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The food-energy cellular connection revealed

Our body's activity levels fall and rise to the beat of our internal drums -- the 24-hour cycles that govern fundamental physiological functions, from sleeping and feeding patterns to the energy available to our cells. Whereas the master clock in the brain is set by light, the pacemakers in peripheral organs are set by food availability. The underlying molecular mechanism was unknown.

New data showed type 2 diabetes patients experienced greater blood sugar reductions

DEERFIELD, Ill., October 14, 2009 -- A study, published online in the journal Current Medical Research and Opinion, showed that a greater percentage of patients with type 2 diabetes treated with the fixed-dose combination ACTOplus met® (pioglitazone HCl and metformin HCl) as initial therapy reached the study goal of hemoglobin A1c (HbA1c) of ≤7 percent compared to either component alone.

UT Southwestern study shows how substance in grapes may squeeze out diabetes

DALLAS -- Oct. 15, 2009 -- A naturally produced molecule called resveratrol, found in the skin of red grapes, has been shown to lower insulin levels in mice when injected directly into the brain, even when the animals ate a high-fat diet.

Suffering caused by dialysis for nursing home seniors may outweigh its benefits, researchers find

STANFORD, Calif. -- Older Americans living in nursing homes experience a significant decline in their ability to perform simple daily tasks -- such as feeding themselves, getting dressed or brushing their teeth -- after starting dialysis, say researchers at the Stanford University School of Medicine.

Tracking down the human 'odorprint'

Each of the 6.7 billion people on Earth has a signature body odor -- the chemical counterpart to fingerprints -- and scientists are tracking down those odiferous arches, loops, and whorls in the "human odorprint" for purposes ranging from disease diagnosis to crime prevention.

Study may explain how a well-known epilepsy and pain drug works

DURHAM, N.C. -- A Duke University Medical Center researcher who spent years looking for the signals that prompt the brain to form new connections between neurons has found one that may explain precisely how a well-known drug for epilepsy and pain actually works.

The finding may also point to new therapies for brain injury and neuropathic pain.

Healthy neighborhoods may be associated with lower diabetes risk

Individuals living in neighborhoods conducive to physical activity and providing access to healthy foods may have a lower risk of developing type 2 diabetes in a five-year period, according to a report in the October 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Common herbicides and fibrates block nutrient-sensing receptor found in gut and pancreas

PHILADELPHIA (October 09, 2009) -- According to new research from the Monell Center and the Mount Sinai School of Medicine, certain common herbicides and lipid-lowering fibrate drugs act in humans to block T1R3, a nutrient-sensing taste receptor also present in intestine and pancreas.

Gene data tool advances prospects for personalized medicine

A sophisticated computational algorithm, applied to a large set of gene markers, has achieved greater accuracy than conventional methods in assessing individual risk for type 1 diabetes.

Shingles raises risk of stroke by 30 percent or more in adults

Adults with shingles were about 30 percent more likely to have a stroke during a one-year follow-up than adults without shingles, in a study reported in Stroke: Journal of the American Heart Association.

The risk was even greater when the infection involved the eyes.

Liver cells grown from patients' skin cells

Scientists at The Medical College of Wisconsin in Milwaukee have successfully produced liver cells from patients' skin cells opening the possibility of treating a wide range of diseases that affect liver function. The study was led by Stephen A. Duncan, D.

Immune cell entry into the pancreatic islets key to understanding type 1 diabetes origins

St. Jude Children's Research Hospital investigators have discovered how destructive immune cells gain access to insulin-producing cells and help cause diabetes.

The finding points to possible new strategies to halt or prevent type I diabetes.

Governor recognizes stem cell research at Einstein

October 8, 2009 -- (BRONX, NY) -- Albert Einstein College of Medicine of Yeshiva University hosted a roundtable discussion on stem cell research with New York Governor David A. Paterson today. Allen M. Spiegel, M.D., the Marilyn and Stanley M.

Autism Speaks' genetic resource exchange, tissue program support findings published in Nature

New York, NY (October 7, 2009) -- Autism Speaks' Autism Genetic Resource Exchange (AGRE) and the Autism Tissue Program (ATP) continue to play an integral role in continuing genetic research and new findings in the complex autism inheritance and causation puzzle.

Jumping genes, gene loss and genome dark matter

In research published today by Nature, an international team describes the finest map of changes to the structure of human genomes and a resource they have developed for researchers worldwide to look at the role of these changes in human disease. They also identify 75 'jumping genes' - regions of our genome that can be found in more than one location in some individuals.



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