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Discovery of genetic toggle switch inches closer to possible diabetes cure

CINCINNATI - Scientists have identified a master regulator gene for early embryonic development of the pancreas and other organs, putting researchers closer to coaxing stem cells into pancreatic cells as a possible cure for type1 diabetes.

Researchers at Cincinnati Children's Hospital Medical Center report their findings in the July 21 Developmental Cell.

Alpha-fetoprotein can affect the development of rat colons?

Mammalian alpha-fetoprotein (AFP) is a single-chain glycoprotein and altered serum AFP levels have been observed concurrent with aberrant growth manifestations in some congenital defects and cancer. The gut development during late gestation and early neonatal period is accompanied by changes in the synthesis of AFP, and abundance declines significantly during gut development.

Study examines effect of heart surgery on employment

Hannover, Germany - March 30, 2009 - A new studying appearing in Congenital Heart Disease compares the careers and long-term occupational successes of men and women who underwent surgery for congenital heart disease to those of the general population.

Scientists discover why teeth form in a single row

A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published today in the journal Science. When completely understood, the genetic program described in the study may help guide efforts to re-grow missing teeth and prevent cleft palate, one of the most common birth defects.



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