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Common herbicides and fibrates block nutrient-sensing receptor found in gut and pancreas

PHILADELPHIA (October 09, 2009) -- According to new research from the Monell Center and the Mount Sinai School of Medicine, certain common herbicides and lipid-lowering fibrate drugs act in humans to block T1R3, a nutrient-sensing taste receptor also present in intestine and pancreas.

Scripps research scientists identify genetic cause for type of deafness

LA JOLLA, CA -- September 1, 2009 ?A team led by scientists from The Scripps Research Institute has discovered a genetic cause of progressive hearing loss. The findings will help scientists better understand the nature of age-related decline in hearing and may lead to new therapies to prevent or treat the condition.

Researchers report gene associated with language, speech and reading disorders

LAWRENCE, KAN. -- A new candidate gene for Specific Language Impairment has been identified by a research team directed by Mabel Rice at the University of Kansas, in collaboration with Shelley Smith, University of Nebraska Medical Center, and Javier Gayán of Neocodex, Seville, Spain.

Gene discovery reveals a critical protein's function in hearing

Discovery of a deafness-causing gene defect in mice has helped identify a new protein that protects sensory cells in the ear, according to a study led by University of Iowa researchers. The findings, which also involved Kansas State University, appear in the Aug. 21 issue of the open-access journal PLoS Genetics.

Tone deaf? blame it on poor connectivity

August 21, 2009 by The Quantum Lob...

The Quantum Lobe Chronicles's picture

Tone deafness is defined as the inability to discriminate between musical notes also known as amusia, tune deafness, dysmelodia, and dysmusia. Famous leaders including President Theodore Roosevelt and Ernesto "Che" Guevara have suffered from this often embarrassing hearing impairment. In an epic fail, Che once tried to woo some chicas at a dance by performing a tango while the band was playing a lively Brazilian (sigh). These are the kinds of people you would never bring to a karaoke bar...unless, of course you were tone deaf too. In that case it wouldn't really matter now would it?

Stress signals link pre-existing sickness with susceptibility to bacterial infection

Mitochondrial diseases disrupt the power generating machinery within cells and increase a person's susceptibility to bacterial infection, particularly in the lungs or respiratory tract.

How young mice phone home: Study gives clue to how mothers' brains screen for baby calls

Emory University researchers have identified a surprising mechanism in the brains of mother mice that focuses their awareness on the calls of baby mice. Their study, published June 11 in Neuron, found that the high-frequency sounds of mice pups stand out in a mother's auditory cortex by inhibiting the activity of neurons more attuned to lower frequency sounds.

Biomedical training, research at IU receives $3 million federal grant

In 1979 Chancellor's Professor David Pisoni brought the first two postdoctoral researchers to Indiana University Bloomington when he was awarded a five-year training grant by the National Institute of Neurological and Communicative Disorders. Today, the same grant supports six postdoctoral researchers, six doctoral students and six medical students in Bloomington and Indianapolis.

Scripps research scientists discover molecular defect involved in hearing loss

La Jolla, CA, May 11, 2009 -Scientists from The Scripps Research Institute have elucidated the action of a protein, harmonin, which is involved in the mechanics of hearing. This finding sheds new light on the workings of mechanotransduction, the process by which cells convert mechanical stimuli into electrical activity.

Risk of autism tied to genes that influence brain cell connections

In three studies, including the most comprehensive study of autism genetics to date, investigators funded in part by the National Institutes of Health have identified common and rare genetic factors that affect the risk of autism spectrum disorders. The results point to the importance of genes that are involved in forming and maintaining the connections between brain cells.

Stanford researcher's discovery of ion channel turns ear on its head

STANFORD, Calif. -- Scientists thought they had a good model to explain how the inner ear translates vibrations in the air into sounds heard by the brain. Now, based on new research from the Stanford University School of Medicine, it looks like parts of the model are wrong.

New insights into progressive hearing loss

In parallel studies in human and mouse, two groups of researchers have come to the same conclusion: that a new kind of gene is associated with progressive hearing loss. The new gene - called a microRNA - is a tiny fragment of RNA that affects the production of hundreds of other molecules within sensory hair cells of the inner ear.

New stem cell therapy may lead to treatment for deafness

Sheffield, England - March 23, 2009 - Deafness affects more than 250 million people worldwide. It typically involves the loss of sensory receptors, called hair cells, for their "tufts" of hair-like protrusions, and their associated neurons.

Nanotech coating could lead to better brain implants to treat diseases

Biomedical and materials engineers at the University of Michigan have developed a nanotech coating for brain implants that helps the devices operate longer and could improve treatment for deafness, paralysis, blindness, epilepsy and Parkinson's disease.

Vitamin supplements may protect against noise-induced hearing loss

Vitamin supplements can prevent hearing loss in laboratory animals, according to two new studies, bringing investigators one step closer to the development of a pill that could stave off noise-induced and perhaps even age-related hearing loss in humans.



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