cysts
The molecular functions of Folliculin (FLCN) are poorly understood, but indirect interactions between FLCN and AMPK (of the mTOR signaling network) mediated by FNIP1 and FNIP2 have been firmly established (Baba M et al, 2006; Hasumi H et al, 2008; Takagi Y et al, 2008), suggesting a role for FLCN in nutrient/energy-sensing through the AMPK/mTORC1 signaling pathway.
A recent publication in PNAS (Hasumi Y. et al 2009.
BATON ROUGE -- For Sophie Warny, LSU assistant professor of geology and geophysics and curator at the LSU Museum of Natural Science, years of patience in analyzing Antarctic samples with low fossil recovery finally led to a scientific breakthrough.
Polycystic ovary syndrome, a common condition among women, can be relieved by the use of acupuncture and exercise. This has been shown by a recent study at the Sahlgrenska Academy, University of Gothenburg, Sweden.
SAN FRANCISCO, CA---This month's Ophthalmology, the journal of the American Academy of Ophthalmology, reports on use of bevacizumab (Avastin), to benefit diabetic patients with macular edema as well as people who develop cystoid macular edema after cataract surgery. Bevacizumab is also used to treat some cancers.
Acute kidney injury (AKI) is a frequent complication in patients in intensive care. A new laboratory test called urine neutrophil gelatinase associated lipocalin (NGAL) helps predict if patients will develop acute kidney injury, reports an upcoming study in the Journal of the American Society of Nephrology (JASN).
NEW YORK -- New data collected at Columbia University Medical Center and by the Mount Sinai School of Medicine are helping researchers understand the extent to which a certain protein -- NGAL -- can play a significant role in marking chronic kidney disease resulting from HIV while at the same time distinguishing nephropathy from more common causes such as diabetes and hypertension.
"Single-Shot" Vaccines May Protect Against H5N1 Influenza Virus
WASHINGTON, DC -- Research published today in Science Express from the journal Science demonstrates the first definitive link between mutations in the gene DICER1 and cancer.
Blacksburg, Va. -- A collaboration of researchers, which includes scientists at the Virginia Bioinformatics Institute (VBI) and Virginia Tech, have completed the genome sequence of Azotobacter vinelandii, uncovering important genetic information that will contribute to a more complete understanding of the biology of this versatile, soil-living bacterium.
St. Louis, April 20, 2009 -- The search for the cause of an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about how the cancer develops and potentially sheds light on the development of other cancers.
A handful of proteins, detected in incredibly tiny amounts, may one day help doctors distinguish between a harmless lesion in the pancreas and a potentially deadly one, say researchers at Fox Chase Cancer Center.
Research reveals that a unique combination of genes inherited less than 10,000 years ago allows the parasite responsible for toxoplasmosis to infect virtually all warm-blooded animals. Parasite life cycles are complex and thought to develop over long periods with their hosts. This study reveals that parasites sometimes adapt rapidly to new hosts, indicating that host-parasite relationships may not always represent stable, long-term associations.
Research at Washington University School of Medicine in St. Louis reveals that a unique combination of genes inherited less than 10,000 years ago allows the parasite responsible for toxoplasmosis to infect virtually all warm-blooded animals. Parasite life cycles are complex and thought to develop over long periods with their hosts. This study reveals that parasites sometimes adapt rapidly to new hosts, indicating that host-parasite relationships may not always represent stable, long-term associations.
An anti-epileptic drug may help treat symptoms of a condition that affects as many as 1 in 10 people in developing countries. In a clinical study the drug helped reduce the incidence of seizures in people whose central nervous systems have become infected with the pork tapeworm taenia solium. The condition is associated with seizures, headache, and other neurological symptoms, but of these, seizures are the most common, occurring in nearly 90 percent of all patients.
