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Duke/Singapore scientists find new way to classify gastric cancers

October 1, 2009

DURHAM, N.C., -- An international team of scientists has discovered a new way to classify stomach cancers, and researchers say it may be an important step toward designing more effective treatments and improving long-term survival.

Stomach (gastric) cancer is particularly prevalent in Asia and represents the second leading cause of cancer deaths worldwide.

New blood tests promise simple, cost-effective diagnosis of gastrointestinal cancers

September 20, 2009

Berlin, Germany: Promising results from two new blood tests that can aid in the early identification of patients with gastrointestinal (GI) cancers will be presented at Europe's largest cancer congress, ECCO 15 -- ESMO 34 [1], in Berlin today (Monday September 21).

Five brain cancers linked to single gene

August 5, 2004

Hotspots in two areas of a gene that encodes a specific signaling enzyme, or kinase, are vulnerable to a variety of mutations found in five types of brain cancers, according to a report published in the August 1 issue of the journal Cancer Research. Mutations in the gene PIK3CA occur spontaneously as part of the brain tumor development rather than being passed genetically between generations, said Hai Yan, M.D., Ph.D., the senior scientist of the studies. ''PIK3CA mutations are known to occur in as much as 30 percent of colorectal and gastric cancers and glioblastomas and they are also present, to a lesser extent, in breast and lung cancer,'' Yan noted. ''Our studies defined the association of mutant PIK3CA gene in a wider spectrum of adult and pediatric brain tumors as well.''



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