hepatitis
The intraductal papillary mucinous neoplasms (IPMN) can evolve through all biological stages, from slight dysplasia to carcinoma. As one of the few surgically curable pancreatic tumors, accurate preoperative prediction of malignancy remains one of the major issues in the optimal treatment of IPMNs, and it also influences the outcome of the resection.
Yes-associated protein (YAP) is a type of cellular adaptor protein and transcriptional co-activator. In recent years, some investigators have found YAP to be overexpressed and highly activated in hepatic cancers and mammary cancers, suggesting its tumorigenicity.
CHAPEL HILL, N.C. -- Researchers at the University of North Carolina at Chapel Hill have discovered a genetic risk factor for severe liver disease in people with cystic fibrosis.
Bethesda, MD (Sept. 1, 2009) -- Sexual impairment is common among men with chronic hepatitis C undergoing antiviral therapy, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.
WASHINGTON, Aug. 16, 2009 -- The first dry powder inhalable vaccine for measles is moving toward clinical trials next year in India, where the disease still sickens millions of infants and children and kills almost 200,000 annually, according to a report presented here today at the 238th National Meeting of the American Chemical Society (ACS).
DURHAM, N.C. -- Researchers have identified the first genetic marker that predicts response to hepatitis C treatments, and a single letter of DNA code appears to make a huge difference.
Recently, the number of patients with GERD has increased in Japan. However, there have been few reports about the pathological findings in the esophageal squamous epithelium, and there are differing opinions among pathologists about the findings considered characteristic of chronic reflux esophagitis.
Primary sclerosing cholangitis (PSC) is an idiopathic chronic cholestatic inflammatory liver disease characterized by diffuse fibrosing inflammation of intra- and/or extrahepatic bile ducts, resulting in bile duct obliteration, biliary cirrhosis, and eventually hepatic failure.
Using the Vienna classification system, it has been shown in clinic-based cohorts that there can be a significant change in disease behavior over time, whereas disease location remains relatively stable. Clinical and environmental factors as well as medical therapy might be relevant in predicting disease behavior change in patients with CD.
Results of a long-awaited study of 3,070 American adults at Johns Hopkins and 118 other U.S. medical centers show that treatment with either of the two standard antiviral drug therapies is safe and offers the best way for people infected with hepatitis C to prevent liver scarring, organ failure and death.
Researchers at Rice University and their international colleagues have for the first time described the atomic structure of the protein shell that carries the genetic code of hepatitis E (HEV). Their findings, published in the Proceedings of the National Academy of Sciences, could mean that new ways to stop the virus may come in the not-too-distant future.
CHICAGO, IL (June 2, 2009) -- Researchers are making great strides in the development of new treatments for hepatitis and in confirming the effectiveness of current treatments, according to several studies being presented at Digestive Disease Week® 2009 (DDW®).
CHICAGO, IL (May 29, 2009) - A new study is the first to show that there is a previously unrecognized role for environmental pollution in liver disease in the general U.S. adult population. This work builds upon the groups' previous research demonstrating liver disease in highly-exposed chemical workers.
Reperfusion of a previously ischemic tissue is associated with additional injury leading to structural and functional alterations in many organs including the liver. The injury induced during reperfusion is evolved a biphasic pattern consisting of an early stage started upon reoxygenation and a delayed phase.
Nearly every water source in Haiti – rivers, streams, springs and wells – is contaminated with human waste and disease. There are no public sewage treatment or disposal systems anywhere in the country – even in the large cities. The result is a tragedy.