining HIV infection among male clients of female sex workers in Tijuana, has found that over half of male clients had recently had unprotected sex. They also reported a high prevalence of drug use.

New lab test offers better prediction of HIV microbicide safety

July 9, 2009 -- (BRONX, NY) -- Scientists at Albert Einstein College of Medicine of Yeshiva University have devised a laboratory test for predicting whether microbicides against HIV are safe for human use. The researchers have also discovered why several supposedly "safe" microbicides made women more susceptible to HIV infection.

Researchers uncover approach for possibly eradicating HIV infection

ST. LUCIE, FL -- Researchers from the newly-established VGTI Florida and the University of Montreal have uncovered a possible method for eradicating HIV infection in the human body.

Predicting fatal fungal infections

June 15, 2009 -- (BRONX, NY) -- In a study published in The Journal of Infectious Diseases, researchers from Albert Einstein College of Medicine of Yeshiva University have identified cells in blood that predict which HIV-positive individuals are most likely to develop deadly fungal meningitis, a major cause of HIV-related death.

New study reveals structure of the HIV protein shell

LA JOLLA, CA, June 12, 2009 -- New research by scientists at The Scripps Research Institute and other institutions provides a close-up look at the cone-shaped shell that is the hallmark of human immunodeficiency virus (HIV), revealing how it is held together -- and possible ways to break it apart.

NIAID leaders outline research agenda for universal, voluntary HIV testing and treatment

Could a global program of universal, voluntary, annual HIV testing and immediate treatment for those who test positive effectively extinguish the HIV pandemic? Is such a program feasible?



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